Bleeding stopping sponge and preparation method thereof
A technology of hemostatic sponge and hemostatic material, which is applied in the field of hemostatic sponge and its preparation, can solve the problems of unstable preparations and low water absorption of modified starch, and achieve the effects of stable preparations, improved water absorption performance, and convenient preparation
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Embodiment 1
[0031] The hydroxypropyl distarch phosphate is etherified, cross-linked and esterified by chemical reagents such as propylene oxide and phosphoric acid to make a new modified starch, and then the modified starch slurry is placed in a microwave oven at 80 degrees 750W Heated for 3 minutes under the same conditions. After cooling, it was filtered with suction, washed with alcohol, dried, and freeze-dried at -45°C and a vacuum of 15 Pa for 15 hours to obtain the hemostatic sponge 1.
Embodiment 2
[0033] The hydroxypropyl distarch phosphate slurry was heated in a microwave oven at 80°C and 750W for 3 minutes. After cooling, filter with suction, wash with alcohol, dry, and then undergo etherification, cross-linking, and esterification with chemical reagents such as propylene oxide and phosphoric acid to make new modified starch. The hemostatic sponge 2 was obtained by freeze-drying under Pa for 15 hours.
Embodiment 3
[0035] The hydroxyethyl starch is subjected to etherification, crosslinking and esterification with chemical reagents such as propylene oxide and phosphoric acid to make a new modified starch, and then the modified starch slurry is heated in a microwave oven at 80 degrees and 750W. 3min. After cooling, it was suction filtered, washed with alcohol, dried, and freeze-dried at -45°C and a vacuum of 15 Pa for 15 hours to obtain a hemostatic sponge 3.
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