External application medicinal composition for treating leukoplakia vulvae and preparation method thereof

A technology for external application of drugs and vulvar leukoplakia, which is applied in the directions of drug combinations, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve the problems of complicated operation, short local residence time of fumigation and washing agents, and it is difficult for active ingredients to reach the vulva.

Active Publication Date: 2011-10-05
扬中市检验检测中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the oral medicine is absorbed through the intestines and stomach, it is difficult for the active ingredients to reach the vulva, and the efficacy of the medicine is greatly reduced, affecting the therapeutic effect, so it is impossible to completely cure leukoplakia
There are also reports on dosage forms for external use, such as the Kunyangning (Salvia miltiorrhiza, Cnidium chinensis, white moss bark, psoralen, fairy Spleen each 15g) Fumigation and washing after 24 hours of topical application of medicated pads to treat this disease, but the operation of medicated pads and fumigation is cumbersome, the local residence time of fumigation and washing agents is short, the efficacy cannot be sustained, and it is inconvenient to use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1, raw material drug weight ratio: 8 parts of Cortex Moutan, 8 parts of Fangfeng, 8 parts of Baibu, 8 parts of pine needles, 8 parts of rosin powder, 4 parts of peach gum, 1 part of scallion white, 14 parts of flax oil.

Embodiment 2

[0024] Example 2, the weight ratio of raw materials: 12 parts of Cortex Moutan, 12 parts of Fangfeng, 12 parts of Baibu, 12 parts of pine needles, 12 parts of rosin powder, 6 parts of peach gum, 1 part of scallion, and 20 parts of flax oil.

Embodiment 3

[0025] Example 3, the weight ratio of raw materials: 10 parts of Cortex Moutan, 10 parts of Fangfeng, 10 parts of Baibu, 10 parts of pine needles, 10 parts of rosin powder, 5 parts of peach gum, 1 part of scallion white, and 16 parts of flax oil.

[0026] Chinese medicine of the present invention can be prepared by following method:

[0027] (1) Wash, dry and pulverize Moutan bark, Fangfeng, Baibu and pine needles, and pass through a 100-mesh sieve to form a mixture for later use;

[0028] (2) Heat the sesame oil to 200°C~220°C, add the white scallions one by one to fry, take out the scallion residue, filter the oil, heat to 200°C~220°C, put in the mixture produced in step 1, and stir evenly. After heating for 10 to 15 minutes, filter the oil, heat to 80°C to 100°C, add rosin powder and peach gum, continue to stir, boil until dripping into beads, spray cold water on the surface to remove water poison, cool to room temperature and separate Just bottle it.

[0029] The ingredi...

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PUM

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Abstract

The invention discloses an external application medicinal composition for treating leukoplakia vulvae and a preparation method thereof, which are used for solving the problem of the treatment of leukoplakia vulvae. The external application medicinal composition is characterized by containing the following raw medicaments in parts by weight: 8-12 parts of root-bark of peony, 8-12 parts of ledebouriella root, 8-12 parts of stemona root, 8-12 parts of pine needle, 8-12 parts of colophony powder, 4-6 parts of peach tree glue, 1 part of fistrlar onion and 14-20 parts of siritch. The preparation method of the medicinal composition comprises the following steps of: frying the fistrlar onion in the siritch; filtering oil-bearing materials; adding the root-bark of peony, the ledebouriella root, the stemona root and the pine needle; filtering with oil; adding the colophony powder and the peach tree glue; stirring and decocting; removing infectious water; and performing cooling and split charging. As proved by clinical trial, the external application medicinal composition has the characteristics of good healing effect and high safety when being used for treating leukoplakia vulvae, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an external pharmaceutical composition for treating leukoplakia and a preparation method thereof. Background technique [0002] Leukoplakia, also known as white lesions of the vulva, refers to the localized or diffuse white plaques on the skin of the genitals of women, which can spread to the inner sides of the lower limbs, the perineum, and the anus, but rarely invade the urethra and vestibule. It is a chronic vulva. malnutrition disease. The disease can occur at any age, in various stages of women: childhood, adolescence, menopause and old age have been reported, but menopause around the age of 50 is in the majority, and the course of the disease varies in length, and the elderly can reach decades. The etiology is unclear, but it may be related to systemic factors, such as diabetes and endocrine disorders. Symptoms include genital itching, dry skin, hypertrophy and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P17/00A61K36/904
Inventor 栾艳邢海燕张引民
Owner 扬中市检验检测中心
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