N(2)-L-alanyl-L-glutamine/compound amino acid injection (18AA-V) pharmaceutical composite preparation

Abstract

The invention relates to the technical field of medicines and discloses an N(2)-L-alanyl-L-glutamine / compound amino acid injection (18AA-V) pharmaceutical composite preparation which is prepared by mixing N(2)-L-alanyl-L-glutamine and compound amino acid injection (18AA-V). The pharmaceutical composite preparation has the advantages of definite components, stable quality, high bioavailability, less adverse reactions and the like and has a good application prospect in clinical practice.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to an N(2)-L-alanyl-L-glutamine / compound amino acid injection (18AA-V) drug combination preparation. Background technique [0002] N(2)-L-alanyl-L-glutamine is a component of parenteral nutrition, which can promote positive nitrogen balance, regulate muscle protein synthesis, and prevent intestinal mucosal passage caused by long-term parenteral nutrition. Increased permeability and atrophy, C can enhance immune function and prevent the occurrence of bacteremia. N(2)-L-alanyl-L-glutamine can be decomposed into alanine and glutamine in the body, and glutamine can be supplemented by parenteral nutrition infusion. [0003] Since N(2)-L-alanyl-L-glutamine has the function of promoting positive nitrogen balance, and its solution is a hypertonic solution, the maximum concentration of the infusion solution should not exceed 3.5%. , there will be serious adverse reactions such as nitrogen...

AI Technical Summary

Problems solved by technology

[0003] Since N(2)-L-alanyl-L-glutamine has the function of promoting positive nitrogen balance, and its solution is a hypertonic solution, the maximum concentration of the infusion solution should not exceed 3.5%. , there will be serious adverse reactions such as nitrogen loss, vascular stimulation and dehydration of vital organs, which will cause N(2)-L-alanyl-L-glutamine to fail to meet clinical requirements

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