Phenytoin sodium dropping pill and preparation method thereof

A technology of sodium phenytoin and sodium dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc. It can solve problems such as inability to quickly exert drug effects, poor curative effect on arrhythmia, large volume and difficulty in swallowing, etc., to achieve The preparation process is simple and easy, the drug compliance is high, and the production cost is low
CN103479591AInactive Publication Date: 2014-01-01天津市聚星康华医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
天津市聚星康华医药科技有限公司
Publication Date
2014-01-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the technical field of medicines, and relates to a phenytoin sodium dropping pill and a preparation method thereof. The phenytoin sodium dropping pill is applicable to treatment of generalized tonic-clonic seizures, complex partial seizures (psychomotor seizures and temporal lobe epilepsy) simple partial seizures (focal seizures) and status epilepticus, can also be used for treating trigeminal neuralgia, epidermolysis bullosa dystrophica recessive, paroxysmal choreoathetosis, paroxysmal control disorders (including behavioral disorders caused by hyperexcitability such as rage, anxiety, insomnia and the like), myotonia, cardiac conduction disorder during overdose of a tricyclic antidepressant and the like, and is also applicable to ventricular and supraventricular arrhythmias caused by digitalis toxication, with a poor therapeutic effect on cardiac arrhythmias caused by other various causes. Compared with currently marketed tablet products, the phenytoin sodium dropping pill has the characteristics of simple and feasible preparation process, rapid absorption and high bioavailability.
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Description

technical field

[0001] The invention belongs to the field of pharmaceutical preparations, and relates to a phenytoin sodium dropping pill and a preparation method thereof. Background technique

[0002] Phenytoin Sodium (PHT-Na), also known as dalentine, is a sodium salt of diphenylhydantoin and is the drug of choice for anti-epileptic grand mal. Anti-mild hypertension. Because phenytoin has a wide range of biological activities and pharmacological therapeutic effects, it is often used in the treatment of other diseases in clinical practice. Many previous side effects are now being tried for the treatment of related diseases, and good results have been achieved, including promoting Wound healing, treatment of migraine, vertigo, hiccups, cardiovascular and cerebrovascular diseases, burns, auditory hallucinations in schizophrenia, anal itching, chlorpromazine-induced depression, scleroderma, etc.

[0003] Animal experiments have shown that phenytoin has a selective antagonist...

Claims

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