Comprehensive analysis method of multi-dimensional biology opto-acoustic image spectra

A photoacoustic image and comprehensive analysis technology, applied in the field of biomedicine and image processing, can solve the problem of low diagnostic accuracy of biological tissue lesions

Inactive Publication Date: 2013-11-20
NANJING UNIV
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Problems solved by technology

[0004] Purpose of the invention: The technical problem to be solved by the present invention is to provide a comprehensive analysis method for multi-dimensional photoacoustic image spectrum in view of the low accuracy of preliminary diagnosis of biological tissue lesions

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  • Comprehensive analysis method of multi-dimensional biology opto-acoustic image spectra

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Embodiment Construction

[0021] The present invention establishes a three-dimensional photoacoustic image spectrum database of multiple types of lesions in biological tissues, and comprehensively analyzes the tissues to be diagnosed, thereby obtaining preliminary diagnosis results and improving the accuracy and efficiency of preliminary diagnosis.

[0022] Such as figure 1 As shown, the present invention discloses a method for comprehensive analysis of multi-dimensional photoacoustic image spectrum, comprising the following steps:

[0023] Step 1, selecting tissue samples of various lesion types of a certain type of biological tissue to establish a lesion sample bank;

[0024] Step 2, irradiating a sample with a laser of a certain wavelength to produce a photoacoustic effect, using an ultrasonic sensor to receive a two-dimensional photoacoustic signal, and obtaining a two-dimensional photoacoustic image of the sample;

[0025] Step 3, performing two-dimensional Fourier transform on the image to obtai...

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Abstract

The invention discloses a comprehensive analysis method of multi-dimensional biology opto-acoustic image spectra. The method comprises steps as follows: establishing a disease sample library of certain biological tissue; illuminating a certain sample with laser having a certain wavelength to produce an optoacoustic effect, and collecting a two-dimension opto-acoustic image of the sample; performing two-dimension Fourier transform on the image, obtaining two-dimension opto-acoustic spectrograms, and extracting characteristic spectra of the two-dimension opto-acoustic spectrograms; continuously changing the wavelength of the illuminated laser, and combining a plurality of groups of two-dimension opto-acoustic spectrograms and characteristic spectra into three-dimension opto-acoustic spectrograms and three-dimension characteristic spectra according to different wavelengths; establishing a three-dimension opto-acoustic spectrogram library of all samples of the biological tissue; and acquiring three-dimension opto-acoustic spectrograms of to-be-diagnosed tissue, comparing and matching spectrogram data in the library, and obtaining a primary diagnosis result. According to the method, with the adoption of the optoacoustic effect of the tissue and through analysis of the three-dimension opto-acoustic spectrograms of the to-be-diagnosed tissue, disease conditions are judged in two aspects of a spatial domain and a frequency domain, so that the accuracy of the primary diagnosis is effectively improved.

Description

technical field [0001] The invention relates to the fields of biomedicine and image processing, in particular to a comprehensive analysis method for multi-dimensional photoacoustic image spectrum. Background technique [0002] In the process of medical diagnosis, the initial diagnosis of patients is a very important link, which is the basis for further diagnosis. Therefore, accurate preliminary diagnosis results are conducive to improving the efficiency of follow-up diagnosis and play an important role in the whole diagnosis process. Photoacoustic imaging method is a new type of biological tissue imaging method, which uses the principle of photoacoustic effect of biological tissue, combines the advantages of pure optical tissue imaging and tissue pure acoustic imaging, and traditional X-ray imaging, ultrasound imaging, magnetic resonance imaging Compared with imaging and other methods, it has the advantages of no harm to the human body, high imaging resolution, and high con...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
Inventor 袁杰曹萌张星封婷邵真天朱毅李文超储哲琪顾鹏温馨沈庆宏都思丹
Owner NANJING UNIV
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