Method for extracting anti-cerebral-ischemia material from roses and application of anti-cerebral ischemia material

Abstract

The invention relates to the method for extracting an anti-cerebral-ischemia material from roses and the application of the anti-cerebral-ischemia material. The problem of extraction of the anti-cerebral-ischemia material from the roses can be effectively solved and the application of rose extractive in preparation of anti-cerebral-ischemia medicine is achieved. The method comprises the following steps that the roses are smashed into medicine powder, and reflux extraction is conducted on the medicine powder through petroleum ether for one hour so that degreasing is completed; residue of the degreased rose medicine powder is filtered out, the petroleum ether is volatilized until the rose medicine powder is dry, and therefore rose powder is obtained; the rose powder is soaked with ethyl alcohol, reflux retraction is conducted for two times, extractive liquid is filtered, decompression is conduced so that the ethyl alcohol can be recycled until the smell of the ethyl alcohol does not exist, concentration is conducted, and distilled water is added to concentration liquid so that the concentration liquid can be dispersed into sample liquid; AB-8 type macroporous resin on the sample liquid is eluted through distilled water, and water liquid is removed; elution is conducted through ethyl alcohol, decompression is conducted so that ethyl alcohol can be recycled, concentration is conducted on the sample liquid until dry powder is obtained, and rose general flavone is obtained. The rose general flavone can be effectively used for preparation of the anti-cerebral-ischemia medicine, and the application of the rose extractive in the preparation of the anti-cerebral-ischemia medicine is achieved. According to the method for extracting the anti-cerebral-ischemia material from roses and the application of the anti-cerebral-ischemia material, raw materials are abundant, the anti-cerebral-ischemia material is easy to prepare, the extractive has the anti-cerebral-ischemia function, and the anti-cerebral-ischemia material is innovation of medicine.

Description

technical field [0001] The invention relates to medicine, in particular to a method for extracting anti-cerebral ischemia substances from rose flowers and its application. Background technique [0002] Ischemic cerebrovascular disease belongs to the scope of "ischemic stroke" in traditional Chinese medicine. It is a focal brain dysfunction caused by insufficient or interrupted local cerebral blood supply, oxygen supply, and common transient ischemic attack, cerebral embolism, cerebral Thrombosis is a common and frequently-occurring disease that seriously threatens human life and health, and is a major disease that leads to death and disability. Ischemia-reperfusion injury (IRI) refers to a pathological phenomenon in which tissue damage is aggravated after a certain period of ischemia and restoration of blood supply. At present, the intervention and treatment of ischemic brain injury by drugs has become an important research topic concerned by the society and the medical com...

AI Technical Summary

Problems solved by technology

But up to now, no report of roses on cerebral ischemia has been found, and the specific active ingredients against cerebral ischemia are still unclear. The main active ingredients in rose alcohol extract are total flavonoids, and how to extract total flavonoids from roses, As yet no public reports

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