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Application for oleanolic acid saponin ingredient in preparation for anti-schistosome medicine
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The technology of oleanolic acid saponin and sugar oleanolic acid saponin is applied to the application field of oleanolic acid saponins in the preparation of anti-schistosomiasis drugs, and can solve the problem that the anti-schistosomiasis activity of Pulsatilla chinensis medicinal materials is not found.
Inactive Publication Date: 2013-07-03
JIANGXI HERBFINE HI TECH
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Problems solved by technology
After searching, no literature reports were found that Pulsatilla pulsatillae and its active components have anti-schistosomiasis activity
Method used
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[0036] According to the operation method of the conventional tablet, the above is mixed evenly, wet granulated, and finally magnesiumstearate is added, mixed evenly and compressed to form 500 mg per tablet.
[0037] The compound of the present invention is 3-O-α-L-rhamnopyranose-(1→2)[β-D-glucopyranose-(1→4)]-α-L-arabinopyranose olean acid saponins.
[0046] According to the operation method of conventional tablets, the above is mixed evenly, granulated by wet method, and filled into capsules, each 300mg.
[0047] The compound of the present invention is 3-O-α-L-rhamnopyranose-(1→2)[β-D-glucopyranose-(1→4)]-α-L-arabinopyranose olean acid saponins.
[0058] Proceed as usual for cataplasms, stir the above evenly, apply on the polyester anti-adhesive layer, dry at 60 degrees for 2 minutes, cover the polyurethane film backing layer, and slice it.
[0059] The compound of the present invention is 3-O-α-L-rhamnopyranose-(1→2)[β-D-glucopyranose-(1→4)]-α-L-arabinopyranose olean acid saponins.
[0060]
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Abstract
The invention relates to an application for oleanolic acidsaponin ingredient 3-O-alpha-L-rhamnpyranose-(1->2) [beta-D-glucopyranose-(1->4)]-alpha-L-arabinpyranose oleanolic acidsaponin in preparation for an anti-schistosome medicine. The dispersed state of the compound with the single ingredient may be liquid-state or solid-state in a preparation; and the medicine comprises various dosage forms of oral solution, capsules, paint, Babu plaster, spray agent, injection and the like.
Description
[0001] technical field [0002] The invention belongs to the technical field of medicine and veterinary medicine, and relates to an oleanolic acidsaponin component 3-O-α-L-rhamnopyranose-(1→2)[β-D-glucopyranose-(1→2) 4) Application of ]-α-L-arabinopyranose oleanolic acid saponin in the preparation of anti-schistosomiasis drugs, the composition has significant anti-schistosomiasis activity and can be used for the prevention and treatment of schistosomiasis in humans or other mammals. Background technique [0003] Pulsatilla medicinal material is taken from the dried root of Pulsatilla chinensis (Bunge) Regel, a plant of the genus Pulsatilla in the family Ranunculaceae, which is bitter in taste and cold in nature. Return stomach, large intestine meridian, tool heat-clearing and toxic substances removing, the merit of cooling blood and stopping dysentery. For pyretotoxic blood dysentery, pruritus vulvaeleukorrhagia, amoebic dysentery. According to literature reports, Pulsat...
Claims
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Application Information
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