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Coptis and radix sophorae flavescentis anti-dysenteric particle as well as preparation method and application of coptis and radix sophorae flavescentis anti-dysenteric particle

A technology for relieving dysentery and granules, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, bulk delivery, etc., which can solve the problem of no obvious improvement in curative effect, strict restrictions on the withdrawal period, and aggravation of drug resistance of pathogenic bacteria and other problems, to achieve the effect of definite curative effect, low production cost, and treatment of bacillary dysentery

Inactive Publication Date: 2012-10-10
SICHUAN JINRUIKE ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the process of using these medicines, there are two major problems: first, due to the non-standard and long-term medication of livestock and poultry, livestock and poultry have produced obvious drug resistance. No obvious increase or even continuous decline; second, in the actual application of this type of drug, due to the inability to strictly limit the withdrawal period and the overdose of the drug, the accumulation of the drug in the animal body continues to increase, resulting in In food, drug residues seriously exceed the standard
Digestive system diseases are the most harmful diseases to livestock and poultry. The use of a large number of antibiotics not only aggravates the drug resistance of pathogenic bacteria, but also increases the drug residues in animal products, which ultimately affects the health of consumers.

Method used

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  • Coptis and radix sophorae flavescentis anti-dysenteric particle as well as preparation method and application of coptis and radix sophorae flavescentis anti-dysenteric particle
  • Coptis and radix sophorae flavescentis anti-dysenteric particle as well as preparation method and application of coptis and radix sophorae flavescentis anti-dysenteric particle
  • Coptis and radix sophorae flavescentis anti-dysenteric particle as well as preparation method and application of coptis and radix sophorae flavescentis anti-dysenteric particle

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Weigh 400g of coptis, 90g of sophora, 300g of pulsatilla, 90g of myrobalan, and 120g of licorice. Crush Coptidis Rhizoma into Coptidis Rhizoma Powder, and pass through a 100-mesh sieve. Take the remaining four medicinal materials, add 1.5 times the total mass of the four medicinal materials and soak them in water for 0.3h, then add 6 times the total mass of the four medicinal materials and decoct them for 2 hours, filter to obtain the first filtrate and the first filter residue Add four kinds of medicinal materials total mass 4 times water decoction 2h again in the filter residue for the first time, filter, get the filtrate and filter residue for the second time; Add four kinds of medicinal materials total mass 4 in the filter residue for the second time again Double the amount of water to decoct for 2 hours, filter to obtain the third filtrate. The first, second and third filtrates were combined and concentrated to form a thick paste with a relative density of 1.3 at ...

Embodiment 2

[0030] Weigh 400g of coptis, 90g of sophora, 300g of pulsatilla, 90g of myrobalan, and 120g of licorice. Crush Coptidis Rhizoma into Coptidis Rhizoma Powder, and pass through a 100-mesh sieve. Take the remaining four kinds of medicinal materials, add water twice the total mass of the four medicinal materials and soak for 0.5h, then add water 4 times the total mass of the four medicinal materials and decoct for 1.5h, filter to obtain the first filtrate and the first time filter residue; add four kinds of medicinal materials total mass 3 times of water decocting 1.5h in the filter residue for the first time again, filter, get the second filtrate and the second filter residue; add four kinds of medicinal materials total mass again in the second filter residue Water with 3 times the mass was decocted for 1.5h, filtered to obtain the third filtrate. The first, second and third filtrates were combined and concentrated to form a thick paste with a relative density of 1.3 at 80°C. A...

Embodiment 3

[0032]Weigh 400g of coptis, 90g of sophora, 300g of pulsatilla, 90g of myrobalan, and 120g of licorice. Crush Coptidis Rhizoma into Coptidis Rhizoma Powder, and pass through a 100-mesh sieve. Take the remaining four medicinal materials, add water twice the total mass of the four medicinal materials and soak for 2 hours, then add water three times the total mass of the four medicinal materials and decoct for 1 hour, filter to obtain the first filtrate and the first filter residue; Add four kinds of medicinal materials total mass 3 times water decocting 1.5h again in the filter residue for the first time, filter, get the filtrate and the second filter residue for the second time; Add four kinds of medicinal materials total mass 3 times in the second filter residue Double the water and decoct for 1.5h, filter to get the third filtrate. The first, second and third filtrates were combined and concentrated to form a thick paste with a relative density of 1.3 at 80°C. Add crushed C...

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Abstract

The invention discloses a coptis and radix sophorae flavescentis anti-dysenteric particle as well as a preparation method and an application of the coptis and radix sophorae flavescentis anti-dysenteric particle and aims at solving the problems that livestock and poultry can generate medicine resistance on the exiting medicine, and meanwhile, the medicine residue can be caused. The particle is prepared from the following ingredients in parts by weight: 400 parts of coptis, 90 parts of radix sophorae flavescentis, 300 parts of Chinese pulsatilla root, 90 parts of myrobalan and 120 parts of liquorice. The recipe of the coptis and radix sophorae flavescentis anti-dysenteric particle is reasonable, the raw medical material resources are wide, the prepared products are mainly used for treating livestock and poultry dampness-heat of liver and gallbladder, heart and stomach fire, damp and hot dysentery, lingering dysentery, piglet white scour and yellow scour, and has the effects of clearing away heat to moisten dryness, purging fire to remove toxin and relieving diarrhea with astringents. Clinic tests prove that the curative effect is exact. The production process selected by in the preparation method provided by the invention has a short production period, the production cost is low, the operation is easy, in addition, active ingredients of raw medical materials are extracted to the furthest degree, and the curative effect of the produced products is stable. Meanwhile, the preparation selected for the coptis and radix sophorae flavescentis anti-dysenteric particle can adapt to the market requirements and the medication habits, and the transportation and the storage are also very convenient.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to Lian Shen Zhi Li granule, its preparation method and application. Background technique [0002] Sichuan is a large province of animal husbandry, its pig industry ranks first in the country, and its poultry industry is also booming. In 2003, Sichuan raised 197 million livestock and 1.41 billion poultry, and with the vigorous development of animal husbandry, it showed an upward trend year by year. By the end of 2005, the number of livestock and poultry had reached 212.4 million and 1.68 billion. . However, due to the ubiquity of some common diseases, such as Escherichia coli and Salmonella pullorum, among livestock and poultry, the development of the livestock and poultry industry is seriously restricted. Salmonella pullorum can cause disease in chicks, lower egg production rate of laying hens, and even lead to higher mortality. In the census of animal epidemics in Sichuan Pro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/16A61P31/04
Inventor 姜南卢亚艺姜均
Owner SICHUAN JINRUIKE ANIMAL PHARMA