The preparation method of total paeoniflorin

Abstract

The invention provides a preparation method of peony general glycoside, which comprises the following steps: soaking radix paeoniae alba or red paeonia in 2-10 times (weight) of hydrophilic solvent, wherein the hydrophilic solvent is water or a water solution containing less than 30% of methanol, ethanol, propanol and isopropanol; after soaking, percolating at low temperature of 5-40 DEG C; and concentrating the percolate, filtering to obtain the extracting solution, and passing the extracting solution through macroporous resin. The transfer rate of penoniflorin and peony Albiflorin is 85-90%, and the purity of the peony general glycoside extract is high.

Description

technical field

[0001] The invention relates to a method for preparing total glycosides of paeoniflorin, which belongs to the field of traditional Chinese medicines. technical background

[0002] Total paeoniflorin is a general term for a class of active ingredients of traditional Chinese medicine that were first isolated and discovered from peonies, so this type of monoterpene glycosides is called total paeoniflorin. There are more than ten kinds of paeoniflorin, paeoniflorin, hydroxypaeoniflorin, benzoylpaeoniflorin, paeoniflorinone, paeoniflorin and paeoniflorin R1. A variety of Chinese medicinal materials contain such ingredients, but the types and contents are not the same. Radix Paeoniae Rubra mainly contains paeoniflorin, and the content of paeoniflorin is less or not contained; The content of lactone glycosides is high; besides paeoniflorin, Moutan cortex also contains benzoylhydroxypaeoniflorin. Total paeoniflorin has strong pharmacological activities, mainly anti...

Images