Cefdinir compound and new preparation method thereof

A technology of cefdinir and its compounds, which is applied in the field of cefdinir compounds and its new preparation method, and can solve the problems of large differences in pentafluorophenol structure, complicated operation, and low product purity
CN101817835AInactive Publication Date: 2010-09-01HAINAN MEIDA PHARMA
7 Cites 11 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
HAINAN MEIDA PHARMA
Publication Date
2010-09-01
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a cefdinir compound and a new preparation method thereof. The method prepares the cefdinir by performing reaction on (Z)-2-(2-aminothiazole-4-group)-2-triphenylmethyl iminoacetic acid serving as an initial raw material, pentafluorophenol serving as an activating group and 7-AVCA.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a cefdinir compound and a new preparation method thereof, belonging to the technical field of medicine. Background technique

[0002] Cefdinir, its chemical name is: (6R,7R)-7-[(2-amino-4-thiazolyl)-(oximino)acetoxy]amino]-3-vinyl-8-oxo-5 -Thia-1-azabicyclo[4.2.0]oct-2-ene-2-hydroxy acid, molecular formula: C 14 h 13 N 5 0 5 S 2 , molecular weight: 395.42, structural formula:

[0003]

[0004] Cefdinir is a broad-spectrum antibiotic that inhibits the synthesis of bacterial cell walls and has a broad antibacterial spectrum against most Gram-positive and Gram-negative bacteria, especially Staphylococcus and Streptococcus among Gram-positive bacteria. , has stronger antibacterial activity than previous oral cephalosporins, and its mode of action is bactericidal. It is stable against β-lactamase produced by various bacteria and has excellent antibacterial activity against β-lactamase-producing bacteria.

[0005] Chinese ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More