Manufacturing method of ceramide generation accelerator and/or glucosylceramide generation accelerator

Abstract

The invention provides a manufacturing method of a ceramide generation accelerator and / or a glucosylceramide generation accelerator, wherein Candida microorganisms are cultured in a culture medium containing beam dregs and saccharides, and the ceramide generation accelerator and / or the glucosylceramide generation accelerator are / is obtained from an obtained supernatant. According to the manufacturing method disclosed by the invention, by utilization of specific microorganisms and byproducts, namely the bean dregs, of the food processing industry and the like as a main raw material of the culture medium, the ceramide generation accelerator and / or the glucosylceramide generation accelerator can be acquired at low cost and high efficiency.

Description

technical field

[0001] The present invention relates to a method for producing a ceramide and / or glucosylceramide production promoter capable of promoting the production of ceramide and / or glucosylceramide in the skin by using specific microorganisms and using bean dregs, a by-product of the food processing industry, etc., as the main raw material of a culture medium . Background technique

[0002] Ceramide, one of the sphingolipids, exists in the stratum corneum of the skin and accounts for about 50% of the intercellular lipids in the stratum corneum. Sphingolipid is a general term for complex lipids having a sphingosine skeleton. Glucosylceramide is a kind of sphingolipid formed by binding glucose to ceramide. The ceramide synthesized by epidermal cells is temporarily stored in the form of glucosylceramide or sphingomyelin; it is then excreted outside the cell, where glucocerebrosidase (Glucocerebrosidase) and sphingomyelinase (Sphingomyelinase) Under the action of cera...

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