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Traditional Chinese medicine compound preparation for preventing and treating vaginitis and preparation method thereof

A compound preparation and vaginitis technology are applied in the field of traditional Chinese medicine extract compound gel preparation and preparation thereof, and can solve the problems of repeated inflammation, liver damage, large toxic and side effects, etc., and achieve high bioavailability, uniform drug distribution, and drug good stability

Inactive Publication Date: 2014-03-12
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, local and systemic antibiotics and azole antifungal drugs are mostly used in the clinical treatment of vaginitis. The curative effect is positive, but vaginitis is very easy to relapse. Patients with recurrent vaginitis need to take antifungal drugs for a long time, which is easy to damage the liver. At the same time, other side effects are also obvious, such as gastrointestinal discomfort, headache and flushing. Pregnant women are one of the people who are prone to vaginitis. The possibility of increasing the incidence of teratogenesis and stillbirth cannot be ruled out by the application of antifungal drugs. Therefore, antifungal drugs Most of them are not accepted by patients with vaginitis during pregnancy. At the same time, simply using traditional Chinese medicine or western medicine for antibacterial, sterilizing, and anti-inflammation has a lot of side effects and poor long-term effect. It is very easy to kill the beneficial bacteria in the vagina while anti-inflammatory and sterilizing. , destroy the normal flora balance in the vagina, lead to other vaginal diseases, or lead to repeated attacks of inflammation, the treatment and recovery time will be longer
Most of the medicines for vaginitis on the market are in the form of direct sterilization and anti-inflammation, and the effect of preventing and treating vaginitis is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: a kind of traditional Chinese medicine compound preparation of prevention and treatment of vaginitis, is made up of the main raw material of following weight parts:

[0028] 70 parts of Lactobacillus metabolites, 28 parts of Sophora flavescens, 10 parts of Cortex Phellodendri, 10 parts of Fructus Cnidii, 10 parts of peppermint, 30 parts of Carbopol 940, 60g of glycerin, 15g of peppermint oil, 3g of chitosan, 5 parts of sodium hydroxide.

[0029] A preparation method of a traditional Chinese medicine compound preparation for preventing and treating vaginitis: take the above-mentioned proportioning raw materials, take Chinese medicine extracts Sophora flavescens, Cortex Phellodendri, Fructus Cnidii and Peppermint, and mix them uniformly to obtain Chinese medicine fine powder for later use; Lactobacillus metabolites, shell The polysaccharide is combined with the fine powder of traditional Chinese medicine, and purified water is added to dissolve it into a raw ...

Embodiment 2

[0030] Embodiment 2: a kind of traditional Chinese medicine compound preparation for preventing and treating vaginitis is made up of the following main raw materials in parts by weight:

[0031] 20 parts of Lactobacillus metabolites, 15 parts of Sophora flavescens, 20 parts of Cortex Phellodendron, 20 parts of Cnidium mongolicum, 5 parts of peppermint, 5 parts of Carbopol 940, 40 parts of glycerin, 30 parts of peppermint oil, 8 parts of chitosan, sodium hydroxide 2 servings.

[0032] A preparation method of a traditional Chinese medicine compound preparation for preventing and treating vaginitis: take the above-mentioned proportioning raw materials, take Chinese medicine extracts Sophora flavescens, Cortex Phellodendri, Fructus Cnidii and Peppermint, and mix them uniformly to obtain Chinese medicine fine powder for later use; Lactobacillus metabolites, chitosan The sugar is combined with the fine powder of traditional Chinese medicine, mixed evenly, and purified water is added...

Embodiment 3

[0033] Embodiment 3: a kind of traditional Chinese medicine compound preparation of preventing and treating vaginitis is made up of the following main raw materials in parts by weight: 60 parts of Lactobacillus metabolites, 22 parts of Sophora flavescens, 15 parts of Cortex Phellodendri, 15 parts of Fructus Cnidii, 8 parts of Peppermint, Carbopol 20 parts of Pu 940, 50 parts of glycerin, 20 parts of peppermint oil, 5 parts of chitosan, 4 parts of sodium hydroxide.

[0034]A preparation method of a traditional Chinese medicine compound preparation for preventing and treating vaginitis: take the above proportioning raw materials, mix carbopol 940 and chitosan, add purified water, stir well, add glycerin and peppermint oil, mix well, make it swell naturally, As the gel matrix solution I, for later use; take Chinese medicine extracts Sophora flavescens, Cortex Phellodendri, Fructus Cnidii, Peppermint, and lactobacillus metabolites, mix well and add purified water to make a raw mate...

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PUM

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Abstract

The invention provides a traditional Chinese medicine compound preparation for preventing and treating vaginitis and a preparation method thereof. The traditional Chinese medicine compound preparation comprises the following main raw materials in parts by weight: 50-70 parts of biological peptide, 15-28 parts of kuh-seng, 10-20 parts of cortex phellodendri, 10-20 parts of fructus cnidii, 5-10 parts of mint, 3-8 parts of chitosan, 5-30 parts of carbopol 940, 40-60 parts of glycerol, 2-5 parts of sodium hydroxide and 15-30 parts of mint oil. The biological peptide and traditional Chinese medicines are mixed and complementary mutually, can adjust balance, inhibit bacteria, purge fire for removing toxin, sterilize, resist inflammations, clear heat, dry dampness, dispel the wind, and kill parasites. Compared with the available preparation for preventing and treating the vaginitis, the traditional Chinese medicine compound preparation adopts a principle of mainly adjusting the balance, sterilizing and resisting the inflammations, and auxiliarily purging the fire for removing the toxin, clearing the heat, drying the dampness, dispelling the wind and killing the parasites, and is used for improving an acid environment in a vagina, inhibiting and eliminating the growth of the harmful bacteria, detoxifying, eliminating the dampness and diminishing the inflammations, so that the purpose of preventing and treating the vaginitis is achieved; and the preparation method is stable, practicable, controllable and applicable to mass production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract compound gel preparation and a preparation method thereof, in particular to a traditional Chinese medicine compound gel preparation for preventing and treating vaginitis and a preparation method thereof. Background technique [0002] Vaginitis is an inflammation of the vaginal mucosa and submucosal connective tissue, and is a common disease in gynecological clinics. Clinically, vaginitis is characterized by changes in the characteristics of leucorrhea and vulvar itching and burning pain. Pain during sexual intercourse is also common. When the infection involves the urethra, there may be symptoms such as dysuria and urgency. Vaginitis has a slow onset and strong recurrence , difficult to thoroughly treat the characteristics. From childhood to old age, women all over the world suffer from almost 100% chance of suffering from vaginitis. Young girls and postmenopausal women suffer from estro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/02A61K36/756A61P15/02A61P31/04A61K35/74A61K35/747
Inventor 王虹顾建勇
Owner TAISHAN MEDICAL UNIV
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