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Extract of Chinese herb marsdenia tenacissima as well as preparation method and application thereof

A technology of clearing vine and extract, applied in the field of traditional Chinese medicine clearing vine extract and its preparation, can solve the problems of progressing to liver cirrhosis, and even a small number of people may have primary liver cancer, etc., to prevent leukopenia, improve Antioxidant, alleviating myelosuppression effect

Inactive Publication Date: 2011-04-27
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the treatment of hepatitis B, our country has made great achievements, and the infection rate of hepatitis B virus has also dropped rapidly, but in terms of absolute numbers, it is still huge. Even if calculated according to the current 7.18%, there are still nearly 9% of the population in our country. Tens of thousands of HBsAg carriers, some of these people are already chronic hepatitis B patients, some may have progressed to liver cirrhosis, and even a small number of people may have primary liver cancer

Method used

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  • Extract of Chinese herb marsdenia tenacissima as well as preparation method and application thereof
  • Extract of Chinese herb marsdenia tenacissima as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1: Preparation of Clearance Vine Extract

[0031] Weighing the raw material of the vines, crushing and sieving, adding 4 times the amount of ethanol with a concentration of 90%, and extracting by refluxing once for 1 hour each time, to obtain the vine extracts containing total phenolic acids and total saponins.

Embodiment 2

[0032] Example 2: Preparation of Clearance Vine Extract

[0033] Weigh the crude drug Clearing vine, pulverize and sieve, add 20 times the amount of ethanol with a concentration of 60%, reflux for 3 times, and extract for 2 hours each time to obtain a clearing vine extract containing total phenolic acids and total saponins.

Embodiment 3

[0034] Example 3: Preparation of Clearance Vine Extract

[0035] Weighing the raw drug Clearing vine, crushing and sieving, adding 6 times the amount of ethanol with a concentration of 75%, refluxing extraction for 2 times, each extraction for 2 hours to obtain a clearing vine extract containing total phenolic acids and total saponins.

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Abstract

The invention discloses an extract of Chinese herb marsdenia tenacissima as well as a preparation method and application thereof, belonging to the technical fields of extracts of Chinese herbs and preparation methods thereof. The extract containing total phenolic acid and total saponin which are effective parts of marsdenia tenacissima can be extracted by reflux with ethanol or can be prepared by separately extracting the extracts of the total phenolic acid and the extracts of the total saponin and mixing the extracts together. The extract of Chinese herb marsdenia tenacissima can be used for preparing medicines for resisting against hepatitis B virus, reducing transaminase level and regulating immunity. The extract of Chinese herb marsdenia tenacissima has the effect of protecting liver and reducing enzyme and certain protection effect on animal liver injury caused by CC14, and meanwhile, can improve non-specific immunity function in a proper dosage range.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extracts and a preparation method thereof, and particularly relates to a traditional Chinese medicine clearing vine extract and a preparation method and application thereof. Background technique [0002] The number of people with hepatitis B virus in the world is 350 million, and the number of people infected with hepatitis C has also reached 150 million. In my country, the hepatitis B infection rate is about 10%, and about 40 million people are infected with hepatitis C. The above data shows that the hepatitis C infection group is also very large and cannot be ignored. [0003] In the treatment of hepatitis B, my country has made great achievements, and the infection rate of hepatitis B virus has declined rapidly, but in absolute terms, it is still huge. Even at the current 7.18%, there are still nearly 9 There are more than 10 million HBV surface antigen carriers, and some ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P1/16A61P31/20
Inventor 刘峰群韩晋周旭张诗龙
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL