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Method for preparing medicinal composition for perianal anaesthetic analgesia of postoperation

A composition and drug technology, applied in the direction of drug combination, anesthetic, pharmaceutical formula, etc., can solve the problems of small side effects, lack of reliable curative effect, restricting the promotion of anal diseases, etc., and achieve the effect of good absorption and definite curative effect

Inactive Publication Date: 2012-07-11
张伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] For a long time, the continuous and severe pain after anal disease surgery has seriously affected the postoperative rehabilitation and quality of life of patients, and restricted the promotion of surgical treatment of anal diseases
In order to effectively treat the postoperative pain of anal diseases, many experts and scholars have made various attempts on postoperative analgesia for anal diseases, but there is still no long-acting narcotic analgesic with reliable curative effect and small side effects in clinical practice.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1, raw material drug weight ratio: 4 parts of procaine; 6 parts of eugenol; 15 parts of peach gum; 2 parts of borneol; 15 parts of litsea cubeba oil; share. It can be prepared according to the following method: take the above-mentioned peach gum and add it to equal volume of water, add arrow pine grass alkali through a 200-mesh sieve, keep stirring for 30 minutes at 40 ° C, cool down to room temperature, add litsea cubeba oil, cloves Phenol and methyl eugenol, continue to stir for 15 minutes, add procaine and borneol passed through a 200-mesh sieve, continue to stir for 15 minutes, and then pack.

Embodiment 2

[0013] Embodiment 2, raw material drug weight ratio: 6 parts of procaine; 4 parts of eugenol; 15 parts of peach gum; 3 parts of borneol; 15 parts of litsea cubeba oil; share. It can be prepared according to the following method: take the above-mentioned peach gum and add it to equal volume of water, add arrow pine grass alkali through a 200-mesh sieve, keep stirring for 30 minutes at 60 ° C, cool down to room temperature, add litsea cubeba oil, cloves Phenol and methyl eugenol, continue to stir for 15 minutes, add procaine and borneol passed through a 200-mesh sieve, continue to stir for 15 minutes, and then pack.

Embodiment 3

[0014] Embodiment 3, raw material drug weight ratio: 5 parts of procaine; 5 parts of eugenol; 15 parts of peach gum; 3 parts of borneol; 15 parts of litsea cubeba oil; share. It can be prepared according to the following method: take the above-mentioned peach gum and add it to equal volume of water, add arrow pine grass alkali through a 200-mesh sieve, keep stirring for 30 minutes at 50 ° C, cool down to room temperature, add litsea cubeba oil, cloves Phenol and methyl eugenol, continue to stir for 15 minutes, add procaine and borneol passed through a 200-mesh sieve, continue to stir for 15 minutes, and then pack.

[0015] The effective combination of medicines prepared by the method of the invention is coordinated with each other, and is used for anesthesia and analgesia after perianal surgery, has good absorption, definite curative effect, and simultaneously has lubricating and antibacterial effects. The above results are fully proved by the clinical data, and the relevant ...

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PUM

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Abstract

The invention discloses a method for preparing a medicinal composition for the perianal anaesthetic analgesia of postoperation. The medicinal composition comprises the following raw materials: procaine, eugenol, peach gum, borneol, litsea cubeba oil, thalicimine and methyl eugenol, and is characterized in that: the method for preparing the medicinal composition comprises the following steps of: adding the peach gum into isopyknic water, adding the thalicimine which is sieved with a 200-mesh sieve, and stirring continuously for 30 minutes; adding the litsea cubeba oil, eugenol and the methyl eugenol at room temperature, and continuing to stir for 15 minutes; and adding the procaine and the borneol which is sieved with the 200-mesh sieve, continuing to stir for 15 minutes and packaging intoseparated bags. Clinical experiments prove that the medicinal composition for treating the perianal anaesthetic analgesia of the postoperation has the characteristics of high absorption, definite curative effect, high safety, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a pharmaceutical composition for anesthesia and analgesia after perianal surgery. Background technique [0002] For a long time, the continuous and severe pain after anal disease surgery has seriously affected the postoperative rehabilitation and quality of life of patients, and restricted the promotion of surgical treatment of anal diseases. In order to effectively treat the postoperative pain of anal diseases, many experts and scholars have made various attempts on postoperative analgesia for anal diseases, but there is still a lack of long-acting narcotic analgesics with reliable curative effect and small side effects in clinical practice. Contents of the invention [0003] The technical task of the present invention is to provide a method for preparing an analgesic and analgesic pharmaceutical composition after perianal surgery with a cert...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61P23/02A61P29/00A61P31/04A61K31/245A61K31/045A61K31/085A61K31/473
Inventor 张伟刘艳郝伟英
Owner 张伟
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