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External use health care product for reducing intraocular pressure of diabetes mellitus eye diseases

A technology for diabetic eye disease and health care products, applied in the field of health care products, can solve problems such as unsatisfactory recovery and elevated intraocular pressure, and achieve the effects of reducing systemic side effects and reducing absorbed doses

Inactive Publication Date: 2012-10-31
WUJIANG YISHENG TEXTILE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

40% of people with type 2 diabetes have already developed diabetic retinopathy when they are diagnosed, and 20 years after the diagnosis of diabetes, all people with type 1 diabetes and 60% of people with type 2 diabetes will develop different degrees of diabetic retinopathy. Currently There is no good medicine for diabetic retinopathy, and surgery is generally used for treatment. However, the recovery after surgery is often unsatisfactory, and 80% of patients undergoing surgery will experience a sharp increase in intraocular pressure. , patients have symptoms of nausea, dizziness, vomiting, bleeding, and even surgery failures, so it is very valuable to develop health products that reduce intraocular pressure in diabetic eye diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The present invention relates to a kind of external health product for reducing intraocular pressure of diabetic eye disease, it is characterized in that:

[0012] Take 2 mg of Lycium barbarum polysaccharide, 3 mg of Alisma polysaccharide, 4 mg of total saponins of saffron, 4 mg of total saponins of ginseng, 15 mg of total saponins of gardenia, 3 mg of mannitol, 15 mg of tyloxapol, and 15 mg of disodium edetate. mg, potassium chloride 15 mg, azone 25 mg, add 1000 mg of pure water, dissolve, filter, add 2 ml of hydrochloric acid to adjust the pH to 7.0.

Embodiment 2

[0014] Take wolfberry polysaccharide 5 mg, Alisma polysaccharide 7 mg, saffron total saponins 7 mg, ginseng total saponins 7 mg, gardenia total saponins 45 mg, mannitol 7 mg, tyloxapol 25 mg, edetate disodium 25 mg mg, potassium chloride 25 mg, azone 25 mg, add 3000 mg of pure water, dissolve, filter, add 3 mg of potassium bicarbonate to adjust the pH value to 7.0.

Embodiment 3

[0016] Its dosage is to drop 3 drops of the external health care product for reducing the intraocular pressure of diabetic ophthalmopathy of the present invention to the temple, three times a day for 10 consecutive days.

[0017] Case selection: 30 patients with recurrent diabetic eyes with decreased vision, sometimes eye pain, paroxysmal iris, dilated pupils, a total of 54 eyes with intraocular pressure exceeding 22mmHg, some patients with optic atrophy, and blindness for no more than 2 months.

[0018] 10 days after the treatment, the average intraocular pressure of 54 animals decreased significantly from (9.2±0.1) to (17.2±0.4),

[0019] The average intraocular pressure of 34 eyes ranged from (9.2±0.1) to (12.1±0.5),

[0020] The average intraocular pressure of 20 mice ranged from (12.1±0.5) to (17.2±0.4),

[0021] Eye pain disappeared in all patients, rainbow vision disappeared, and pupils became smaller

[0022] Changes in intraocular pressure age diabet...

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PUM

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Abstract

The invention relates to an external use health care product for reducing intraocular pressure of diabetes mellitus eye diseases. The external use health care product is characterized by comprising 2-5 milligram of lycium barbarum polysaccharide, 3-7 milligram of rhizoma alismatis polysaccharide, 4-7 milligram of stigma croci total saponins, 4-7 milligram of ginseng total saponins, 15-45 milligram of jasmine total saponins, 3-7 milligram of mannitol, 15-25 milligram of tyloxapol, 15-25 milligram of edetate disodium, 15-25 milligram of potassium chloride, 25-25 milligram of azone, 2-5 milligram of hydrochloric acid or 1-3 milligram of potassium hydroxide (the pH value is adjusted) and 1000-3000 milligram of pure water. The external use health care product can clear liver, improve vision, scatter the liver, purge intense heat, contract pupils, stop pain and lower the intraocular pressure.

Description

technical field [0001] The invention relates to the field of health products, in particular to an external health product for reducing intraocular pressure of diabetic eye disease. Background technique [0002] According to a domestic eye disease epidemiological survey, diabetic eye disease has become a major eye disease in my country. One of the threats of diabetes is microvascular and macrovascular complications caused by long-term poor blood sugar control, which can make patients blind. 40% of people with type 2 diabetes have already developed diabetic retinopathy when they are diagnosed, and 20 years after the diagnosis of diabetes, all people with type 1 diabetes and 60% of people with type 2 diabetes will develop different degrees of diabetic retinopathy. Currently There is no good medicine for diabetic retinopathy, and surgery is generally used for treatment. However, the recovery after surgery is often unsatisfactory, and 80% of patients undergoing surgery will exper...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P27/02A61K31/715
Inventor 李国
Owner WUJIANG YISHENG TEXTILE
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