Liquid bandage and preparation method

A liquid bandage and liquid technology, applied in blood diseases, pharmaceutical formulations, extracellular fluid diseases, etc., can solve the problems of easily damaged new skin, drug resistance of patients, and poor wound sealing, so as to avoid allergies and drug resistance, accelerate wound healing, and protect new tissue

Inactive Publication Date: 2010-12-22
SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the products used for wound care in the medical field, such as various band-aids, have the advantages of being cheap and convenient to use, but they also have some defects in use: the adhesive plaster used in traditional band-aids has poor air permeability, and the normal parts of the human body The secreted water vapor and sweat cannot penetrate this layer of adhesive tape, so it has a soaking effect on the local skin, and the specific performance is that the local skin is wrinkled; it is

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Its raw material composition and proportioning are:

[0040] Polyvinyl butyral 3.5g Dibutyl phthalate 2.0g

[0041] Methylcellulose 0.6g Glycerol 1.6g

[0042] Laurocaprazine 1.2g Chitosan 0.3g

[0043] 95% ethanol 35ml Wuweivine 184mL

[0044] Dracaena 184mL Frankincense 92mL

[0045] Myrrh 92mL Panax notoginseng 92mL

[0046] Its preparation method is:

[0047] 1. Weigh 3.5g of polyvinyl butyral, 0.3g of chitosan, measure 35mL of 95% ethanol, and stir while heating in a constant temperature water bath at 50°C until the film-forming substance is completely dissolved; add laurocaprolactone 1.2 g, 1.6 g of glycerol, 2.0 g of dibutyl phthalate and 0.6 g of methylcellulose were mixed and stirred evenly to obtain a film liquid. The stirring speed is 300-400 rpm.

[0048] 2. Grind 50g each of schisandra, dragon's blood, frankincense, myrrh, and Panax notoginseng, and pack them into bags for use; each use 150mL of 95% ethanol to reflux in a constant temperature water b...

Embodiment 2

[0061] Its membrane fluid composition and ratio are:

[0062] Polyvinyl butyral 3.7g Dibutyl phthalate 1.0g

[0063] Methylcellulose 0.4g Glycerol 1.6g

[0064] Laurocaprazine 1.2g Chitosan 0.3g

[0065] 95% ethanol 37ml Wuweivine 184mL

[0066] Dracaena 276mL Frankincense 92mL

[0067] Myrrh 92mL Panax notoginseng 92mL

[0068] Its preparation and performance testing methods are basically the same as in Example 1.

[0069] Compared with Example 1, the amount of polyvinyl butyral in Example 2 is reduced, so that the absorption of 5% ammonia water as tissue fluid and sweat analogue is greatly reduced, so that the waterproof performance is better, and the adhesion to the skin is also improved. The best; and the corresponding reduction in the amount of methyl cellulose and dibutyl phthalate makes up for the lack of absorption of ammonia water, and makes up for each other's impact on water resistance and skin adhesion. The liquid provided by this embodiment The effect of the...

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PUM

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Abstract

The invention discloses a liquid bandage and a preparation method. The liquid bandage comprises the following raw materials: polyvinyl acetal, dibutyl phthalate, methyl cellulose, glycerol, laurocapram, chitosan, 95% ethanol, securidaca inappendiculata, dragon blood, frankincense, myrrh and sanchi; the preparation method comprises the following steps: stirring and dissolving the polyvinyl acetal,the chitosan and the ethanol at a temperature of 5 DEG C, and adding the laurocapram, the glycerol, the dibutyl phthalate and the methyl cellulose to obtain film liquid; performing reflux extraction on the crushed securidaca inappendiculata, dragon blood, frankincense, myrrh and sanchi with ethanol at a temperature of 60 DEG C until the extracted liquid is colorless, filtering at a normal pressure and concentrating; and adding the concentrated solution of the securidaca inappendiculata, the dragon blood, the frankincense, the myrrh and the sanchi into the film liquid and mixing uniformly. Theliquid bandage is convenient to use and has high water resistance and air permeability, without sticking on clothes and cotton-padded mattress, causing anaphylaxis and drug resistance or being limited by the shape, size and location of the wound.

Description

technical field [0001] The invention relates to a preparation method of a liquid bandage, which is a medical dressing and belongs to the field of medical technology. Background technique [0002] At present, the products used for wound care in the medical field, such as various band-aids, have the advantages of being cheap, convenient and quick to use, but they also have some defects in use: the adhesive plaster used in traditional band-aids has poor air permeability, and the normal parts of the human body The secreted water vapor and sweat cannot penetrate this layer of adhesive tape, so it has a soaking effect on the local skin, and the specific performance is that the local skin is wrinkled; it is fixed on the wound through the adhesive layer, and the seal between the wound and the outside world is not good, so it is easy to make Dust or water seeps into the wound, making the wound infected and the scar too large; removal effort can easily destroy the new skin; in many wo...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61K36/889A61P7/04A61P29/00
Inventor 刘德荣范卫红刘芳
Owner SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING
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