16 results about "Acid activation" patented technology

The invention relates to the technical field of drug-loaded microparticles, in particular to a preparation method and application of medical stone / PLGA composite drug-loaded microparticles, medical stone and PLGA are prepared into a structure with activated nano medical stone as a core and a PLGA polymer as a shell through the processes of ball milling, acid activation, emulsification, solvent volatilization and the like, and the medical stone and the PLGA are synergistically matched, so that the drug-loaded microparticles have the advantages that the drug-loaded microparticles are uniform in particle size distribution, and the drug-loaded microparticles have good drug-loaded performance. Firstly, the hydrogel has intelligent responsiveness, can accelerate degradation in alkaline and enzyme environments of wound surfaces, and realizes accurate release of drugs as required; secondly, the long-acting controlled release property is shown, and a dual sustained release barrier is constructed through medical stone adsorption and PLGA wrapping, so that the medicine is released for more than 72 hours at a constant speed following zero-order dynamics, and burst release is effectively avoided. And thirdly, when the drug-loaded particles are used for hydrogel, the drug-loaded particles in nanoscale are combined with the hydration effect of a hydrogel matrix, so that the efficient permeability of the drug in the cuticle is greatly improved.

The invention relates to the technical field of gas adsorption materials, in particular to special silica gel for pressure swing adsorption hydrogen extraction and a preparation method thereof. The special silica gel for pressure swing adsorption hydrogen extraction comprises pretreated adsorption silica gel and advanced treatment adsorption silica gel, wherein the pretreated silica gel is specially used for capturing polar molecules; and the silica gel is deeply treated to accurately adsorb small-molecule gas. During preparation, a graded functionalization strategy is adopted, the stability of a silica gel framework is enhanced through acid activation, a multi-stage adsorption interface is constructed through amino / fluorocarbon directional grafting, and active components are fixed through chemical bonding to avoid loss. During application, a double-tower pressure swing adsorption process is adopted, the pretreatment adsorption tower preferentially removes strong adsorbate, the deep treatment adsorption tower improves hydrogen purity through hydrophobic screening, and gradient pressure reduction and pulse nitrogen desorption technologies are matched, so that efficient regeneration of the adsorbent is realized. A single material system breaks through a mass transfer barrier of a traditional multi-adsorbent combination, has the characteristics of high-selectivity adsorption and low-energy-consumption desorption, and is suitable for efficient recovery of hydrogen resources in synthesis ammonia tail gas.

The invention provides low-GI coarse cereal and mixed bean brewing powder and a preparation method and application thereof.The preparation method comprises the steps that firstly, tartary buckwheat bran is treated with atmospheric pressure cold plasma, composite cellulose enzymolysis and calcium ion induction gelation are combined, a porous shear thinning gel structure is formed through directional freezing and thawing, and the problem of caking during brewing is solved; secondly, a two-stage fermentation process is adopted, monascus and lactobacillus casei are inoculated in the initial stage, a monascus secretase system is used for breaking cell walls to release sugar, a hypha network is constructed, and embedding of rosa roxburghii tratt pomace polyphenol and synthesis of monacolin K and GABA are synchronously achieved; in the later period, propionibacterium freudenreichii is inoculated to convert lactic acid to generate propionic acid, insulin sensitivity is improved through GABA, and the propionic acid activates GLP-1 to delay gastric emptying, so that the GI value of the product is remarkably reduced. The finally prepared product is fast to brew and disperse and smooth in taste, has the effects of lowering cholesterol and regulating blood sugar, and provides novel healthy food for people with diabetes and metabolic syndromes.

This application provides an LCP thin film assembly, its preparation method, and its application. The preparation method includes: surface modification of the LCP thin film to obtain an activated surface rich in carboxyl and hydroxyl groups, followed by hot pressing of the LCP thin film with the activated surface; the LCP thin film assembly includes a multilayer LCP thin film bonded by hot pressing, wherein no adhesive is contained between any two adjacent LCP thin films, and the interface region between any two adjacent LCP thin films forms a homogenized molecular-level bonding layer through melt recrystallization; the preparation method of this application introduces active functional groups through surface modification methods such as alkaline hydrolysis and acid activation, achieving interlayer chemical bonding during hot pressing, significantly improving interlayer bonding strength, avoiding the risks of bubbling and delamination, and retaining the inherent excellent high-frequency performance and dielectric properties of the LCP thin film; this preparation method, when applied to the preparation of LCP thin film probe cards, can produce thin film probe cards with excellent interlayer bonding strength and high-frequency performance.

The application discloses sludge-based magnetic biochar based on multiple wastes and a preparation method and application thereof, and relates to the technical field of environmental functional materials, and comprises the following steps: dehydrating, drying, crushing and screening residual sludge by using polyaluminum ferric chloride; freeze-drying, crushing and screening biogas residues; crushing and screening industrial iron-containing waste; the industrial iron-containing waste is a mixture of red mud and pickling waste liquid; municipal residual sludge, kitchen biogas residues and red mud-pickling waste liquid are used as raw materials; magnetic biochar is prepared by means of synergistic pore forming, staged pyrolysis, acid activation and sulfonic acid group grafting double modification; a multi-level pore structure is formed and magnetic particles and polar functional groups are loaded; the finally prepared magnetic biochar can efficiently adsorb and remove GenX, F-53B and ADONA, and has the advantages of fast magnetic separation and stable circulation.

The invention belongs to the technical field of underground water remediation, and particularly relates to a passivated zero-valent iron activation method, an underground water remediation system, a remediation method and application. The activation method of the passivated zero-valent iron, provided by the invention, comprises the following steps: mixing and reacting a small molecule acid activation solution and the passivated zero-valent iron under the condition that the pH value is 5.0-7.0 to obtain activated zero-valent iron; micromolecular acid in the micromolecular acid activating solution is selected from citric acid and / or oxalic acid. According to the method, the passivated zero-valent iron in the underground water in-situ reaction zone is activated by using specific green natural small-molecule organic acids (citric acid and oxalic acid) in a specific pH environment, so that the stability and the long-term effect of a system for repairing the underground water by using the zero-valent iron are improved, and a low-cost in-situ activated passivated zero-valent iron in-situ reaction zone technology is constructed; the reduction degradation efficiency of pollutants can be improved, and the underground water composite pollutants can be efficiently removed in a long-acting manner.

The application discloses an acid-activated anti-infection nanovesicle and a preparation method and application thereof, which is prepared by loading an acid-activated photosensitizer BODIPY molecule with antibacterial function into human skin fibroblast-derived nanovesicles, and is named as BODIPY@FNVs; the BODIPY molecule in the BODIPY@FNVs can be activated in an acidic environment.The advantages of the application include that the BODIPY is combined with human skin fibroblast-derived nanovesicles (FNVs), the preparation method is simple and low in cost, the antibacterial deficiency of the FNVs is compensated, and the tissue repair and infection control effects are enhanced; in an acidic environment caused by bacterial infection, the BODIPY@FNVs generates singlet oxygen under light irradiation, and releases biological active ingredients such as mRNA and proteins in the vesicle interior, and jointly plays the roles of sterilization, bacteriostasis and promotion of tissue repair, accelerates wound healing, has good biological safety, has wide application prospects and popularization value in the treatment of various infectious diseases, and has wide applicability.

This invention discloses a polyaluminum chloride-based composite flocculant and its preparation method, belonging to the field of water treatment agent technology. The preparation method includes: acid activation of natural attapulgite to obtain acid-modified nano-attapulgite crystal nuclei; hydrolysis of liquid polyaluminum chloride, basic zirconium chloride, and ferric chloride to form clusters, followed by the addition of polyepoxysuccinic acid of a specific molecular weight for dynamic shielding to obtain a shielding liquid; dispersing the crystal nuclei into the shielding liquid; and slowly adding carboxymethyl chitosan solution and anionic polyacrylamide solution sequentially at a specific rotation speed to obtain the liquid composite flocculant. This invention overcomes the problem of easy gelation of high-concentration liquid flocculants by strictly controlling the dosing sequence and the dynamic spatial shielding of polyepoxysuccinic acid; by utilizing the synergistic effect of zirconium-aluminum bimetallic flocculant and the specific chelation of carboxymethyl chitosan, excellent low-temperature and low-turbidity water removal rate is achieved while strictly controlling residual aluminum; combined with acid-modified heavy crystal nuclei, the sedimentation rate of flocs is significantly improved.

The application discloses an enhanced anti-coagulation and anti-bacterial hemodialysis hollow fiber membrane and a preparation method thereof, and belongs to the technical field of medical membrane materials. The acid activation-polydopamine coating-sulfonated grafting modification of halloysite nanotubes is carried out in the application, so that the surface sulfonic acid group density of the halloysite nanotubes reaches 0.8-2.1 mmol / g, and the Zeta potential is less than or equal to-30 mV. The modified halloysite is dispersed in a polar aprotic solvent in advance, is incorporated into a polymer matrix after ultrasonic treatment, is filtered through a sintering filter element with a diameter of less than or equal to 5 mu m, is defoamed, is spun by using a dry spraying-wet spinning method, and is prepared into a finished product through coagulation, rinsing and drying. The application constructs a heparin-like negative charge layer, so that the activated partial thromboplastin time (APTT) is greater than or equal to 55 s, platelet adhesion and protein adsorption are significantly inhibited, and the application has a broad-spectrum antibacterial performance. The rigid halloysite induces the formation of through channels, so that the pain point that a high-flux membrane is easy to damage red blood cells is solved, the process is stable, and the application is suitable for industrial production.

The invention belongs to the technical field of water environment heavy metal pollution remediation, and provides a magnetic porous loess organic composite material and a preparation method and application thereof. The preparation method of the magnetic porous loess organic composite material comprises the following steps: carrying out acid activation treatment on a loess material to obtain an acid-activated loess material; mixing the acid activated loess material with an alkaline pore-forming agent in water to form homogeneous slurry, dropwise adding an acid solution to form mixed slurry, and reacting under a stirring condition to obtain a porous loess material; the method comprises the following steps: assembling a porous loess material and Fe3O4 nanoparticles in the presence of sodium carboxymethyl cellulose to obtain a Fe3O4 / loess magnetic composite material; and mixing the Fe3O4 / loess magnetic composite material, an amino compound and an aldehyde compound, and carrying out Schiff base reaction on the amino compound and the aldehyde compound to obtain the magnetic porous loess organic composite material. The method solves the problems that the adsorption effect of natural loess on heavy metal ions is limited, and the problem exists in the compounding process of the natural loess and Fe3O4 nanoparticles.

The invention discloses the synthetic method for preparing 3,4-dichlorocoumarins by 4-chlorocoumarins, using 4-chlorocoumarin derivatives as raw materials, using hydrochloric acid as chlorine source, in the presence of visible light catalyst and external oxidant, selective chlorination reaction occurs in an organic solvent by visible light irradiation, and 3,4-dichlorocoumarin derivatives are obtained. Application of the present invention 3,4-dichlorocoumarin derivatives can be prepared under mild conditions using simple and easy-to-get 4-chlorocoumarins under visible light drive, the yield of product can reach up to 98%, and the fastest reaction can be completed in 10 minutes, also with the characteristic of safety and environmental protection and high regioselectivity and substrate adaptability. In short, the present invention overcomes the reaction efficiency of Lewis acid activation method is not enough, the defect of large excess reagent use and the dependence on substrate substituents, also solves the deficiencies such as not safe, low efficiency when 4-chlorocoumarins are further chlorinated under visible light catalysis in the prior art.

This invention discloses a red mud-based asphalt modifier, its preparation method, and its application, relating to the field of solid waste modified asphalt technology. The preparation method of the red mud-based asphalt modifier mainly includes three core steps: acid activation and structural reconstruction, phytic acid surface chelation functionalization, and octadecylamine hydrophobic grafting. This invention can simultaneously optimize the pore structure of red mud, activate surface chemical activity, and reverse surface wettability. The red mud-based asphalt modifier of this invention not only has excellent asphalt compatibility but also adsorbs light components in asphalt through its porous structure and forms physical entanglement between long-chain organic molecules on its surface and asphalt components, thereby improving the mechanical properties of asphalt.

The invention discloses a method for synthesizing sulfonyl cyclobutyl ketone by using phosphine to catalyze bicyclo [1.1. 0] butane, which specifically comprises the following steps: in a nitrogen atmosphere, mixing the bicyclo [1.1. 0] butane containing carbonyl or sulfuryl with sulfonyl hydrazone, reacting in the presence of alkali and a phosphine catalyst, and post-treating and purifying the reaction liquid to obtain the target product sulfonyl cyclobutyl ketone. According to the method, a common transition metal or Lewis acid activation strategy is abandoned, the phosphine catalyst is adopted for efficiently activating the bicyclo [1.1. 0] butane for the first time, and a new way is opened up for functionalization of the bicyclo [1.1. 0] butane. The application range of substrates is wide, and monosubstituted and polysubstituted compounds modified by electron-withdrawing and electron-donating groups are covered. The method for synthesizing sulfonyl cyclobutyl ketone through phosphine catalysis is reported for the first time, and under the optimized condition, the highest product separation yield can reach 87%.

The invention discloses an iron-loaded multi-stage modified biochar material and a preparation method and application thereof, and relates to the technical field of environmental remediation materials.The preparation method of the iron-loaded multi-stage modified biochar material comprises the following steps that S1, a biochar raw material and an acid activator are mixed and subjected to an acid activation reaction, and an acid activated biochar raw material is obtained; s2, in an inert atmosphere, carrying out heat treatment on the acid-activated biochar raw material to obtain modified biochar; s3, mixing the modified biochar with an iron source solution, dropwise adding a KOH solution under a stirring condition, adjusting the pH value to 10 + / -0.2, standing, washing with water to be neutral, and drying to obtain an iron-loaded multi-stage modified biochar material; the iron source solution comprises ferrous ions and iron ions. According to the invention, an acid activator and an iron source are used as modifiers, and a novel iron-loaded biochar material for efficiently passivating heavy metals in polluted soil is obtained through a step-by-step modification method.

The invention discloses an EGDMA polyester adsorbent, a preparation method thereof and application of the EGDMA polyester adsorbent in synergistic adsorption of NH3 and CO2 in marsh gas, and the preparation method of the EGDMA polyester adsorbent comprises the following steps: firstly, dissolving EGDMA in an organic solvent, adding an initiator under an oxygen isolation condition for polymerization, then removing the organic solvent, then drying, then performing acid activation, then separating, and then drying to obtain the EGDMA polyester adsorbent. The EGDMA polyester adsorbent firstly adsorbs NH3, an NH3 ring-opening reaction is utilized, amino-NH2 and hydroxyl-OH are efficiently introduced to a polyester skeleton, efficient adsorption sites are constructed, and then CO2 is adsorbed. The EGDMA polyester adsorbent can efficiently separate NH3 and CO2 in sludge anaerobic digestion biogas at the same time, has high selectivity to NH3 and CO2, and can realize collaborative adsorption and separation of NH3 and CO2, thereby purifying biogas and promoting resource recovery.

The application discloses a three-dimensional high-thermal-conductivity attapulgite / graphene oxide aerogel composite phase change material and a preparation method thereof. The preparation method comprises the following steps: (1) treating attapulgite by acid activation; (2) mixing and stirring attapulgite nanofibers, a silane coupling agent and ethanol to obtain aminoized attapulgite nanofibers; (3) mixing graphene oxide nanosheets, microfibrillated cellulose and deionized water to form a uniform graphene oxide suspension; (4) adding the aminoized attapulgite nanofibers into the graphene oxide suspension and mixing and stirring to obtain a uniform dispersion liquid, and the dispersion liquid is subjected to a hydrothermal reaction to prepare attapulgite / graphene oxide hydrogel with a three-dimensional structure; (5) freezing to obtain attapulgite / graphene oxide aerogel; and (6) vacuum impregnating the attapulgite / graphene oxide aerogel with a phase change material to obtain the composite phase change material. The composite phase change material can realize extremely high energy storage density, excellent leakage prevention performance and good thermal conductivity.