Gelatin-CaCO3 mineral capsule shell and preparation method thereof

A technology of minerals and capsule shells, which is applied in capsule delivery, food science, non-effective ingredients of polymer compounds, etc., can solve the problems of undiscovered mineral capsule shells, shorten the disintegration time limit, have good elasticity, and reduce the use of gelatin volume effect

Inactive Publication Date: 2013-09-25
TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] By searching, no gelatin-CaCO related to the application of the present invention has been found 3 Published Patent Documents for Mineral Capsule Shells

Method used

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  • Gelatin-CaCO3 mineral capsule shell and preparation method thereof
  • Gelatin-CaCO3 mineral capsule shell and preparation method thereof
  • Gelatin-CaCO3 mineral capsule shell and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A gelatin-CaCO 3 Mineral capsule shells, whose raw materials are gelatin, CaCO 3 , plasticizer, water, consumption is respectively:

[0043] formula Dosage gelatin 27.5g CaCO 3 65.0g

[0044] Plasticizer: Glycerin 6.8g distilled water 100.0g

[0045] The preparation method of above-mentioned capsule shell, comprises the following steps:

[0046] ⑴Material preparation: Weigh 27.5g of gelatin, CaCO 3 Pour 65.0g into a beaker and mix well, take 6.8g of plasticizer, 100.0g of distilled water, pour the mixed gelatin, CaCO 3 In the beaker of the mixture, let it stand for 3-4 hours to make the gelatin fully absorb water and swell;

[0047] (2) Colloidal sol: Heat the material solution that has fully absorbed water and swelled in a constant temperature magnetic stirring water bath (about 60°C, the speed is 1500rpm), and stir fully until the gelatin is completely dissolved to form a glue solution;

[0048] ⑶ Static degassin...

Embodiment 2

[0054] A gelatin-CaCO 3 Mineral capsule shell, its main raw materials are gelatin, CaCO 3 , plasticizer, water, consumption is respectively:

[0055] formula Dosage gelatin 30.0g CaCO 3 60.0g Plasticizer: Glycerin 7.5g distilled water 100.0g

[0056] The preparation method of above-mentioned capsule shell, comprises the following steps:

[0057] ⑴Material preparation: Weigh 30.0g of gelatin, CaCO 3 Pour 60.0g into a beaker and mix well. Measure 7.5g of plasticizer, 100.0g of distilled water, pour into the mixed gelatin, CaCO 3 In the beaker of the mixture, let it stand for 3-4 hours to make the gelatin fully absorb water and swell;

[0058](2) Colloidal sol: Heat the material solution that has fully absorbed water and swelled in a constant temperature magnetic stirring water bath (about 60°C, the speed is 1500rpm), and stir fully until the gelatin is completely dissolved to form a glue solution;

[0059] ⑶ Static degassing: use th...

Embodiment 3

[0065] A gelatin-CaCO 3 Mineral capsule shell, its main raw materials are gelatin, CaCO 3 , plasticizer, water, consumption is respectively:

[0066] formula Dosage gelatin 28.0g CaCO 3 70.0g Plasticizer: Sorbitol 8.5g distilled water 110.0g

[0067] The preparation method of above-mentioned capsule shell is the same as embodiment 1 or 2.

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Abstract

The invention relates to a gelatin-CaCO3 mineral capsule shell and a preparation method thereof. According to the invention, gelatin-CaCO3=1:1.5-3 (W/W). The capsule shell is prepared from the following materials, by weight: 20-50 parts of gelatin, 20-80 parts of CaCO3, 1-10 parts of a plasticizer, and 50-150 parts of water. The preparation method comprises the steps of 1, material preparation; 2, solation; 3, setting and degassing, 4, sol dipping and shaping; 5, bake-drying, de-molding, and cutting; 6, cap and body sleeving, and sterilization; and 7, inspection. The prepared gelatin-CaCO3 mineral capsule shells have the functions of supplementing calcium, enhancing bones, increasing calcium solubility, and promoting body absorption to Ca<2+>. With the existence of the mineral CaCO3, with the crosslinking of carboxyl groups in gelatin and calcium ions in CaCO3, capsule shell dissolving in gastric acid solution can be accelerated, such that the disintegration time limit of the mineral capsule shell is shortened.

Description

technical field [0001] The invention belongs to the field of medicine, food and health product processing, and relates to a capsule shell, especially a gelatin-CaCO 3 Mineral capsule shells and methods for their preparation. Background technique [0002] Capsule shell is an egg-shaped hollow shell used to hold solid powder particles. It has good bioavailability. It enters the human digestive system together with drugs or health food preparations, and can be dissolved quickly, reliably and safely. It is mainly used for In the fields of medicines and health food, it solves the problem of difficult entrance and poor taste of medicines for users. [0003] By searching, no gelatin-CaCO related to the application of the present invention has been found 3 Published Patent Literature for Mineral Capsule Shells. Contents of the invention [0004] The object of the present invention is to provide a kind of gelatin-CaCO 3 A mineral capsule shell and a preparation method thereof. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/42A61K47/02A23P1/04A23P10/30
Inventor 刘安军郑捷郑国强王跃猛刘晨党超
Owner TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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