Compound avermectin suspension for expelling and treating parasites in livestock and preparation method thereof

A compound avermectin and endoparasite technology, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, liquid delivery, etc., to achieve the effects of simple production process, stable product quality and low irritation

Inactive Publication Date: 2013-05-08
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are no reports and sales of compound abamectin suspension for livestock at home and abroad

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0010] The suspension system uses Avermectin , Praziquantel plus appropriate amount of suspending agent, wetting agent, pH regulator and other shearing. During actual production, the main drug abamectin 0.1g, praziquantel 2.5g, carbomer 0.1g, sodium lauryl sulfate 0.1g, citric acid 0.1g, sucrose 110g, water 87.1g are desirable. In the preparation process, carbomer and sucrose are added with water to make a glue solution, which is put into an emulsifier and then added with citric acid, sodium lauryl sulfate, abamectin and praziquantel to make it by shearing. Before the preparation, the raw and auxiliary materials need to be crushed through a 60-100 mesh sieve. During the preparation process, due to the shearing effect, the raw and auxiliary materials are all made into extremely fine particles, which are evenly dispersed in the suspension.

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PUM

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Abstract

The invention relates to a compound avermectin suspension for expelling and treating parasites in livestock and a preparation method thereof. The suspension mainly overcomes the defects of complex production process, inconvenient administration, inaccurate dose, poor parasite expelling effect and the like in existing parasite expelling preparations. The suspension is mainly composed of: avermectin, praziquantel, Carbomer, citric acid, lauryl sodium sulfate, water, and a flavoring agent. The preparation method consists of: adding water into the Carbomer to make a glue solution, placing the glue solution into an emulsifying machine, then adding the citric acid, the lauryl sodium sulfate, the avermectin, the praziquantel, and the flavoring agent, and performing shearing, thus obtaining the suspension. The drug provided in the invention has the advantages of simple production process, stable quality, simple administration operation, accurate dose, and substantial parasite expelling effect.

Description

technical field [0001] The invention relates to a compound abamectin suspension for expelling and treating internal parasites in livestock and a preparation method thereof. Background technique [0002] There are many kinds of parasitic diseases and they are widely distributed. They are very common and serious diseases of livestock. They seriously affect the production of meat, milk and eggs, the quality of fur and the working ability of draft animals. Some zoonotic parasitic diseases also directly harm human health. Therefore, parasitic diseases not only hinder the development of animal husbandry and cause huge economic losses, but also are the most common and serious public health problems. In the past 10 years, due to insufficient investment in science and technology and funds, there are not many new technologies suitable for production, and there are basically no major breakthroughs and innovations in parasitic disease control technology. Chemical control is still the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K9/10A61P33/14A61P33/10A61K31/4985
Inventor 刘元元郝智慧王艳玲
Owner QINGDAO VLAND BIOTECH INC
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