Bleeding stopping sponge and preparation method thereof

A technology of hemostatic sponge and hemostatic material, which is applied in the field of hemostatic sponge and its preparation, can solve the problems of unstable preparations and low water absorption of modified starch, and achieve the effects of stable preparations, improved water absorption performance, and convenient preparation

Inactive Publication Date: 2013-07-31
BEIJING JIADE SUNSHINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] An object of the present invention is to provide a new hemostatic sponge, which has good water absorption, safety, and st...

Method used

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  • Bleeding stopping sponge and preparation method thereof
  • Bleeding stopping sponge and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031] The hydroxypropyl distarch phosphate is etherified, cross-linked and esterified by chemical reagents such as propylene oxide and phosphoric acid to make a new modified starch, and then the modified starch slurry is placed in a microwave oven at 80 degrees 750W Heated for 3 minutes under the same conditions. After cooling, it was filtered with suction, washed with alcohol, dried, and freeze-dried at -45°C and a vacuum of 15 Pa for 15 hours to obtain the hemostatic sponge 1.

Embodiment 2

[0033] The hydroxypropyl distarch phosphate slurry was heated in a microwave oven at 80°C and 750W for 3 minutes. After cooling, filter with suction, wash with alcohol, dry, and then undergo etherification, cross-linking, and esterification with chemical reagents such as propylene oxide and phosphoric acid to make new modified starch. The hemostatic sponge 2 was obtained by freeze-drying under Pa for 15 hours.

Embodiment 3

[0035] The hydroxyethyl starch is subjected to etherification, crosslinking and esterification with chemical reagents such as propylene oxide and phosphoric acid to make a new modified starch, and then the modified starch slurry is heated in a microwave oven at 80 degrees and 750W. 3min. After cooling, it was suction filtered, washed with alcohol, dried, and freeze-dried at -45°C and a vacuum of 15 Pa for 15 hours to obtain a hemostatic sponge 3.

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Abstract

The invention relates to a bleeding stopping sponge and an application thereof. The bleeding stopping sponge is prepared through redenaturation of denaturated starch in the prior art, and microwave processing. The bleeding stopping sponge has the advantages of excellent water absorption effect, safety and stability, is biocompatible, and can be directly applied to bleeding wounds.

Description

technical field [0001] The invention relates to a hemostatic sponge and a preparation method thereof, in particular to a biocompatible hemostatic sponge which can be directly used on bloody wounds and a preparation method thereof. Background technique [0002] Bleeding is the most likely phenomenon in accidents and medical treatment. A large amount of bleeding will endanger human life. Therefore, it is necessary to stop bleeding in time for bleeding wounds. [0003] With the development of medicine, there are many kinds of hemostatic materials. In terms of biocompatibility, commonly used biocompatible hemostatic materials include: absorbable gelatin sponge, collagen sponge and other gelatin hemostatic materials; oxidized cellulose, oxidized regeneration Cellulose hemostatic materials; chitosan / chitin, starch polysaccharides and other natural biopolysaccharide hemostatic materials, etc. [0004] The content of the present invention relates to the hemostatic material of starc...

Claims

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Application Information

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IPC IPC(8): C08J9/28C08B31/00C08B31/16C08J3/24A61L15/28A61L31/04
Inventor 刘泊志
Owner BEIJING JIADE SUNSHINE TECH
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