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Oral medicine for preventing and treating leukocytopenia caused by chemotherapy

A technology of medicine and traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve the problems of infection with blood-borne infectious diseases, limited clinical use, short survival time, recurrence and growth of cancer, and achieves the effects of low cost, not easy to fall back, and high efficiency.

Active Publication Date: 2012-12-26
南通好又鲜水产食品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The clinical use of glucocorticoids is limited due to their side effects and their possible promoting effect on some malignant tumors
[0006] Component blood transfusion, hematopoietic stem cell transplantation or support for severe bone marrow suppression, but there is a risk of infection of blood-borne infectious diseases, and the transfused blood cells have a short survival time due to rejection in the recipient and can promote cancer recurrence and growth possibility of

Method used

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  • Oral medicine for preventing and treating leukocytopenia caused by chemotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take the raw materials according to the following weight ratio:

[0031] Fairy Spleen 150g, Psoraleae 90g, Ligustrum lucidum 90g, Eclipta 90g, Caulis Spatholobus 150g, Polygonatum 150g, Astragalus 160g, Ginseng 90g, Poria cocos 100g, Atractylodes macrocephala 100g, Angelica 100g, Rehmannia glutinosa 100g, Rhizoma Chuanxiong 80g, red 80g of peony root, 30g of amomum, 100g of donkey-hide gelatin, 50g of roasted licorice, 50g of gallinaceous gold, 50g of fried malt, 50g of tangerine peel, and 50g of pinellia.

[0032] Preparation method: the above medicines are firstly crushed into coarse powder, and then made into 1000ml oral liquid through extraction, purification, concentration, sub-packaging, sterilization and other processes, 3 times a day, 20ml each time, for clinical application.

Embodiment 2

[0034] Take the raw materials according to the following weight ratio:

[0035] 3 parts of fairy spleen, 2 parts of psoralen, 3 parts of astragalus, 2 parts of raw ginseng, 2 parts of Atractylodes macrocephala, 2 parts of poria cocos, 2 parts of roasted licorice, 2 parts of angelica, 2 parts of Chuanxiong, 2 parts of red peony root, 2 parts of rehmannia glutinosa 2 parts of donkey-hide gelatin, 3 parts of Caulis Spatholobus, 3 parts of Polygonatum, 1 part of Chicken Negonia, 1 part of Fried Malt, 1 part of Pinellia, and 1 part of Tangerine Peel.

[0036] Production method: make the above-mentioned components into granules according to the production method of granules, 3 times a day, 9 grams each time, for clinical use.

Embodiment 3

[0038] 3 parts of fairy spleen, 2 parts of psoralen, 3 parts of astragalus, 2 parts of raw ginseng, 2 parts of Atractylodes macrocephala, 2 parts of poria cocos, 2 parts of roasted licorice, 2 parts of angelica, 2 parts of Chuanxiong, 2 parts of red peony root, 2 parts of rehmannia glutinosa 2 parts of donkey-hide gelatin, 3 parts of Caulis Spatholobus, 3 parts of Polygonatum, 1 part of Chicken Negonia, 1 part of Fried Malt, 1 part of Pinellia, and 1 part of Tangerine Peel.

[0039] Preparation method: make the above-mentioned components into liquid extract according to the preparation method of liquid extract, 3 times a day, 10 grams each time, for clinical use.

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Abstract

The invention discloses an oral medicine for preventing and treating leukocytopenia caused by chemotherapy, which is prepared from the following traditional Chinese medicines in parts by weight: 2-3 parts of herba epimedii, 1-2 parts of psoralea, 2-3 parts of astragalus root, 1-2 parts of sun-dried ginseng, 1-2 parts of bighead atractylodes rhizome, 2-3 parts of poria cocos, 1- 2 parts of prepared licorice, 1-2 parts of angelica, 1-2 parts of chuanxiong rhizome, 1-2 parts of red peony root, 1-2 parts of prepared rehmannia root, 1-2 parts of donkey-hide gelatin, 2-3 parts of spatholobus stem, -3 parts of rhizoma polygonati, 1-2 parts of chickens gizzard-membrane, 1-2 parts of fried malt, 1-1.5 parts of pinellia tuber and 1-1.5 parts of dried orange peel. The donkey-hide gelatin can be replaced by 0.5-1 part of antler glue. The oral medicine provided by the invention is a decoction, or can be prepared into an oral liquid, granules, a fluid extract or pill according to traditional methods. The oral medicine provided by the invention can be used for preventing and treating leukocytopenia caused by chemotherapy and can also be used for preventing and treating leukocytopenia caused by various other factors.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to an oral medicine suitable for preventing and treating leukopenia caused by chemotherapy. Background technique [0002] Radiotherapy and chemotherapy are two of the three major treatment methods for tumors. Both radiotherapy and chemotherapy can cause myelosuppression, especially chemotherapy is the most common. Clinically, leukopenia first appeared, which affected the smooth progress of chemotherapy, thereby affecting the curative effect of anti-tumor therapy. According to foreign literature reports, the treatment-related mortality rate related to IV degree myelosuppression hemogram in chemotherapy can reach 4%-21%. Clinically, the progress of chemotherapy is blocked due to cytopenia, which leads to a decrease in the efficacy of local tumor control, such as breast cancer, head and neck tumors, lung cancer and upper gastrointestinal tumors. Adverse reactions caused gr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P7/00A61K35/36A61K35/37A61K35/57
Inventor 耿平张光明张继鹏王征李建忠
Owner 南通好又鲜水产食品有限公司
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