Traditional Chinese medicine capable of treating complicated symptom of diabetes and stagnant heat and application thereof

A technology for diabetes and blood stasis, applied in the field of traditional Chinese medicine compound, can solve the problems of lack of clinical drug efficacy research, inconsistent treatment, single prescription, proven prescription, etc., and achieve the effect of no toxic side effects, good protective effect, and reliable curative effect

Active Publication Date: 2010-09-29
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many drugs for the treatment of diabetes and its complications. Although the western medicines used clinically have certain curative effects, most of them have relatively large adverse reactions, such as rebound after drug withdrawal, liver and kidney damage, rhabdomyolysis and other side effects. , cure the symptoms but not the root cause, and traditional Chinese medicine has its unique advantages in the treatment of diabetes, which has the advantages of long-lasting curative effect and no obvious side effects. , and the prescriptions of traditional Chinese medicine are based on different basis, and the treatment principles are not unified. At present, there is no report on the medicine for diabetes combined with blood stasis and heat. It is of great significance to explore efficient and non-toxic drugs for the treatment of diabetes and its complications of blood stasis and heat

Method used

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  • Traditional Chinese medicine capable of treating complicated symptom of diabetes and stagnant heat and application thereof
  • Traditional Chinese medicine capable of treating complicated symptom of diabetes and stagnant heat and application thereof
  • Traditional Chinese medicine capable of treating complicated symptom of diabetes and stagnant heat and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. The composition of raw materials of Chinese medicine compound:

[0031] 15 grams of raw land, 15 grams of salvia, 10 grams of paeonol, 6 grams of coptis, 10 grams of red peony, 15 grams of ghost arrow feathers.

[0032] 2. The preparation method of the Chinese medicine compound composition preparation includes the following steps:

[0033] (1) Take 15 grams of sun-dried ground, 15 grams of Salvia miltiorrhiza, 10 grams of Dan bark, 6 grams of Coptis, 10 grams of red peony root, and 15 grams of ghost arrow feathers. Use 8 times the amount of water to decoct 2 times, the first 1.5 hours. For the second time for 1 hour, combine the decoction liquid, filter, and concentrate to obtain a concentrated liquid for use;

[0034] (2) Take the concentrate obtained in step (1), add water, filter, and adjust the pH value to prepare an oral liquid. (Batch number: 001), the traditional Chinese medicine compound provided by the present invention focuses on clearing away heat and dredging co...

Embodiment 2

[0036] 1. The composition of raw materials of Chinese medicine compound:

[0037] 20 grams of raw land, 20 grams of salvia, 10 grams of paeonol, 8 grams of coptis, 10 grams of red peony, 20 grams of ghost arrow feathers.

[0038] 2. The preparation method of the Chinese medicine compound composition preparation includes the following steps:

[0039] (1) Take 20 grams of raw place, 20 grams of Salvia miltiorrhiza, 10 grams of Dan Bark, 8 grams of Coptis, 10 grams of Red Peony Root, and 20 grams of Ghost Arrow Feather, decoct 2 times with 6 times the amount of water, 1.5 hours each time, combine and decoct Boil the liquid, filter, and concentrate to obtain the concentrated liquid for use;

[0040] (2) Take the concentrated solution obtained in step (1) and add corn starch to mix uniformly, whole and dry to prepare Qinghuayure compound granules. (Batch number: 002)

Embodiment 3

[0042] 1. The composition of raw materials of Chinese medicine compound:

[0043] 10 grams of raw land, 10 grams of salvia, 5 grams of paeonol, 3 grams of coptis, 5 grams of red peony, 10 grams of ghost arrow feathers.

[0044] 2. The preparation method of the Chinese medicine compound composition preparation includes the following steps:

[0045] (1) Take 10 grams of raw place, 10 grams of Salvia miltiorrhiza, 5 grams of Danpi, 3 grams of Coptis chinensis, 5 grams of red peony root, and 10 grams of ghost arrow feathers. Use 8 times the amount of water to decoct twice for 1.5 hours each time. Liquid, filter and concentrate to obtain concentrated liquid for use;

[0046] (2) Take the concentrated solution obtained in step (1), freeze-dry, and sterilize to prepare Qinghuayure compound powder injection. (Lot Number: 003)

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Abstract

The invention discloses a traditional Chinese medicine capable of treating complications of diabetes and stagnant heat and application thereof. The traditional Chinese medicine is prepared with the following raw materials in parts by weight: 5-30 parts of radix rehmanniae, 5-30 parts of radix salviae miltiorrhizae, 5-15 parts of root bark of tree paeony, 2-10 parts of coptis root, 5-15 parts of root of common peony and 5-30 parts of euonymus alatus. The traditional Chinese medicine provided by the invention is a medicine prepared at a traditional Chinese proportion based on the theory of syndrome differentiation and treatment in accordance with the theory of the traditional Chinese medicine. Experiments show that the traditional Chinese medicine provided by the invention has a multi-level and multi-target combined effect, and can correct the sugar metabolism disorder, reduce the blood sugar, and improve the function of the pancreatic B cell and the insulin resistance; experiments also show that the traditional Chinese medicine provided by the invention can reduce the cardiomyopathy, thereby achieving the effect of well protecting the myocardium; and the traditional Chinese medicine provided by the invention also has the function of reducing the serum total cholesterol, the triglycercide and the anti-lipid peroxidation. Therefore, the traditional Chinese medicine provided by the invention is expected to be developed as a new generation drug used for treating the diabetes and complications of the diabetes and stagnant heat.

Description

Technical field [0001] The invention relates to a medicine, in particular to a traditional Chinese medicine compound with the effect of treating diabetes mellitus combined with blood stasis and heat and its application. Background technique [0002] Diabetes is a common and frequently-occurring disease worldwide, and has become the third largest disease after tumors and cardiovascular diseases. Diabetes and heat stasis are the main complications of diabetes. Diabetic heart disease is common clinically. Diabetic heart disease includes diabetes-specific cardiomyopathy, diabetes-related cardiac microvascular disease, macrovascular disease, cardiac autonomic neuropathy, etc. At the same time, it is often accompanied by non-specific coronary atherosclerotic heart disease and (or) hypertensive heart disease. Based on diabetes, it can be collectively referred to as diabetic heart disease. Compared with coronary atherosclerotic heart disease and cardiomyopathy that occur in non-diabetic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P3/06A61P3/10A61P9/00
Inventor 王旭周学平周仲瑛洪兵顾震宇
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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