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Production process of traditional Chinese medicine for treating anhypnia

A production process and a technology for insomnia, which are applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, and can solve the problems of inability to effectively extract the active ingredients of jujube seed

Inactive Publication Date: 2012-10-24
贵州大隆药业有限责任公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention: Aiming at the defects that the existing technology cannot effectively extract the medicinal components of Ziziphus jujube Seed, Radix Paeoniae Alba, Bupleurum and Albizia Julibrissin, a A process that can not only improve the extraction rate of saponins, but also effectively extract flavonoids

Method used

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  • Production process of traditional Chinese medicine for treating anhypnia
  • Production process of traditional Chinese medicine for treating anhypnia

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Embodiment Construction

[0019] Concrete embodiments of the present invention are as follows:

[0020] First, weigh 650g of Suanzaoren, 380g of Bupleurum, 380g of Radix Paeoniae Alba and 480g of Albizia Julibrissin, add 10 times the amount of ethanol with a concentration of 50-90% of the medicinal materials, and the concentration of 70% ethanol is the best, and reflux for 2 hours , filtered to obtain filtrate 1, the medicinal residues were refluxed for 2 hours with 70% ethanol of 8 times the amount of medicinal materials, filtered to obtain filtrate 2, and the filtrates obtained twice were combined;

[0021] Second, decoct the dregs with 8 times the amount of medicinal materials for 2 hours to obtain decoction 1; add 8 times the amount of medicinal materials to decoct the dregs for 2 hours to obtain decoction 2, and combine decoction 1 and decoction 2. Stand still for 8 hours, and filter to obtain the filtrate;

[0022] Third, combine the filtrates extracted with two different s...

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Abstract

The invention discloses a production process of the traditional Chinese medicine for treating anhypnia. The production process includes the following steps: 1 weighing spina date seeds, radix paeoniae alba, radix bupleuri and albizia julibrissin, adding ethanol, extracting for 1-4 times through reflux, and combining the filtrate; 2 adding water into the obtained dreg, decocting for 1-4 times, combining the decocted medicine solution, standing, and filtering to obtain filtrate; 3 combining the two kinds of obtained filtrate, concentrating, and drying in vacuum or spray mode; 4 adding water into other four medicines, decocting for 2-4 times, wherein each time lasts for 1-3 hours, combining and decocting the obtained medicine solution, standing, filtering, concentrating the filtrate, and drying in vacuum or spray mode; and 5 performing palletizing on the two obtained powder, drying the powder granules, smashing, sieving, adding magnesium stearate, starch and superfine silica powder, and filling the powder in capsules to obtain the traditional Chinese medicine for treating anhypnia. By means of the technical scheme of the production process, effective part flavonoid can be effectively extracted, simultaneously the extraction rate of the effective part saponins is improved, and accordingly, the curing effect of the 'shumian capsule' is remarkably improved.

Description

technical field [0001] The invention relates to a production process of a medicine, in particular to a production process of a medicine for treating insomnia. Background technique [0002] Suanzaoren: It is the dry and mature seed of the Rhamnaceae plant Suanzaoren, which has the functions of nourishing the liver, calming the heart, and promoting body fluid. Its saponins and flavonoids are its main active ingredients. In the quality standard of Shumian Capsules, the jujube kernel is a thin layer to identify jujuboside a, so the clear spots of jujuboside a are used as the inspection index. [0003] Paeoniae Alba: It is the dry root of Paeoniae officinalis, which has the functions of calming the liver and relieving pain, nourishing blood and regulating menstruation. Total glucosides of paeony is the main active ingredient in Radix Paeoniae Alba. The quality standard of Shumian Capsules is based on the determination of paeoniflorin content, so paeoniflorin is used as the inve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P25/20A61K35/64
Inventor 刘念宁牛伟王世辉
Owner 贵州大隆药业有限责任公司
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