Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Delivery system for novel bioresorbable slide fastener scaffold

A biological stent, sliding button technology, applied in stent, medical science, prosthesis and other directions, to prevent stent displacement

Inactive Publication Date: 2011-08-24
XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to solve the delivery problem of this new type of stent, and provide a transcatheter delivery device. The device adopts the method of combining the outer sleeve and the balloon catheter, so that the outer layer of the stent will not bounce off before the expansion of the stent. The stent can be positioned accurately, and the stent can be fully expanded by dilating the balloon

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Delivery system for novel bioresorbable slide fastener scaffold
  • Delivery system for novel bioresorbable slide fastener scaffold
  • Delivery system for novel bioresorbable slide fastener scaffold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] In vitro simulating blood vessels, the new sliding buckle stent delivery device is used to simulate the delivery of polycaprolactone (PCL) edge sliding buckle stents to observe the delivery and release of the stent.

[0026] 1. Materials and methods:

[0027] Materials: Polycaprolactone (PCL) edge sliding buckle type bracket 20*8mm 10 each, 6cm diameter rubber hose, bracket delivery device and pressure pump.

[0028] method:

[0029] 1. First use a pressure pump to suck the balloon of the delivery device into negative pressure, then withdraw the outer sheath, curl and wrap the slide stents on the delivery device balloon, and then push the outer sheath forward to the cone to wrap it. Bracket.

[0030] 2. Insert the stent delivery device into the target site of the artificial blood vessel along the guide wire, expand and release the stent in 12atm*30 seconds.

[0031] 3. Re-suction the balloon to a negative pressure, then withdraw the balloon.

[0032] 2. Observation indicators:

[0...

Embodiment 2

[0042] In vitro simulating blood vessels, a new sliding buckle stent delivery device was used to simulate the delivery of poly-dioxanone (PDO) edge sliding buckle stents to observe the delivery and release of the stent.

[0043] 1. Materials and methods:

[0044] Materials: Poly-dioxanone (PDO) edge sliding buckle stents 20*8mm, 10 pieces each, 6cm diameter rubber hose, stent delivery device and pressure pump.

[0045] method:

[0046] 1. First use a pressure pump to suck the balloon of the delivery device into negative pressure, then withdraw the outer sheath, curl and wrap the slide stents on the delivery device balloon, and then push the outer sheath forward to the cone to wrap it. Bracket.

[0047] 2. Insert the stent delivery device into the target site of the artificial blood vessel along the guide wire, expand and release the stent in 12atm*30 seconds.

[0048] 3. Re-suction the balloon to a negative pressure, then withdraw the balloon.

[0049] 2. Observation indicators:

[0050] ...

Embodiment 3

[0059] In the experimental porcine iliac artery blood vessel, a new sliding buckle stent delivery device was used to deliver a polycaprolactone (PCL) edge sliding buckle stent to observe the delivery and release of the stent.

[0060] 1. Materials and methods

[0061] Materials: 10 pigs of 25Kg, puncture needle, guide wire, 7F sheath, Onipex, chloramphenone, heparin, stent delivery device, pressure pump and GE-2005 angiography instrument.

[0062] Sample content: 10 pigs, 15 PCL slide brackets 20*8mm.

[0063] Specific steps and methods: (see Image 6 , 7 ,8)

[0064] 1. Anesthetize the pig with 10mg / Kg of ketanone, intubate the trachea, monitor the electrocardiogram, conventionally sterilized sterile towels, puncture the left carotid artery, and insert a 9F sheath.

[0065] 2. Perform angiography of the left and right iliac arteries and choose to implant the blood vessel. The diameter of the stent is required to be 25% larger than the diameter of the blood vessel.

[0066] 3. Use a press...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a transcatheter delivery device for delivering a novel slide fastener scaffold to a narrow lumen. The device consists of an outer sleeve, an inner sheath and a sacculus catheter, wherein the outer sleeve is provided with a near end, a far end and an inner cavity extending between the two ends; the inner sheath is also provided with a near end, a far end and an inner cavity extending between the two ends; the outer diameter of the inner sheath ensures that the inner sheath is slidably inserted into the cavity of the outer sleeve; the sacculus catheter is also provided with a near end, a far end and an inner cavity; the outer diameter of the sacculus catheter ensures that the sacculus catheter is slidably inserted into the cavity of the inner sheath; the far end of the sacculus catheter is provided with a sacculus, and the length and diameter of the sacculus can be selected according to the requirement of the scaffold; two ends of the sacculus are respectively provided with a metal marker for assisting positioning the scaffold; the far end of the sacculus is attached with a tapered body which can prevent the scaffold from sliding to the far end, and the near end part of the tapered body can be inserted into the outer sleeve, so that the tapered body and the outer surface of the outer sleeve are kept on the same horizontal plane; and the inner sheath is slightly shorter than the sacculus catheter, and directly reaches the near end of the sacculus of the sacculus catheter, so the scaffold can be prevented from sliding to the near end.

Description

Technical field: [0001] This patent relates to a delivery device for implanting a non-self-expanding sliding buckle stent across the lumen through a catheter, which is used to expand the narrow parts of the blood vessel, trachea, esophagus, urethra, bile duct and other organs. technical background: [0002] In the field of interventional therapy, for the stenosis of blood vessels, trachea, esophagus, urethra, biliary tract and other organs, stents are usually implanted to expand the stenosis and effectively maintain the smoothness of the lumen. The stent is introduced into the lumen in the unexpanded state and positioned at the stenosis, then expanded and placed there. [0003] Traditionally, stents can be divided into two types according to their expansion mechanism: one is a self-expanding stent called self-expanding stent. This kind of stent material is mainly a shape memory alloy and polymer; the stent is compressed in advance. When the inner and outer catheters of the inserte...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/84A61F2/958
Inventor 孙锟孙康冯其茂姜闻博窦红静李伟
Owner XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products