Preparation methods of Chuanxiongchatiao granule extracts and preparations thereof

Abstract

The invention relates to preparation methods of Chuanxiongchatiao granule extracts and preparations thereof. Specifically, the preparation method of the preparations comprises the following steps: (1) taking the rhizome of chuanxiong, radix angelicae, angelica polyclada, asarum, divaricate saposhnikovia root and liquorice, adding water to decoct the medicines, filtering the decoction and keeping the soup for later use; (2) extracting volatile oils from mint and schizonepeta for later use, filtering the water solution of the volatile oils and merging the filtrate with the soup obtained in the step (1); (3) carrying out nanofiltration on the merged soup obtained in the step (2) with a film, abandoning the dialyzate and spray drying the obtained concentrates to prepare extract powder as the extracts of the preparations; and (4) uniformly doping the volatile oils obtained in the step (2) in the extract powder obtained in the step (3) and then optionally doping pharmaceutically acceptable auxiliary materials uniformly to prepare the preparations. The invention also relates to the extracts and preparations obtained by the methods. The methods have the characteristics of low cost, low possibility of damage of thermosensitive ingredients and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a preparation method of Chuanxiong tea preparation, especially Chuanxiong tea-tiao granules, in particular to the process of obtaining the extract after extracting medicinal materials in the preparation process of Chuanxiong tea preparation, and further preparing the preparation method. Background technique [0002] The original prescription of Chuanxiong Chatiao Granules comes from the "Taiping Huimin Heji Bureau Prescription" of the Song Dynasty. It has the effect of dispelling wind and relieving pain. It is used for headache due to wind pathogens, or aversion to cold, fever, and nasal congestion. This prescription is mainly composed of Chuanxiong, Nepeta, Fangfeng, Asarum, Angelica, notopterygium, mint, and licorice (see, Lin Xiaolan. Analysis of the clinical application of Chuanxiong Chatiao Granules [J]. Beijing Traditional Chinese Medicine, 2004, 23(3): 1...

AI Technical Summary

Problems solved by technology

[0005] In the existing process described above, after the water extracts of the six medicinal materials are mixed with the remaining water extracts of the volatile oil extraction in step (2), a concentration section is required. Because the concentration of the feed liquid is low, the evaporation process requires a large amount of water. Energy consumption, and in the process of evaporation and concentration, the product will be damaged to a certain extent if the temperature is too high

In particular, the existing process has problems such as high concentration temperature, long concentration time, loss of active ingredients and volatile components, difficulty in achieving high relative density quality requirements in one-step concentration, easy fouling of equipment, and waste liquid discharge.

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