Perfusion agent for treating cow endometritis, and preparation method thereof

A technology for endometritis and perfusion agent, applied in the direction of anti-inflammatory agents, non-central analgesics, synthetic active ingredients of polymeric materials, etc., can solve the problems of slow effect, bacterial resistance, low curative effect, etc. Good release, little effect on pH value, strong bactericidal effect

Active Publication Date: 2012-12-19
ZHENGZHOU BARY ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the past, there were many problems in the treatment of cow endometritis with antibiotics or traditional Chinese medicine. The simple use of antibiotics can easily cause bacterial resistance. The treatment effect of traditional Chinese medicine alone is slow, and the curative effect is significantly lower than that of antibiotics.

Method used

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  • Perfusion agent for treating cow endometritis, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A perfusate for the treatment of endometritis in dairy cows, the constituents and the contents of each component per 100L of the perfusate are:

[0019] Povidone-iodine 5kg;

[0020] ice flakes 5kg;

[0021] Sodium carboxymethyl cellulose 0.3kg;

[0022] Add polyethylene glycol-400 to 100L.

[0023] A preparation method for the perfusion agent for the treatment of dairy cow endometritis, its steps are as follows:

[0024] (1) Weigh povidone-iodine, borneol, and suspending agent respectively, and mix well to obtain mixture I, which is set aside;

[0025] (2) Take 40L of polyethylene glycol-400, add it to the mixture I, and stir while adding it to obtain a thick slurry mixture. After stirring evenly, add it to a grinder and grind it twice to make the emulsification fineness of the drug mixture reach 200μm. Obtain mixture II;

[0026] (3) Continue to add polyethylene glycol-400 to the mixture II until the preparation volume is 100L, stir evenly, and divide into packag...

Embodiment 2

[0028] A perfusate for the treatment of endometritis in dairy cows, the constituents and the contents of each component per 100L of the perfusate are:

[0029] Povidone-iodine 8kg;

[0030] ice flakes 8kg;

[0031] Sodium carboxymethyl cellulose 0.2kg;

[0032] Add polyethylene glycol-400 to 100L.

[0033] A preparation method for the perfusion agent for the treatment of dairy cow endometritis, its steps are as follows:

[0034] (1) Weigh povidone-iodine, borneol, and suspending agent respectively, and mix well to obtain mixture I, which is set aside;

[0035] (2) Take 50L of polyethylene glycol-400, add it to the mixture I, and stir while adding to obtain a thick slurry mixture. After stirring evenly, add it to a grinder and grind it twice to make the emulsification fineness of the drug mixture reach 200μm. Obtain mixture II;

[0036] (3) Continue to add polyethylene glycol-400 to the mixture II until the preparation volume is 100L, stir evenly, and divide into packages....

Embodiment 3

[0038] A perfusate for the treatment of endometritis in dairy cows, the constituents and the contents of each component per 100L of the perfusate are:

[0039] Povidone-iodine 10kg;

[0040] ice flakes 10kg;

[0041] Sodium carboxymethyl cellulose 0.5kg;

[0042] Add polyethylene glycol-400 to 100L.

[0043] A kind of preparation method of the perfusion agent for the treatment of cow endometritis, its steps are as follows:

[0044] (1) Weigh povidone-iodine, borneol, and suspending agent respectively, and mix well to obtain mixture I, which is set aside;

[0045] (2) Take 60L of polyethylene glycol-400, add it to the mixture I, and stir while adding to obtain a thick slurry mixture. After stirring evenly, add it to a grinder and grind it twice to make the emulsification fineness of the drug mixture reach 200μm. Obtain mixture II;

[0046] (3) Continue to add polyethylene glycol-400 to the mixture II until the preparation volume is 100L, stir evenly, and divide into packag...

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Abstract

The invention relates to a perfusion agent for treating cow endometritis, and further relates to a preparation method for the perfusion agent. Components of each 100 L of the perfusion agent comprise: 5-10 kg of povidone iodine; 5-10 kg of borneol; 0.1-0.5 kg of a suspending agent, the balance of polyethylene glycol-400. The perfusion agent is prepared through the following method: (1) respectively weighing the povidone iodine, the borneol and the suspending agent, then uniformly mixing to obtain a mixture I for later use; (2) adding 40-60 L of the polyethylene glycol-400 to the mixture I while stirring; after uniformly stirring, placing the resulting mixture containing the polyethylene glycol-400 in a grinder to carry out grinding for twice until the drug emulsion fineness is 200 mum to obtain a mixture II; (3) further adding the polyethylene glycol-400 to the mixture II until the total volume is 100 L, uniformly stirring and packing. According to the present invention, the perfusionagent adopts the combination method of the traditional Chinese drug and the western medicine, provides a significant therapeutic effect for the cow endometritis; and the drug resistance is difficult to be generated and the perfusion agent is easy to be used.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and in particular relates to a perfusion agent for treating cow endometritis and a preparation method thereof. Background technique [0002] The main cause of cow endometritis is the infection of pathogenic microorganisms. Due to the different feeding and management conditions of dairy farms, the types of pathogenic microorganisms that cause endometritis in dairy cows are also different. There are many kinds of bacteria that cause endometritis, and single infection and mixed infection exist at the same time. Studies have shown that the main pathogenic bacteria that cause cow endometritis are Staphylococcus aureus, Escherichia coli, Streptococcus, Pseudomonas aeruginosa and so on. [0003] In the past, there were many problems in the treatment of cow endometritis with antibiotics or traditional Chinese medicine. The simple use of antibiotics could easily lead to bacterial resistance...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/79A61K31/045A61P15/00A61P31/04A61P29/00
Inventor 郭玉凡陈盟张宁周衡王佳伟王喜平
Owner ZHENGZHOU BARY ANIMAL PHARMA
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