Medicinal preparation for treating prostatitis

A pharmaceutical preparation, prostatitis technology, applied in the field of medicine, can solve the problems of sperm aggregation, decreased motility, decreased sperm count, etc.

Inactive Publication Date: 2010-12-01
北京卓越同舟药物研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 2. The secretion of prostatic fluid decreases, which leads to a decrease in semen volume and an increase in viscosity. It takes a long time for the fluid to be discharged, which affects the survival and vitality of sperm;
[0008] 4. Most of the bacteria infected by prostatitis are Escherichia coli and mycoplasma, which can cause sperm aggregation, decreased motility, decreased sperm count and increased deformed sperm;
But so far there is no new drug for the treatment of prostatitis prepared from the active ingredients extracted from psoralen

Method used

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  • Medicinal preparation for treating prostatitis
  • Medicinal preparation for treating prostatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Experimental animals: SD rats, 250-300g.

[0034] Experimental drugs and reagents: control drug ofloxacin tablets, product of Guangzhou Baiyunshan General Pharmaceutical Factory; Escherichia coli (hereinafter referred to as E. coli); nutrient agar medium.

[0035] Experimental method: male rats were selected, and they were randomly divided into negative control group (sham operation group, given equal volume of normal saline), model group (only given Escherichia coli, no drug treatment), positive control group (oxyfluorine Floxacin tablets, 0.1g kg-1), the experimental drug group. After 4 days of administration, surgical modeling was performed. The operation was performed under 10% urethane anesthesia. Under aseptic conditions, a median abdominal incision was made, and the bladder and seminal vesicles on both sides were raised to expose the dorsal lobe of the prostate attached to the inner side of the seminal vesicles. For contact stimulation, inject 1.4×10 7 coli nor...

Embodiment 2

[0060] A pharmaceutical preparation for treating prostatitis, the pharmaceutical raw material is psoralen 1g, prepared into 1000 units of tablets, capsules, granules or suppositories.

Embodiment 3

[0062] A pharmaceutical preparation for treating prostatitis, the drug raw material is psoralen 100g, prepared into 1000 units of tablets, capsules, granules or suppositories.

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PUM

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Abstract

The invention discloses a medicinal preparation for treating prostatitis, and the active ingredient of a natural medicament and a preparation method thereof. The medicinal preparation is characterized by comprising 90 to 97 percent of psoralen, wherein the psoralen contains two impurities, namely 3 to 8 percent of corylifolinin and less than 1 percent of bakuchiol; preferably, the medicinal preparation comprises 95 to 97 percent of psoralen, and the psoralen contains 3 to 4.5 percent of corylifolinin and less than 0.5 percent of bakuchiol; and more preferably, the medicinal preparation comprises 96 to 97 percent of psoralen, and the psoralen contains 3 to 4 percent of corylifolinin and less than 0.1 percent of bakuchiol. Pharmacodynamic experiments prove that the active ingredient has good effect of treating male erectile disorder.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical preparation for treating prostatitis. Background technique [0002] Prostatitis refers to systemic or local symptoms caused by acute and chronic inflammation caused by prostate specific and non-specific infection. Prostatitis can be divided into non-specific bacterial prostatitis, idiopathic bacterial prostatitis (also known as prostatitis), specific prostatitis (caused by Neisseria gonorrhoeae, Mycobacterium tuberculosis, fungi, parasites, etc.), non-specific granuloma Sexual prostatitis, prostatitis caused by other pathogens (such as viruses, mycoplasma, chlamydia, etc.), prostate congestion and prostatic pain. Since the seminal vesicle and the prostate are anatomically neighbors, the excretory duct of the seminal vesicle and the end of the vas deferens converge into the ejaculatory duct, which passes through the prostate and enters the urethra, so prostatiti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/37A61P13/08A61K31/192A61K31/7032A61K31/7048A61K31/343
Inventor 王爱民安晓雪周亚君
Owner 北京卓越同舟药物研究院有限公司
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