Drug sustained release agent, adsorbent, functional food, mask, and adsorptive sheet

A technology of adsorbents and sustained-release agents, which is applied in the fields of drug sustained-release agents, adsorbents, functional foods, masks and absorbent sheets, and can solve the problems of patients with large physical and mental burdens

Inactive Publication Date: 2011-08-24
SONY CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, hemodialysis not only requires special equipment and technicians but also imposes a great physical and / or mental burden on the patient

Method used

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  • Drug sustained release agent, adsorbent, functional food, mask, and adsorptive sheet
  • Drug sustained release agent, adsorbent, functional food, mask, and adsorptive sheet
  • Drug sustained release agent, adsorbent, functional food, mask, and adsorptive sheet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Example 1 relates to the drug sustained-release preparations according to the first to third embodiments of the present invention. In Example 1, first, a porous carbon material was produced based on the method described below.

[0068] Using monodisperse spherical particles of silica (trade name: SEAHOSTAR KE) manufactured by Nippon Shokubai Co., Ltd. or spherical particles of silica (trade name: SNOWTEX) manufactured by Nissan Chemical Industries, Ltd., prepared with a solid content Aqueous monodisperse silica colloidal suspensions in aqueous solutions having a concentration of 3 to 40 wt %. Incidentally, the diameter of the colloidal particles is in the range of 6 nm to 1 μm. The monodisperse silica colloidal suspension aqueous solution was poured into an SPC filter holder (manufactured by Shibata Scientific Technology Ltd.) having a diameter of 30 mm in which a filter cloth was placed, and suction filtration under vacuum was performed using an aspirator . Incident...

Embodiment 2

[0081] Example 2 relates to the adsorbents for adsorbing organic substances thereon according to the first to third embodiments of the present invention, the adsorbents for medical use according to the first to third embodiments of the present invention, and the adsorbents according to the present invention The adsorbent for oral administration of the first to third embodiments. In Example 2, porous carbon material D, porous carbon material E, porous carbon material F, porous carbon material G, and porous carbon material H were produced based on the same method as described in Example 1. Incidentally, the porous carbon material D, the porous carbon material E, and the porous carbon material F were subjected to nitric acid treatment as a chemical treatment, while the porous carbon material F and the porous carbon material G were subjected to activation treatment by using water vapor. Table 1 lists the carbonization temperature, the presence or absence of nitric acid treatment, ...

Embodiment 3

[0159] Example 3 relates to adsorbents for adsorbing allergens thereon according to the first to third embodiments of the present invention. In Example 3, the samples of Examples 2-3B were used as porous carbon materials (see Table 1). In addition to this, as a reference example, the sample of Reference Example 2-1 was used (see Table 2). For the samples of Example 2-3B and Reference Example 2-1, the allergen (Der p 1) caused by the mite and the allergen caused by the pollen of Japanese cedar (Cry j 1) per gram of the sample were measured adsorption capacity. The measurement of the adsorption amount was basically carried out by the same method as in Example 2. Der p 1 has a molecular weight of 36,000 to 40,000, while Cry j 1 has a molecular weight of 50,000. The adsorption amount on the sample of Example 2-3B in the case where the adsorption amount on the sample of Reference Example 2-1 is regarded as "1" is shown in Table 21 below. Therefore, it can be seen that the adsor...

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Abstract

Provided is a drug sustained release agent comprising a carbon material (porous carbon material) having an inverted opal structure. The drug sustained release agent comprises a porous carbon material having a surface area of 3 x 102 m2 / gram or greater wherein spherical pores having an average diameter of 1 x 10-9 m to 1 x 10-5 m are three-dimensionally arranged; a porous carbon material wherein pores are visibly arranged in a pattern corresponding to a crystal structure; or a porous carbon material wherein pores are visibly arranged at the surface of a pattern corresponding to the (111) face orientation of a face-centered cubic structure.

Description

Technical field [0001] The present invention relates to a drug sustained release agent (drug sustained release agent) with porous carbon material, an adsorbent with porous carbon material, and functional foods, masks (mask) and adsorbent sheets using such adsorbent. (Adsorption sheet). Background technique [0002] In recent years, carbon materials with various nanostructures, such as carbon materials with regular (ordered) fine structures of carbon nanotubes, carbon nanohorns, zeolites, mesoporous silica, etc., have attracted great attention. In addition, there is a so-called inverse opal structure synthesized by using a colloidal crystal body composed of monodisperse silica particles, polystyrene particles, etc. as a mold (casting mold). Materials have also attracted attention. To date, materials with an inverted opal structure composed of carbon, titanium dioxide, silica, tin oxide, polymer materials, etc. have been reported, and their various application possibilities ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/04A61K9/70A61K31/192A62B18/02A62B23/02B01J20/20B01J20/28C01B31/02A23L5/20
CPCB01J20/28095A61K9/143B01J20/20A61K31/192A62B23/025B01J20/28057C01B31/00B01J20/28078B01J20/28033C01B32/00Y10T428/2982A61P29/00A61P39/02
Inventor 田畑诚一郎山田心一郎堀江毅野口勉
Owner SONY CORP
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