Double-wavelength differential near-infrared non-invasive glucose meter

Abstract

The invention discloses a double-wavelength differential near-infrared non-invasive glucose meter. The double-wavelength differential near-infrared non-invasive glucose meter comprises a laser device I (11), a plane mirror I (12), a protective layer (13), a sample (14), a function generator (15), a laser device II (16), an optical neutral density light filter (17), a parabolic mirror I (18), a plane mirror II (19), a phase-locked amplifier (110), a broadband optical near-infrared detector (111), a double-channel optical filter (112) and a parabolic mirror II (113), wherein the optical neutral density light filter can be used for adjusting the power of the laser device II (16), so that the output power ratio of the laser device I (11) to the laser device II (16) is adjusted; and the phase difference is controlled by the function generator (15) and the phase-locked amplifier (110). The double-wavelength differential near-infrared non-invasive glucose meter not only has non-invasive detecting capacity, but also has high measuring precision, especially within a hypoglycemic range by combining the amplitude and the phase characteristics of the near-infrared light and utilizing the crest and trough variation difference of absorption spectrum. Meanwhile, the protective layer is provided for preventing the laser devices from accidently injuring skin tissues.

Description

technical field [0001] The invention relates to a measuring instrument for medically detecting the blood sugar level of diabetic patients, in particular to a dual-wavelength differential near-infrared non-invasive blood glucose meter. Background technique [0002] my country has become the country with the largest number of diabetic patients in the world. The total number of diabetic patients is nearly 100 million, and the number of pre-diabetics is about 150 million. In order to control the development of the disease, diabetic patients need to continuously measure their blood sugar level to achieve the purpose of keeping the blood sugar level in a normal range. At present, the commonly used blood glucose testing instruments clinically are all traumatic, which brings certain misery to the patients. At the same time, we have noticed that people are developing non-invasive blood sugar measurement methods and detection instruments, and have published a number of patents, such ...

AI Technical Summary

Problems solved by technology

At present, the blood glucose testers commonly used in clinical practice are traumatic and bring certain pain to the patients.

At the same time, we have noticed that people are developing non-invasive blood sugar measurement methods and detection instruments, and have published a number of patents, such as "Non-invasive Near-infrared Electronic Blood Glucose Meter" (CN102198004A) using infrared light sources (600-2500nm) to transmit fingers, according to For the absorption spectrum of blood sugar, the blood sugar value is obtained after weighted average of the signals of each sensor in the infrared sensor array by using the mixed expert algorithm of the neural network. , water, fat and protein and other components; "Non-invasive Blood Glucose Monitor" (CN201295231Y) obtains the patient's blood sugar value by measuring the patient's capacitance through two electrodes in contact with the patient's skin; "Non-invasive self-test blood sugar Instrument" (CN1271562A) uses an infrared light emitting tube as an infrared light source (wavelength: 1000-2900nm), and uses a transmission method to measure blood sugar levels. It divides the light path into two paths and enters the same part of the human body through different filters for calibration. Measure the patient's blood sugar level

[0003] The above-mentioned technologies, without exception, measure the amplitude to obtain the corresponding blood sugar value, but are limited by the influence of other tissues (skin, fat, etc.), so that the accuracy is not high. In order to improve the accuracy, reduce the influence of other tissues

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