Skin antimicrobial gel recipe and preparation method thereof

Abstract

The invention discloses a skin antimicrobial gel recipe and a preparation method thereof. The gel comprises the raw materials of chitosan-iodine, glacial acetic acid, polysorbate-20, glycerin, potassium iodate, chitosan and purified water. The preparation method comprises the following steps of: (1) weighing; (2) adding the glacial acetic acid, the polysorbate-20, the glycerin and the purified water into the chitosan-iodine, mixing uniformly and dissolving completely; (3) dissolving the potassium iodate with the purified water, and adding the dissolved potassium iodate into the mixture to be stirred uniformly; (4) adding the chitosan to stir and dissolve; and (5) adding the purified water to 100% finally, slowly stirring to form the gel, standing and degassing to obtain a skin antimicrobial gel finished product. The skin antimicrobial gel has the advantages of no toxicity, no stimulus, good stability and no tolerance; and the skin antimicrobial gel is suitable for treating and preventing skin and subcutaneous infection and promoting wound healing, such as primary skin infection of impetigo vulgaris, furuncle and the like, secondary skin infection of eczema concurrent infection, trauma concurrent infection and the like as well as tinea manus and pedis, tinea corporis and tinea cruis which are caused by fungal infection.

Description

technical field [0001] The invention relates to a medical dressing, in particular to a chitosan iodine-containing dressing, in particular to a skin antibacterial gel. Background technique [0002] Iodine has been used for body disinfection for 150 years, but due to the low solubility of iodine in water, it is only 1.315×10 at 25°C. -3 mol / L, it cannot be used as an aqueous preparation; it is easy to sublimate at room temperature, and the content is unstable; it is irritating to the skin and mucous membranes, which limits its wide application. At present, most of the widely used iodine disinfectants are based on organic polymers or surface active substances, and through the network structure or micelles formed between the carrier molecules, iodine is "bound" in it by the conformational effect of electrons and space. , thereby changing the free state of iodine in general iodine preparations, enhancing its stability and bactericidal effect, and reducing irritation and yellow s...

AI Technical Summary

Problems solved by technology

At present, there is no patent application for making skin antibacterial gel with chitosan iodine