Delivery system for novel bioresorbable slide fastener scaffold
A biological stent, sliding button technology, applied in stent, medical science, prosthesis and other directions, to prevent stent displacement
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Embodiment 1
[0025] In vitro simulating blood vessels, the new sliding buckle stent delivery device is used to simulate the delivery of polycaprolactone (PCL) edge sliding buckle stents to observe the delivery and release of the stent.
[0026] 1. Materials and methods:
[0027] Materials: Polycaprolactone (PCL) edge sliding buckle type bracket 20*8mm 10 each, 6cm diameter rubber hose, bracket delivery device and pressure pump.
[0028] method:
[0029] 1. First use a pressure pump to suck the balloon of the delivery device into negative pressure, then withdraw the outer sheath, curl and wrap the slide stents on the delivery device balloon, and then push the outer sheath forward to the cone to wrap it. Bracket.
[0030] 2. Insert the stent delivery device into the target site of the artificial blood vessel along the guide wire, expand and release the stent in 12atm*30 seconds.
[0031] 3. Re-suction the balloon to a negative pressure, then withdraw the balloon.
[0032] 2. Observation indicators:
[0...
Embodiment 2
[0042] In vitro simulating blood vessels, a new sliding buckle stent delivery device was used to simulate the delivery of poly-dioxanone (PDO) edge sliding buckle stents to observe the delivery and release of the stent.
[0043] 1. Materials and methods:
[0044] Materials: Poly-dioxanone (PDO) edge sliding buckle stents 20*8mm, 10 pieces each, 6cm diameter rubber hose, stent delivery device and pressure pump.
[0045] method:
[0046] 1. First use a pressure pump to suck the balloon of the delivery device into negative pressure, then withdraw the outer sheath, curl and wrap the slide stents on the delivery device balloon, and then push the outer sheath forward to the cone to wrap it. Bracket.
[0047] 2. Insert the stent delivery device into the target site of the artificial blood vessel along the guide wire, expand and release the stent in 12atm*30 seconds.
[0048] 3. Re-suction the balloon to a negative pressure, then withdraw the balloon.
[0049] 2. Observation indicators:
[0050] ...
Embodiment 3
[0059] In the experimental porcine iliac artery blood vessel, a new sliding buckle stent delivery device was used to deliver a polycaprolactone (PCL) edge sliding buckle stent to observe the delivery and release of the stent.
[0060] 1. Materials and methods
[0061] Materials: 10 pigs of 25Kg, puncture needle, guide wire, 7F sheath, Onipex, chloramphenone, heparin, stent delivery device, pressure pump and GE-2005 angiography instrument.
[0062] Sample content: 10 pigs, 15 PCL slide brackets 20*8mm.
[0063] Specific steps and methods: (see Image 6 , 7 ,8)
[0064] 1. Anesthetize the pig with 10mg / Kg of ketanone, intubate the trachea, monitor the electrocardiogram, conventionally sterilized sterile towels, puncture the left carotid artery, and insert a 9F sheath.
[0065] 2. Perform angiography of the left and right iliac arteries and choose to implant the blood vessel. The diameter of the stent is required to be 25% larger than the diameter of the blood vessel.
[0066] 3. Use a press...
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