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Natural medicine composition as well as preparation method and application for same

A technology of natural medicine and composition, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc.

Inactive Publication Date: 2013-09-18
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural medicine composition as well as preparation method and application for same

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Embodiment approach

[0031] (1) Preparation of psyllium radish seed decoction concentrated extract

[0032] According to the compatibility ratio of 1-4:1, take the seeds of plantain and radish, soak in distilled water for 1 hour, heat and decoct for 1 hour, filter with silk cloth, save the filtrate, add distilled water to the medicine dregs, soak, decoct, and filter in the same way. The secondary filtrates were mixed, concentrated by heating, filtered by an ultrafiltration membrane, and dried under reduced pressure to obtain the obtained product.

[0033] (2) Preparation of psyllium polysaccharide

[0034] Take plantago seed, extract with NaOH solution with pH of 9, filter the extract, adjust the filtrate to neutral with dilute hydrochloric acid, concentrate the solution, let it cool, add ethanol and leave it for 8 hours while stirring, filter off ethanol, anhydrous Soak in ethanol for 1 hour, and dry in an oven at 60°C.

[0035] (3) Preparation of radishin

[0036] Grind radish seeds, add exce...

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Abstract

The invention relates to a natural medicine composition as well as a preparation method and an application for the same. The natural medicine composition is composed of semen plantaginis-semen raphani decoction concentration extract, semen plantaginis polysaccharides and raphanin in a ratio of (2 to 4): (3 to 7): (5 to 9). The composition has a great curative effect on cancer chemotherapy associated diarrhea and can act a synergistic effect on cancer chemotherapy simultaneously.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition which is composed of the decoction concentrated extract of Semen psyllium radish, polysaccharide of Semen psyllium and radishin, the preparation of the natural medicine composition The method and its use in the preparation of a medicament for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A61P1/12A61P35/00A61K31/715A61K31/26
Inventor 石强
Owner 石强