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Application of sargassan to preparation of medicament for preventing and treating urinary calculus

A technology of sargassum polysaccharides and urinary calculi, which is applied in the application field of medicine, can solve problems that have not been reported, and achieve the effect of broadening the use

Inactive Publication Date: 2012-06-13
SHANGHAI OCEAN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But there is no report about the application of Sargassum polysaccharides in the preparation of medicines for preventing and treating urinary calculi

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  • Application of sargassan to preparation of medicament for preventing and treating urinary calculus
  • Application of sargassan to preparation of medicament for preventing and treating urinary calculus
  • Application of sargassan to preparation of medicament for preventing and treating urinary calculus

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Embodiment Construction

[0023] The specific embodiments provided by the present invention will be described in detail below in conjunction with the accompanying drawings.

[0024] The invention uses sargassum as raw material, extracts polysaccharide from sargassum by hot water extraction method, removes protein and pigment with trichloroacetic acid, and then dries to obtain sargassum polysaccharide. Specific preparation steps: take 100 grams of Sargassum powder, add 4500ml of water, extract at 60°C and ultrasonic for 45 minutes, filter, concentrate the filtrate to 500ml, add 95% ethanol to make the total concentration of ethanol reach 80%, Stand overnight, centrifuge at 8000r / min for 10min, dissolve the obtained precipitate with water to 100ml, then add 1 times of trichloroacetic acid to remove protein, remove protein for 2 hours, then centrifuge for 15min at 8000r / min, remove the precipitate Finally, collect the supernatant, adjust the pH value to 4-5, add 6%-7% hydrogen peroxide for decolorization,...

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Abstract

The invention relates to an application of sargassan to the preparation of a medicament and a health-care food for preventing and treating urinary calculus. The application has the advantage that: according to the research of the application, a scientific basis is laid for the development of a natural antioxidant factor, a health-care food and a medicament for preventing and treating urinary calculus by using sargassan, and certain theoretical significance and clinical application value are achieved. Due to the adoption of the application, an important theoretical basis is provided for the development and application of the sargassan to the prevention and treatment of urinary calculus, the use of sargasso is widened, a thinking model is provided for the research of other marine algae or marine organisms, and a novel natural biomaterial is provided for the research of prevention and treatment of the urinary stone simultaneously.

Description

technical field [0001] The invention relates to the fields of medicines and health care products, in particular to the application of sargassum polysaccharides in the preparation of medicines for preventing and treating urinary calculus. Background technique [0002] The incidence and recurrence rate of kidney stones are high, among which calcium oxalate stones account for more than 80% of kidney stones. Urinary calculus is the product of pathological mineralization in organisms, and it is a common and frequently-occurring disease worldwide, and its incidence is on the rise. The disease is prone to recurrence after treatment, and the recurrence rate is 50% in 10 years. Although great progress has been made in surgical treatment, its morbidity and recurrence rate remain high, so various studies on urolithiasis have been paid more and more attention. [0003] In view of the high incidence and recurrence rate of kidney stones, there is no effective drug prevention and treatme...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P13/04A23L1/09
Inventor 张朝燕吴文惠王春晓
Owner SHANGHAI OCEAN UNIV
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