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Traditional Chinese medicine composition, preparation method and application thereof

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, pharmaceutical formula, antitumor drug, etc.

Inactive Publication Date: 2013-11-20
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition, preparation method and application thereof

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Experimental program
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Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of concentrated extract of Burnet eucalyptus decoction

[0037] According to the compatibility ratio of 1-4:1, take Burnet and white wood, soak in distilled water, heat and decoct, filter, add distilled water to the medicinal dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and super Membrane filtration, drying under reduced pressure, that is.

[0038] (2) Preparation of total saponins from Burnet burnet

[0039] The dried Burnet medicinal material is crushed, soaked in 70% ethanol overnight, heated and refluxed 3 times, and the extracts are combined to recover the ethanol extract, the ethanol extract is dissolved in water, extracted 3 times with an equal volume of n-butanol, the solvent is recovered under reduced pressure, and vacuum dried. have to.

[0040] (3) Preparation of Chloroform Extract of Akiras sinensis

[0041] Take the coarse powder of ...

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Abstract

The invention relates to a traditional Chinese medicine composition, a preparation method and an application thereof. The traditional Chinese medicine composition is composed of garden burnet and aquilaria sinensis water-decocted concentrated extractive, garden burnet total saponins, chloroform extractive of aquilaria sinensis and hexane extractive of aquilaria sinensis at the ratio of (2-3):(4-6):(2-8):(4-8). The composition in the invention has an excellent curative effect on cancer chemotherapy-induced diarrhea and has a synergism effect on cancer chemotherapy at the same time.

Description

technical field [0001] The present invention relates to a kind of traditional Chinese medicine composition, more specifically relate to a kind of traditional Chinese medicine composition that is composed of the concentrated extract of Burnet burnet, the total saponins of Burnet burnet, the chloroform extract of burnet chinensis and the hexane extract of burnet burnet. The preparation method of the composition and the application of the traditional Chinese medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P35/00A61P1/12
Inventor 石强
Owner 石强