Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof

A technology for children's hand, foot and mouth disease and traditional Chinese medicine oral liquid, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, antipyretics, etc. Weakness and other problems, to prevent neurological complications, promote healing, and benefit body temperature

Active Publication Date: 2013-10-09
THE FIFTH HOSPITAL OF SHIJIAZHUANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Children are susceptible to infectious diseases, and their resistance is relatively weak. Children's medications are also special. At present, there is no specific drug for the treatment of children's hand, foot and mouth disease in Western medicine. Most of them are treated with antiviral drugs and antibiotics. However, due to Due to the wide selection of such drugs and the poor targeted treatment, children are prone to drug side effects and drug resistance, thereby reducing the curative effect and delaying the course of the disease

Method used

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  • Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof
  • Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof
  • Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The traditional Chinese medicine oral liquid for the treatment of children's hand, foot and mouth disease takes by weighing the following Chinese medicine raw materials:

[0044] Gypsum 480g, Radix Radix 40g, Cimicifuga 40g, Huoxiang 40g, Dandelion 120g, Coptis chinensis 40g, Rhizoma Imperatae 280g, Danpi 40g, Mung bean 280g, Uncaria 320g.

[0045] The preparation method comprises the following steps:

[0046] (1) Extract the above-mentioned traditional Chinese medicine raw materials twice, add 10 times the amount of water for the first time, decoct for 1.5 hours, add 6 times the amount of water for the second time, decoct for 1 hour, and combine the two decoctions;

[0047] (2) When concentrated in a vacuum concentrator to 45°C, the relative density is 1.05-1.15, the temperature is below 60°C during vacuum concentration, and the vacuum degree is 0.08Mpa;

[0048] (3) Centrifuge the concentrated solution obtained in step (2) at a rotation speed of 16000-20000r / min, fil...

Embodiment 2

[0051] The traditional Chinese medicine oral liquid for the treatment of children's hand, foot and mouth disease takes by weighing the following Chinese medicine raw materials:

[0052] Gypsum 680g, Isatis root 200g, Cimicifuga 200g, Huoxiang 200g, Dandelion 320g, Coptis 200g, Imperata 480g, Paeonol 200g, Mung bean 520g, Uncaria 640g.

[0053] The preparation method comprises the following steps:

[0054] (1) Extract the above-mentioned traditional Chinese medicine raw materials twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 7 times the amount of water for the second time, decoct for 2 hours, and combine the two decoctions;

[0055] (2) When concentrated in a vacuum concentrator to 45°C, the relative density is 1.05-1.15, the temperature is below 60°C during vacuum concentration, and the vacuum degree is 0.08Mpa;

[0056] (3) Centrifuge the concentrated solution obtained in step (2) at a rotation speed of 16000-20000r / min, filter, and add ...

Embodiment 3

[0059] The traditional Chinese medicine oral liquid for the treatment of children's hand, foot and mouth disease takes by weighing the following Chinese medicine raw materials:

[0060] Gypsum 500g, Radix Radix 100g, Cimicifuga 100g, Huoxiang 100g, Dandelion 240g, Coptidis 150g, Imperata Rhizoma 300g, Paeonol 100g, Mung Bean 400g, Uncaria 640g.

[0061] The preparation method comprises the following steps:

[0062] (1) Extract the above-mentioned traditional Chinese medicine raw materials twice, add 8 times the amount of water for the first time, decoct for 1.5 hours, add 6 times the amount of water for the second time, decoct for 1.5 hours, and combine the two decoctions;

[0063] (2) When concentrated in a vacuum concentrator to 45°C, the relative density is 1.05-1.15, the temperature is below 60°C during vacuum concentration, and the vacuum degree is 0.08Mpa;

[0064] (3) Centrifuge the concentrated solution obtained in step (2) at a rotation speed of 16000-20000r / min, fil...

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Abstract

The invention discloses a Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and a preparation method thereof. The Chinese medicine oral liquid comprises the following Chinese medicine raw materials in parts by weight: 12-18 parts of gypsum, 1-5 parts of isatis root, 1-5 parts of rhizoma cimicifugae, 1-5 parts of agastache rugosus, 3-8 parts of dandelion, 1-5 parts of coptis, 7-12 parts of lalang grass rhizome, 1-5 parts of cortex moutan, 7-13 parts of mung bean and 8-14 parts of uncaria. The Chinese medicine oral liquid disclosed by the invention can be used for treating fever and herpes, has the effects of promoting the healing of oral ulcer, preventing neurological complications and the like and has the advantages of very good curative effect on regression of rash, no toxic or side effect, remarkable curative effect on ordinary type hand-foot-mouth diseases of children, benefit of the recovery of body temperature, the drying and the incrustation of herpes and the like and capability of rapidly abating fever and obviously reducing the probability that the sick children are turned into severe cases.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine oral liquid for hand, foot and mouth disease. Background technique [0002] Hand foot and mouth disease (HFMD) is mainly caused by infections including enterovirus type 71 and coxsackie virus type 16, and is a childhood infection mainly manifested by fever and rashes on hands, feet, and mouth. It is common in children under 5 years old and can cause herpes on the hands, feet, and mouth. A small number of children may have serious complications such as myocarditis, pulmonary edema, and aseptic meningitis. Individual severe cases often lead to death if the disease develops rapidly. Traditional Chinese medicine believes that hand, foot and mouth disease belongs to the categories of "wind temperature", "dampness temperature" and "seasonal epidemic" in traditional Chinese medicine. Children's spleen is often insufficient, and the lungs are delicate and easily damaged. When the e...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P31/14A61P29/00A61P17/00A61P31/22A61K33/06
Inventor 王文举郑浩杰张照琪刘洪德谭曦然郑艳华薛庆霄戴二黑
Owner THE FIFTH HOSPITAL OF SHIJIAZHUANG
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