Production method of pine pollen soft capsule for treating fatty liver

A production method and technology of pine pollen, which are applied in the directions of capsule delivery, medical raw materials from gymnosperm subphylum, digestive system, etc., can solve the problem that pine pollen resources are not well utilized, the comprehensive processing and utilization level is not high, and intensive processing It is suitable for long-distance transportation, long-term storage, and good sealing effect.

Active Publication Date: 2011-07-06
YANTAI NEW ERA HEALTH IND +1
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AI Technical Summary

Problems solved by technology

In contrast, although the development and research of pine pollen in my country has been carried out for more than ten years, and a large number of pine pollen products have appeared, the level of comprehensive processing and utilization is not high. The existing pine pollen products on the market have a single type and uneven quality. Not uniform, the degree of intensive processing is not high, export products are even rarer, and the precious pine pollen resources have not been well utilized

Method used

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Embodiment Construction

[0017] One, prepare the freeze-dried powder of pollen treatment fatty liver aqueous extract:

[0018] 1. Sorting pollen: remove impurities in pine pollen at room temperature.

[0019] 2. Breaking the wall: the pollen that has been removed is broken under the frequency of the grading motor at a frequency of 55-60 Hz and the air source pressure of 0.7-1.0 MPa.

[0020] 3. Soaking and ultrasonic treatment: Soak the pollen after the wall-breaking treatment in water at normal pressure and temperature, and treat it with ultrasonic waves for 20 to 40 minutes.

[0021] 4. Impurity removal:

[0022] Impurity removal: Centrifuge the ultrasonically treated material in a refrigerated centrifuge with a rotational speed of 10,000 to 16,000 rpm for 10 to 15 minutes to remove solid impurities and take the supernatant.

[0023] 5. Ultrafiltration: Pass the supernatant through a molecular sieve below 3000D at an ambient temperature of 1-5°C to separate water-soluble substances with a molecula...

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Abstract

The invention discloses a production method of a pine pollen soft capsule for treating fatty liver, relating to the technical field of production of health care soft capsules. The production method comprises the following steps of: performing air stream pulverization and wall breaking on pine pollen with impurities removed; soaking in water of normal pressure and temperature; performing ultrasonic treatment; centrifuging by a refrigerated centrifuge with the rotation speed of 10000-16000rpm, taking supernatant; separating the supernatant at the ambient temperature of 1-5 DEG C to obtain water soluble matters of pine pollen of which the molecular weight is smaller than 3000D; performing vacuum freeze drying on the water soluble matters of pine pollen to form lyophilized powder of pine pollen with the moisture content below 5%; evenly mixing the lyophilized powder of pine pollen with flax seed oil and lecithin; and gelatinating and pelleting to obtain the pine pollen soft capsule for treating fatty liver. The product disclosed by the invention has no side effect, high stability, oxidation resistance and high bioavailability, can cover up unpleasant odor and reduce irritation, and is convenient to take and quick to absorb.

Description

technical field [0001] The invention relates to the technical field of production of health-care soft capsules, in particular to a production method of soft capsules for treating fatty liver. Background technique [0002] The soft capsule dosage form is a new dosage form developed after tablets, hard capsules, injections, etc. It can quantitatively inject and encapsulate oily functional substances, functional substance solutions or functional substance powders in the film. Form sealed capsules of various sizes and shapes. Soft capsules have the characteristics of covering bad smell, reducing irritation, high stability, anti-oxidation, convenient taking, and high bioavailability. The advantages of soft capsules are that they can be directly absorbed after disintegration, fast absorption; accurate quantification; high bioavailability; small dosage; good stability of functional substances, not easy to oxidize and absorb moisture; good sealing, can cover the bad smell of drugs ...

Claims

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Application Information

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IPC IPC(8): A61K36/15A61K9/48A61P1/16A61K133/00
Inventor 周斌刘志河石丽花叶满红王桐于建伟鞠东尹利端李明乔强
Owner YANTAI NEW ERA HEALTH IND
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