Application of traditional Chinese medicine composition for preparing nitric oxide generating medicine

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, active ingredients of hydroxyl compounds, plant/algae/fungus/moss components, etc., can solve problems such as the application of undisclosed traditional Chinese medicine compositions, and achieve the reduction of myocardial ischemia-reperfusion injury, The effect of promoting NO production

Active Publication Date: 2010-09-15
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two patents do not disclose the application of the traditional Chinese medicine composition in the preparation of drugs for promoting the production of nitric oxide

Method used

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  • Application of traditional Chinese medicine composition for preparing nitric oxide generating medicine
  • Application of traditional Chinese medicine composition for preparing nitric oxide generating medicine
  • Application of traditional Chinese medicine composition for preparing nitric oxide generating medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] a) The raw material drug formula is:

[0053] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0054] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 19.8g

[0055] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g;

[0056] b) Crushing process of medicinal materials:

[0057] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0058] c) Extraction concentration and dr...

Embodiment 2

[0064] a) The raw material drug formula is:

[0065] Ginseng 66g Leech 52.8g Wood Beetle 46.2g Frankincense (made) 13.2g

[0066] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 59.4g

[0067] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0068] b) Crushing process of medicinal materials:

[0069] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 70-90 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0070] c) Extraction concentration and dryin...

Embodiment 3

[0075] Embodiment 3: the preparation of pill

[0076] a) The raw material drug formula is:

[0077] Ginseng 39.6g Leech 66g Wood Beetle 46.2g Frankincense (made) 13.2g

[0078] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 46.2g

[0079] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0080] b) Crushing process of medicinal materials:

[0081] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powder after powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the powder is 10-20 μm;

[0082] c) Extraction concentration and drying process:

[0083] Add water to extract the volatile oil of Jiangxiang and s...

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Abstract

The invention discloses application of a traditional Chinese medicine composition for preparing a nitric oxide generating medicine. The traditional Chinese medicine composition consists of ginseng, leech, centipede, scorpio, ground beeltle, cicada slough, root of common peony, borneol and the like and has the effects of supplementing qi, activating blood circulation as well as nourishing and promoting blood circulation. The traditional Chinese medicine composition is proved by experiment that concentration of nitric oxide in blood plasma can be increased to ease ischemia-reperfusion injury.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the present invention relates to an application of a traditional Chinese medicine composition in the preparation of a drug for promoting nitric oxide generation, which belongs to the field of traditional Chinese medicine application. Background technique [0002] Acute myocardial infarction (AMI) is a dangerous disease with a high mortality rate and great harm. Therefore, coronary artery recanalization therapy (thrombolysis or emergency coronary intervention) has become the most important goal and evaluation index to recanalize the blocked coronary artery as soon as possible and restore effective myocardial reperfusion. However, after AMI coronary artery recanalization, there are still the following problems to fully benefit the myocardium: 1. No reflow or slow blood flow phenomenon, that is, although the coronary artery has been opened (without mech...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61P9/10A61K35/64A61K35/62A61K31/045A61K35/646A61K35/648
Inventor 杨跃进程宇彤
Owner HEBEI YILING MEDICINE INST
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