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Preparation used for preventing and treating animal viral diseases

A technology for viral diseases and animals, applied in the direction of antiviral agents, medical preparations containing active ingredients, suppository delivery, etc., to achieve the effects of reducing stress, quick onset, and avoiding gastric acid and liver damage

Inactive Publication Date: 2011-01-05
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Reduce the poor palatability of drugs due to odor and other reasons

Method used

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  • Preparation used for preventing and treating animal viral diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: the preparation (1000 pills) of polymuscular cell anal suppository

[0030] 1. Prepare a sodium chloride-phosphate buffer solution with a pH of 6.5-7.5, and weigh an appropriate amount of Na 2 HPO 4 2H 2 O, NaH 2 PO 4 12H 2 Sodium chloride-phosphate buffer system prepared by mixing O and NaCl with water; preferably weighed NaH 2 PO 4 12H 2 O 0.262g, Na 2 HPO 4 2H 2 Dissolve O 3.895g and NaCl 8.768g in water respectively, mix well and dilute to 1000ml with water, the measured pH value should be 7.2±0.2;

[0031] 2. In two containers, take an appropriate amount of the above-mentioned buffer solution preheated to 30-50°C (preferably 45°C), add 0.5g of polyinosinic acid and 0.5g of polycytidylic acid respectively, and stir to dissolve Afterwards, keep warm in a water bath at 30-50°C (preferably 45°C) for 30 minutes, combine the two liquids in one of the containers, rinse the other container with a small amount of buffer, and add the washing solution...

Embodiment 2

[0037] Embodiment 2: Taking the anal suppository prepared by the above-mentioned process as an example, the preventive effect test of porcine reproductive and respiratory syndrome was carried out to further illustrate the prevention and treatment effect of the medicine of the present invention on animal viral diseases.

[0038] In selected pigs, elevated body temperature was found, mostly between 39.2°C and 42°C. Mental fatigue caused them to eat less. Suffering from pig runny nose, sneezing, coughing, increased eye secretions, conjunctivitis symptoms or accompanied by diarrhea, sometimes constipation, purple back of the ears, and plaques on the skin of the abdomen and extremities, which are purple red. Porcine Reproductive and Respiratory Syndrome was diagnosed. The non-affected pigs in this group were randomly divided into groups, with 7 pigs in each group. Give the medicine of the present invention, one pill at a time, and use it once every three days; the control group i...

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PUM

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Abstract

The invention relates to a compound preparation used for preventing and treating animal viral diseases. The compound preparation mainly comprises a polyinosinic acid-polycytidylic acid polymer and appropriate auxiliary materials. Polyinosinic-polytidylin acid has high-efficiency interferon induction and immune adjustment effects. A conventional polyinosinic-polytidylin acid preparation is widely used for preventing and treating human and animal viral diseases; and the preparation formulation is an injection, an eye drop and the like. The injection has the disadvantages of great stress, inconvenient use and the like. Therefore, in order to bring convenience to animal medication, the preparation is prepared into a rectal suppository which is suitable to be used for animals by special process treatment, and simultaneously provides a feasible way for industrial large-scale production and is suitable for popularization and application.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a polymuscular anal suppository for preventing and treating animal viral diseases and a preparation method thereof. Background technique [0002] Animal infectious diseases are the most serious diseases to the breeding industry, causing huge losses to the animal husbandry industry. It can not only cause the death of a large number of livestock, but also affect foreign trade. serious threat to human health. [0003] At present, the prevention and treatment of animal infectious diseases mainly adopts the principle of "prevention". Large-scale farms often mainly rely on the use of vaccines to prevent and control the occurrence of diseases. In addition, methods such as "all in, all out" are adopted to control the occurrence of diseases. However, it has been clinically found that in recent years, due to the continuous emergence of mutant strains and super-vir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/02A61K39/00A61K47/42A61K47/34A61P31/12A61K47/10
Inventor 夏雪林
Owner TIANJIN RINGPU BIO TECH
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