Production process of capsaicin

A production process, capsaicin technology, applied in the production of bulk chemicals, natural dyes, azo dyes, etc., can solve the problems of high sales price and difficult processing technology

Inactive Publication Date: 2013-08-21
CHANGZHOU ADAM BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the international market, there is a certain gap in the supply of capsaicin, especially for high-purity capsaicin products used in the pharmaceutical field. The pro...

Method used

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  • Production process of capsaicin

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Effect test

Embodiment 1

[0034] (1) Raw material pretreatment

[0035] The peppers are vacuum-dried at low temperature (moisture content <22%), crushed (60 mesh), and set aside.

[0036] (2) Supercritical CO 2 extraction

[0037] 1. Tank washing operation of supercritical extraction device

[0038] The model of supercritical extraction device is HA120-50-01

[0039] ① First add 100ml~200ml of absolute ethanol to the extraction kettle.

[0040] ② Turn on the main power supply on the wall, turn on the main power supply of the equipment, and after the three-phase indicator light shows normal, turn on the power switch of the refrigeration and cold cycle to check whether it works normally.

[0041] ③ Before turning on the temperature control power of the extractor and separator, check whether the motor of the hot water tank can be rotated artificially, check the water level of the hot water tank, if the water level is insufficient, add water. Turn on the power switches of extraction Ⅰ, separation Ⅰ an...

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Abstract

The invention relates to a preparation method of an active ingredient in chili and particularly relates to a production process of capsaicin. According to the production process disclosed by the invention, a supercritical fluid extraction method is adopted for separating capsaicin and capsanthin, and a high performance liquid chromatography is further used for performing preparation on a crude extract to obtain high-purity nordi-hydrocapsaicin, capsaicin and dihydrocapsaicin. The production process disclosed by the invention has the advantages of quickness, high efficient and energy conservation and can be industrially popularized.

Description

technical field [0001] The invention relates to a preparation method of active ingredients in capsicum, in particular to a production process of capsaicin. Background technique [0002] Capsicum (Capicum) is the fruit of a Solanaceae Capsicum plant (Capicum frutescens L.). The main spicy substance. Natural capsaicin is composed of a series of homologues, mainly including capsaicin, dihydrocapsaicin, nordihydrocapsaicin, homodihydrocapsaicin, homocapsaicin etc., the content of these five components accounts for 99%, of which capsaicin and dihydrocapsaicin account for more than 90%, and nordihydrocapsaicin accounts for about 7%. [0003] Medical research and pharmacological clinical experiments have shown that capsaicin compounds are a kind of neurological drugs that do not produce drug dependence, and have analgesic, antipruritic, anti-inflammatory, antibacterial, and protective effects on cardiovascular and digestive systems; Its non-toxic, pungent and irritating characte...

Claims

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Application Information

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IPC IPC(8): C07C233/20C07C233/18C07C231/24C09B61/00
CPCY02P20/54
Inventor 叶亚东张娟全利朱文华胡娟肖慧李永忠潘鹂张俊杨紫俊马晓勋叶汝章
Owner CHANGZHOU ADAM BIOTECH
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