High-density distributed stereo electrode apparatus
A three-dimensional electrode, distributed technology, applied in the field of cell electroporation, can solve the problems of unsuitable high-throughput experimental operation, easy penetration of the three-dimensional electrode into tissue, low electroporation efficiency, etc., achieving low cost and making up for the electric field. The effect of unevenness and small electrode spacing
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Embodiment 1
[0026] see figure 1 , figure 2 , image 3 and Figure 4 The present invention provides a high-density distributed electrode device, including an electrode array 1 and an electrode fixing assembly, and the electrode array 1 is fixed on the electrode fixing assembly.
[0027] The electrode array 1 is composed of 37 solid cylindrical electrodes, and the arrangement rule is that all the electrodes are arranged in a regular hexagonal structure, and the distance between two adjacent electrodes is equal, and the distance between the two adjacent electrodes is equal. The spacing is the length of the sides, and the interior of the regular hexagon is divided into several small equilateral triangle units. An electrode is placed at the apex of each equilateral triangle, that is, all electrodes are divided into 3 groups of I, II, and III, and each equilateral triangle unit The vertices of belong to I, II, III respectively.
[0028] The inner diameter of the regular hexagon of the elec...
Embodiment 2
[0044] The present invention provides a high-density distributed electrode device. Other structures are the same as those in Embodiment 1. The arrangement rule of the electrode array is that all electrodes are arranged in a regular quadrilateral structure, and the distances between two adjacent electrodes are equal, so that The distance between two adjacent electrodes is the side length. Divide the interior of the regular quadrilateral into several small square units, and place an electrode at the vertex of each square, that is, all electrodes are divided into 4 groups of I, II, III, and IV. The vertices of the four square units belong to I, II, III, and IV respectively, and the electrodes of one group are used as positive electrodes, and the electrodes of the other groups are used as negative electrodes, and electric pulses are applied in turn.
Embodiment 3
[0046] The present invention provides a high-density distributed electrode device. Other structures are the same as those in Embodiment 1. The arrangement rule of the electrode array is that all electrodes are arranged in a regular hexagonal structure, and the distance between two adjacent electrodes is equal. , taking the distance between two adjacent electrodes as the side length, divide the plane into several small regular hexagonal units, and place an electrode at the vertex of each regular hexagonal unit, that is, all electrodes are divided into I, II, III, There are 6 groups of IV, V, and VI. The vertices of each regular hexagonal unit belong to I, II, III, IV, V, and VI respectively. The electrodes of one group are used as positive electrodes, and the electrodes of the remaining groups are used as negative electrodes. Electric pulses are applied in turn. .
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