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Nanocomposite intervertebral fusion cage and preparation method thereof

A nano-composite material, intervertebral cage technology, applied in the direction of fixator, internal fixator, internal bone synthesis, etc., can solve the problems of increasing the brittle fracture of the intervertebral cage, uncontrollable degradation rate, unstable mechanical properties, etc. Achieve good bioactivity and biocompatibility, good toughness, and reduce stress shielding effects

Active Publication Date: 2011-04-27
SICHUAN GUONA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this product has the characteristics of poor bone conduction ability, uncontrollable degradation rate, and unstable mechanical properties.
The use of sintered hydroxyapatite increases the risk of brittle fracture of the intervertebral cage

Method used

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  • Nanocomposite intervertebral fusion cage and preparation method thereof
  • Nanocomposite intervertebral fusion cage and preparation method thereof
  • Nanocomposite intervertebral fusion cage and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0028] figure 1 with figure 2 The shown nano composite material intervertebral fusion cage of the present invention is composed of nano hydroxyapatite polyamide composite material. Its structure is in a nano-hydroxyapatite-polyamide 66 (or other medical polyamide component) composite matrix structure with a central hole 7 penetrating the upper and lower end faces, and the upper and lower end faces 2 are respectively in the direction of the end faces. It has a curved surface such as a moderately convex arc, and each is provided with a rough surface in the form of a tooth structure 1. On two opposite sides of the base structure, a side hole 3 communicating with the central hole 7 is respectively provided. At one end of the front and rear ends of the base structure in the use direction, a threaded clamping hole 6 is provided, and both sides of the outer hole are provided with a concave clamping structure 5 in a suitable form such as a groove. On both sides of the upper end surfa...

Embodiment 2

[0034] The corresponding injection mold of the intervertebral fusion cage is installed on a conventional plastic injection molding machine, and the nano-hydroxyapatite-polyamide 6 is used as the raw material. The injection molding operation parameters are set as follows: melt temperature 220℃ and injection temperature 225℃, injection pressure 90Mpa, injection speed 10mm / s, holding pressure 60Mpa(, holding pressure time 5s (adjustable within 3~10s) , The cooling time is 20s, the mold temperature is 100°C (adjustable within the range of 100-110°C), and the nanocomposite intervertebral fusion device can be obtained by removing the surface from the mold.

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Abstract

The invention discloses a nanocomposite intervertebral fusion cage and a preparation method thereof. The nanocomposite intervertebral fusion cage is provided with a substrate structure, the substrate structure passes through central holes of upper and lower end faces of the fusion cage, and the upper and lower end faces of the substrate structure are two rough surfaces in a dentiform structure; the side face of the substrate structure is provided with side holes communicated with the central holes; and the front end part or rear end part of the substrate structure is provided with a clamp hole with a thread along the application direction of the substrate structure, and the two sides of an external aperture of the clamp hole are provided with a concave clamp structure, wherein the two sides in an opposite angle direction of the upper end face or the lower end face of the substrate structure are respectively provided with a coplanar metal positioning structure, and an end part at which a non-threaded hole on the other end face of the substrate structure is arranged is provided with an antarafacial metal positioning structure. The nanocomposite intervertebral fusion cage is prepared through the steps of injecting molten nano-hydroxyapatite / polyamide composite materials into a moulding mould at a temperature of 220 to 280 DEG C and under the pressure of 80 to 130MPa, then carrying out cooling and moulding on the obtained product so as to obtain the intervertebral fusion cage. The nanocomposite intervertebral fusion cage has the advantages of excellent bioactivity, excellent biocompatibility and mechanical property matched with the human body, and capability of facilitating to determining the position and height of the nanocomposite intervertebral fusion cage implanted in an X-ray sheet.

Description

Technical field [0001] The invention relates to an internal fixation device for the spine, in particular an intervertebral fixation device for clinical thoracolumbar fusion surgery, and a preparation method thereof. Background technique [0002] Lumbar degenerative spondylolisthesis, segmental instability, intervertebral disc disease, low back pain caused by lumbar instability caused by traumatic spondylolisthesis, and limb motor sensory disturbances generally require lumbar fixation and fusion for non-surgical treatments. In recent years, lumbar interbody fusion cages have been widely used in lumbar fusion surgery. With the development of spine biomechanics and the wide application of lumbar interbody fusion, interbody fusion cages have developed rapidly and there are many types. [0003] Since the intervertebral fusion was used in clinical practice, the traditional technique using autologous three-sided cortical bone as the fusion medium has been widely used in clinical practice...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/70A61F2/44
CPCA61F2/44A61F2002/30001
Inventor 严永刚曹侠李鸿吕国玉杨爱萍宋跃明裴福兴肖嵩华蒋电明周跃权正学崔庚王潇罗琳
Owner SICHUAN GUONA TECH
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