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Refining method of traditional Chinese medicine composition water extract containing ginseng

A refining method and composition technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, and can solve problems such as drug efficacy reduction, heat damage, and loss of active ingredients

Active Publication Date: 2010-07-21
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The refining of traditional Chinese medicine is mostly based on the polarity difference between components (solvent precipitation or extraction, adsorption separation, etc.) Component loss or heat damage, resulting in reduced efficacy, etc.

Method used

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  • Refining method of traditional Chinese medicine composition water extract containing ginseng
  • Refining method of traditional Chinese medicine composition water extract containing ginseng
  • Refining method of traditional Chinese medicine composition water extract containing ginseng

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The raw material drug formula is:

[0045] Ginseng 102g, Polygonatum 136g, Atractylodes 68g, Sophora flavescens 56g, Poria cocos 83g, Ophiopogon japonicus 136g, Polygonum multiflorum 83g, Rehmannia glutinosa 102g, Cornus officinalis 136g, Coptis 56g, Peilan 56g, Lychee seed 136g, Epimedium 56g, Anemarrhena 68g, Salvia miltiorrhiza 89g, Pueraria 136g, Digupi 83g.

[0046] The refining method is:

[0047] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0048]b. Add 6 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 5 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use;

[0049] c. Polygonatum, Sophora flavescens, Rehmannia, Polygonum multiflorum, Poria cocos, Coptis chinensis, Salvia miltiorrhiza, Lychee core, Digupi, add 9 times the amount of water, decoct twice for 2 hours each time, filter the extract, an...

Embodiment 2

[0055] The raw material drug formula is:

[0056] Ginseng 42g, Polygonatum 200g, Atractylodes 30g, Sophora flavescens 60g, Poria cocos 35g, Ophiopogon japonicus 200g, Polygonum multiflorum 35g, Rehmannia glutinosa 120g, Cornus officinalis 50g, Coptis 60g, Peilan 30g, Lychee seed 150g, Epimedium 30g, Anemarrhena 100g, Salvia miltiorrhiza 35g, Pueraria 200g, Digupi 30g.

[0057] The refining method is:

[0058] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0059] b. Add 9 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 3 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use;

[0060] c. Polygonatum, Sophora flavescens, Rehmannia, Polygonum multiflorum, Poria cocos, Coptis chinensis, Salvia miltiorrhiza, Lychee core, Digupi, add 7 times the amount of water, decoct 2 times, 1 hour each time, filter the extract, and ...

Embodiment 3

[0066] The raw material drug formula is:

[0067] Ginseng 160g, Polygonatum 50g, Atractylodes 100g, Sophora flavescens 20g, Poria cocos 100g, Ophiopogon japonicus 50g, Polygonum multiflorum 100g, Rehmannia glutinosa 50g, Cornus officinalis 200g, Coptidis 20g, Perrin 60g, Lychee seed 75g, Epimedium 60g, Anemarrhena 30g, Salvia miltiorrhiza 120g, Pueraria 50g, Digupi 100g.

[0068] The refining method is:

[0069] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0070] b. Add 5 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 6 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use;

[0071] c. Polygonatum, Sophora flavescens, Rehmannia, Polygonum multiflorum, Poria cocos, Coptis chinensis, Salvia miltiorrhiza, Lychee core, Digupi, add 11 times the amount of water, decoct once, decoct for 3 hours, filter the extract, a...

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Abstract

The invention discloses a refining method of a traditional Chinese medicine composition water extract. The traditional Chinese medicine composition comprises ginseng, rhizoma polygonati, rhizoma atractylodis, radix sophorae flavescentis, Tuckahoe, ophiopogon root, prepared Polygonum multiflorum, rehmanniae, dogwood, rhizoma coptidis, eupatorium and the like, and can treat diabetes mellitus. The method carries out refining on the traditional Chinese medicine composition by filtering through an inorganic ceramic membrane; the method has high transfer rate of the effective components which can be industrially produced; the feed liquid has simple process; and the inorganic ceramic membrane is convenient to clean and can be repeatedly regenerated. The invention relates to a refining method of the traditional Chinese medicine composition water extract containing the ginseng.

Description

technical field [0001] The invention relates to a method for refining the water extract of a Chinese medicine composition, in particular to a method for refining the water extract of a Chinese medicine composition through inorganic ceramic membrane filtration. Background technique [0002] The main purpose of the production process of traditional Chinese medicine preparations is to enrich the active ingredients and remove invalid impurities. The refining of traditional Chinese medicine is mostly based on the polarity difference between components (solvent precipitation or extraction, adsorption separation, etc.) Component loss or heat damage, resulting in reduced efficacy, etc. Inorganic ceramic membrane separation technology is based on the principle of sieving, which can separate suspended particles of 0.05-10 μm and some macromolecular impurities in the solution. Inorganic ceramic membranes for traditional Chinese medicine separation are mostly Al 2 o 3 The ceramic me...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10
Inventor 陈占立孙长荣魏学君石润波范文成
Owner HEBEI YILING MEDICINE INST
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