Peach blossom or peach leaf general flavone and application thereof in preparing medicines or health care products for lowering blood sugar and fat and preventing and/or treating diabetes and complications

A technology of total flavonoids and hypoglycemia, which is applied in the field of prevention and/or treatment of diabetes and its complications drugs or health products, and preparation of hypoglycemic and blood lipids. It can solve the problems of lowering blood sugar, drug damage, and complex components of traditional Chinese medicines to achieve safety. Good, low-cost results

Active Publication Date: 2010-09-01
王宝民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs can effectively lower blood sugar, their use is strictly limited due to the damage of the drug to the body due to long-term use
At present, there are also traditional Chinese medicine preparations for the treatment of diabetes. They have been proved to have a certain effect on the regulation of diabetes. However, the composition of traditional Chinese medicine is complex, the efficacy of each component is not clear, and the quality is not easy to control, which is not conducive to the preparation of pharmaceutical preparations.
In addition, the effects of existing diabetes drugs are limited to lowering blood sugar, and cannot reduce and delay the development of chronic diabetic lesions.

Method used

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  • Peach blossom or peach leaf general flavone and application thereof in preparing medicines or health care products for lowering blood sugar and fat and preventing and/or treating diabetes and complications
  • Peach blossom or peach leaf general flavone and application thereof in preparing medicines or health care products for lowering blood sugar and fat and preventing and/or treating diabetes and complications
  • Peach blossom or peach leaf general flavone and application thereof in preparing medicines or health care products for lowering blood sugar and fat and preventing and/or treating diabetes and complications

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] According to the peach blossom initial extract of the present embodiment, prepare through the following steps:

[0034] (1), get 1kg of dried peach blossoms of longevity peaches, put them into water for half an hour by weight ratio of 1:10 (flowers: water), reflux for 1 hour at a constant temperature in a water bath at 75°C, filter, and reflux the filter residue for the second time. Extract 3 times and combine the extracts.

[0035](2), add chitin to the extract obtained in step (1), flocculate and precipitate, remove the precipitate to obtain a clarified extract, concentrate the extract under reduced pressure at 75°C, and dry it in vacuum at 80°C for 24 hours to obtain dry primary extract It is about 131.5 grams. The qualitative test shows that the primary extract contains flavonoids, organic acids, phenols, glycosides, polysaccharides, triterpenes and other chemical components.

Embodiment 2

[0037] According to the peach blossom primary extract of the present embodiment, the dried peach blossoms of juicy peaches are used as raw material, extracted according to the same method as in Example 1, and finally obtain about 118.8 g of the primary extract, and the qualitative test result is the same as that of Example 1.

Embodiment 3

[0039] According to the peach blossom initial extract of the present embodiment, take flat peach dried peach blossom as raw material, extract according to the method identical with embodiment 1, finally obtain about initial extract 125.4g, qualitative test result is with embodiment 1.

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Abstract

The invention relates to peach blossom or peach leaf general flavone, a peach blossom or peach leaf original extract, a pharmaceutical composition containing a peach blossom or peach leaf original extract and / or peach blossom or peach leaf general flavone, and application thereof in preparing medicines or health care products for lowering blood sugar and fat and preventing and / or treating diabetes and complications thereof. In the invention, the peach blossom or peach leaf original extract is obtained by taking a rosaceous plant-peach blossom or peach leaves as raw materials and then extracting with water or alcohol with the carbon number of 1-6; and the peach blossom or peach leaf general flavone is obtained by utilizing macroporous resin to carrying out absorbing, separating and purifying on the original extract. The peach blossom or peach leaf original extract, the peach blossom or peach leaf general flavone and the pharmaceutical composition containing the peach blossom or peach leaf original extract and / or the peach blossom or peach leaf general flavone have good curative effect, few side effects and low cost in preventing and treating diabetes, especially Type II diabetes and complications thereof.

Description

technical field [0001] The present invention relates to peach flower or peach leaf total flavonoids, peach flower or peach leaf primary extract, and their use in preparing medicines or health care products for lowering blood sugar and blood fat, preventing and / or treating diabetes and its complications. Background technique [0002] Diabetes (diabetes) is caused by genetic factors, immune dysfunction, microbial infection and its toxins, free radical toxins, mental factors and other pathogenic factors acting on the body to cause hypofunction of islets and insulin resistance. , water and electrolytes and a series of metabolic disorder syndromes, clinically characterized by hyperglycemia. [0003] Diabetes is mainly divided into type 1 diabetes and type 2 diabetes. Among diabetic patients, type 2 diabetes accounts for about 95%, and type 2 diabetes is becoming more and more frequent and younger. As the blood sugar continues to rise, it causes systemic metabolic disorders, whi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P3/10A61P3/06A23L1/29A61K127/00A61K133/00A23L33/00
Inventor 王宝民
Owner 王宝民
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