System and a method of directly optimizing static-state intensity-modulated sub-field shapes and machine hop count thereof

A machine-jumping and sub-field technology, applied in radiation therapy, treatment, etc., can solve problems such as low utilization rate of radiation, affecting the accuracy of patient exposure dose, increasing irradiation time, etc., achieving fast optimization speed and improving implementability Good performance, speed and effect

Inactive Publication Date: 2013-05-08
合肥克瑞斯信息科技有限公司
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Problems solved by technology

Long-term clinical application shows that the defects of the "two-step method" can be summarized as follows: (1) The number of subfields in each irradiation field is large, and the total number of irradiation jumps (MU) is often the number of conventional/conformal irradiation fields; times, this situation will not only increase the irradiation time, but also increase the probability of leakage, head scattering and tongue-groove effects; (2) some small, irregu

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  • System and a method of directly optimizing static-state intensity-modulated sub-field shapes and machine hop count thereof
  • System and a method of directly optimizing static-state intensity-modulated sub-field shapes and machine hop count thereof
  • System and a method of directly optimizing static-state intensity-modulated sub-field shapes and machine hop count thereof

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Embodiment Construction

[0033] Such as figure 2 As shown, the present invention directly optimizes the static intensity modulated sub-field shape and its method of machine hops, and the specific implementation is as follows:

[0034] (1) According to the Dicom-RT format, import CT image data, target area and region of interest definition information, and field direction information, and expand outward to a certain size according to the projection of the target area in the field direction as the corresponding field direction. Field shape, according to the CT image data target area and the definition information of the region of interest, the calculation point is sampled to obtain the calculation point information of each area;

[0035] For example, for the rhinitis test model, import 57 pieces of CT image data and the regions of interest (left and right eyes, spinal cord, brainstem, and left and right parotid glands) and target area information (GTV, PTV) and field direction information corresponding...

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Abstract

The invention discloses a system and a method of directly optimizing static-state intensity-modulated sub-field shapes and machine hop count thereof. The system comprises an input module, a data processing module, an optimizing module and an optimized result output module. According to requirements of radiotherapy plan constitutors, the system and the method automatically build corresponding objective functions, regulation of the sub-filed shapes is conducted through the genetic algorithm, optimization of sub-field weight is conducted through the conjugate gradient algorithm, the genetic algorithm and the conjugate gradient algorithm are alternated for optimization, and finally, the sub-filed shapes meeting requirements and the corresponding machine pop count weight of the sub-field shapes are obtained. By means of the method, each sub-filed shape in each radiation field direction, meeting the requirements, and the machine pop count of each sub-field shape can be rapidly obtained, and the optimized result is a sub-field array which can be directly implemented. The system and the method not only can effectively solves the precision problem existing in a traditional method, but also are simple to operate, and can improve plan drawing-up efficiency and plan implementation efficiency.

Description

technical field [0001] The invention relates to a system and method for minimizing the number of subfields and the total number of machine jumps corresponding to the multi-leaf grating when the multi-leaf grating is used for intensity modulation in precise radiotherapy. Background technique [0002] The general steps to obtain the implementable sub-field shape and the number of machine hops in static intensity-modulated radiotherapy are to first obtain the optimal intensity that satisfies the expected dose distribution in each direction by means of optimization algorithm optimization, and then perform sub-field segmentation on the optimized intensity , converted into subfields that can be implemented by MLC, this method is called "two-step method" for short. Since the intensity distribution optimization does not consider some constraints contained in the multi-leaf grating itself, these restrictions are only considered in the sub-field segmentation, so the sub-field segmenta...

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Application Information

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IPC IPC(8): A61N5/00
Inventor 曹瑞芬裴曦王捷吴宜灿
Owner 合肥克瑞斯信息科技有限公司
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