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Angelica sinensis blood enriching capsule and preparation method thereof

An angelica and capsule technology, which is used in capsule delivery, medical preparations containing active ingredients, blood diseases, etc., can solve the problems of not adapting to the rhythm of life and medication habits, difficult to store and carry decoction, difficult to produce and store, etc. Achieve good biocompatibility and degradability, improve application value, and facilitate portability and storage.

Active Publication Date: 2013-01-16
上海复旦复华药业有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Yet decoction is not easy to preserve and carry, and taking is also inconvenient, does not adapt to modern life rhythm and medication habit, urgently needs to improve
For "Danggui Buxue Decoction", one of the reasons why the current technology cannot fully reflect the essence of the ancient prescription is that it is very difficult to concentrate the medicinal liquid of Danggui Buxue Decoction and then dry it into a solid. A large number of sugars, esters and glycosides are difficult to dry into solids by traditional heating methods. On the other hand, the whole extract powder made from the co-decoction of angelica and astragalus has poor fluidity and strong hygroscopicity. Bonded into blocks, which brings difficulties to further production and storage

Method used

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  • Angelica sinensis blood enriching capsule and preparation method thereof
  • Angelica sinensis blood enriching capsule and preparation method thereof
  • Angelica sinensis blood enriching capsule and preparation method thereof

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preparation example Construction

[0027] The preparation method of the Angelica Buxue Capsule of the present embodiment comprises the steps:

[0028] (1) select 10 parts by weight of Angelica sinensis and 50 parts by weight of Radix Astragali to slice respectively, and wash the sliced ​​Angelica sinensis with wine to make wine-washed Angelica sinensis;

[0029] (2) mix the angelica washed with wine and astragalus, boil, cool, and filter to obtain the blood-enriching angelica liquid;

[0030] (3) Vacuum-low-temperature drying the angelica blood-tonifying medicinal liquid to make an angelica blood-tonifying dry extract, and then pulverizing the angelica blood-tonifying dry extract to obtain angelica blood-tonifying extract particles;

[0031] (4) Add medicinal gelatin powder to Danggui Buxue Extract Granules and mix evenly, then spray medicinal ethanol solution into the mixture of Danggui Buxue Extract Granules and medicinal gelatin powder to make it moist, and finally mix the medicine The mixture of Danggui Bu...

Embodiment 1

[0037] Preparation of Danggui Buxue Decoction: Take 60 grams of Danggui that complies with the quality standard of "Chinese Pharmacopoeia" (2005 edition), cut into thin slices of 1-2 mm, add 6 grams of rice wine, mix well, and place it in a sealed container for 2 hours, then put it in a pot and simmer over a low heat. Stir-fried until dry, sliced ​​into slightly burnt spots, then taken out, let cool, and made into wine-washed angelica. Take another 300 grams of Astragalus membranaceus that meets the quality standards of "Chinese Pharmacopoeia" (2005 edition), cut into thin slices of 2 to 4 mm, mix it with alcohol-washed angelica slices, add 3600 ml of drinking water, heat to boil, and keep it in a boiling state with a slow fire. When the liquid volume is 1800ml, stop heating, cool down to room temperature naturally, filter with double-layer natural color silk cloth, and discard the medicine residue to obtain "Danggui Buxue Decoction".

Embodiment 2

[0039] Preparation of Danggui Buxue Capsules: According to the above-mentioned preparation method of Danggui Buxue Decoction, Danggui blood-tonifying medicinal liquid is prepared, the medicinal liquid is poured on a stainless steel plate, put into a vacuum drying oven, decompressed, and gradually heated, and the temperature in the vacuum drying oven should not exceed 60°C until the medicinal liquid is dry, cool to room temperature, take it out, crush it into 40 mesh with a freezer pulverizer, and mix it with 1.2g of 80 mesh medicinal gelatin powder in a high-efficiency wet granulator, and the mixing speed of the high-efficiency wet granulator is The cutting speed is 200 rpm, the cutting speed is 1500 rpm, mixed for 5 minutes, and the mixing temperature is 19°C; 7.5g of 70% medicinal ethanol solution is sprayed, mixed for 5 minutes, and the mixing speed of the high-efficiency wet granulator is 200 rpm. Minutes, the cutting speed is 1500 rpm, after the mixing is finished, let it ...

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Abstract

The invention discloses an angelica sinensis blood enriching capsule and a preparation method thereof. The angelic sinensis blood enriching capsule consists of the following materials in parts by weight: 1000 parts of angelica sinensis blood enriching extract granules and 5-20 parts of gelatin granules, wherein the angelica sinensis blood enriching extract granules are granule extract prepared bypoaching, drying with vacuum and crushing 10 parts by weight of angelica sinensis and 50 parts by weight of astragalus. The preparation method comprises the steps of:10 parts by weight of angelica sinensis and 50 parts by weight of astragalus, poaching the angelica sinensis and the astragalus, drying with vacuum at low temperature, crushing, adding medicinal gelatin powder, evenly stirring the medicinal gelatin powder to the ground angelica sinensis and the ground astragalus, spraying medicinal ethanol solution,, drying the mixture, cooling, pelletting, and filling to obtain the capsules. Theangelica sinensis blood enriching capsule can be prepared completely in accordance with the traditional Chinese medicine theory, satisfies the demands of simpleness, convenience, easy storage and carrying of modern people, and has the advantages of good medical component retention, simple preparation method, convenient production operation, excellent extract granule fluidity, small hygroscopicity, difficult agglomeration, stable preparation quality and convenient storage, transportation, carrying and taking.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a preparation method of Danggui Buxue Capsules. Background technique [0002] Danggui Buxue Decoction, a traditional Chinese medicine prescription for invigorating qi and promoting blood, is mainly used to treat muscle heat, flushed face, thirsty desire to drink, large and weak pulse, weakness of heavy pressing, etc. Blood deficiency and yang floating fever syndrome; it is also used to treat women with blood deficiency during menstruation and postpartum Fever and headache; or ulcers that have not healed for a long time. According to the textual research of Nie Ke of Shandong College of Traditional Chinese Medicine, this prescription was first seen in "Discussion on Internal and External Injuries · Summer Injury to Stomach Qi" (AD 1247). It was created by Li Dongyuan, one of the four great masters of the Jin and Yuan Dynasties. To wash two money, use two c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K9/48A61K47/42A61P7/06
Inventor 任昉
Owner 上海复旦复华药业有限公司