Method for preparing nano hydroxyapatite

Abstract

The invention provides a method for preparing rodlike nano hydroxyapatite. The method comprises the steps of weighing (CaNO3)2.4H2O and (NH4)2HPO4 powder, respectively dissolving the powder into water, dropwise adding the (NH4)2HPO4 solution into the (CaNO3)2.4H2O solution under the ultrasonic stirring condition, adding a dispersing agent, adjusting the pH value, aging, centrifuging, and washing the mixture with water to obtain the nano hydroxyapatite. The hydroxyapatite prepared by adopting the method can be well dispersed into a substrate without being specially treated, so that the defect that the agglomeration of the existing hydroxyapatite can be prevented by adding surface dispersing agent can be overcome. The method is simple, the high temperature and high pressure can be avoided, and the industrialized production can be favored.

Description

technical field [0001] The invention relates to a preparation method, more specifically, to a method for preparing nano-hydroxyapatite. Background technique [0002] At present, the production of nano-hydroxyapatite in the prior art is to first produce hydroxyapatite by precipitation method, sol-gel method or hydrothermal method, and then pulverize it to obtain nano-hydroxyapatite. However, after the precipitation method product is dried, it is easy to agglomerate, and the particle size is different, and the uniformity is poor, and it is often necessary to introduce a surface dispersant; the hydrothermal method requires extremely high reaction conditions (high temperature, high pressure), and the production equipment requires extremely high requirements. The cost is high, the safety is poor, and the output of the synthesized product is small, which is not conducive to industrial production; the sol-gel method is prone to agglomeration after calcination. Moreover, the produ...

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Problems solved by technology

However, after the precipitation method product is dried, it is easy to agglomerate, and the particle size is different, and the uniformity is poor, and it is often necessary to introduce a surface dispersant; the hydrothermal method requires extremely high reaction conditions (high temperature, high pressure), and the production equipment requires extremely high requirements. High cost, poor safety, low output of synthesized products, which is not conducive to industrial production; sol-gel method is prone to agglomeration after calcination

Moreover, the production of nano-hydroxyapatite needs to be prepared in two steps, which consumes a lot of energy

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