Application of ganoderma lucidum extract in preparation of health-care foods or cosmetics with anti-radiation and anti-aging effects

A technology of Ganoderma lucidum extract and health food, applied in the field of Ganoderma lucidum, can solve unpublished problems, etc., and achieve the effects of low preparation cost, full utilization of resources, and high extraction efficiency

Active Publication Date: 2014-02-12
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there is no published research on the application of Ganoderma lucidum extr

Method used

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  • Application of ganoderma lucidum extract in preparation of health-care foods or cosmetics with anti-radiation and anti-aging effects
  • Application of ganoderma lucidum extract in preparation of health-care foods or cosmetics with anti-radiation and anti-aging effects
  • Application of ganoderma lucidum extract in preparation of health-care foods or cosmetics with anti-radiation and anti-aging effects

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The preferred preparation method of ganoderma lucidum extract provided in this embodiment comprises the following steps:

[0045] A pre-treatment: wash the raw ganoderma lucidum with water, crush it, sieve it to 30-60 mesh, and weigh 1 kg;

[0046] B extraction: use 8-10 kilograms of methanol to ultrasonically extract at room temperature for 2 times, each time for 20-40 minutes, filter through a 500-800 mesh filter cloth, combine the filtrate, recover methanol under vacuum and decompression, and obtain B extract of raw material weight;

[0047] C extraction: extract in equal proportions with water and ethyl acetate, filter to obtain ethyl acetate extract, recover ethyl acetate under reduced pressure, and obtain C extract with a weight of 10-15 grams of raw materials;

[0048] D loading separation: C extract is accompanied by 20-30 grams of silica gel, then put on a silica gel column, moisten the column with petroleum ether, elute with the ratio of petroleum ether: ethyl...

Embodiment 2

[0051] The preferred preparation method of ganoderma lucidum extract provided in this embodiment comprises the following steps:

[0052] A pre-treatment: wash the raw ganoderma lucidum with water, crush it, sieve it to 30-60 mesh, and weigh 10 kg;

[0053] B extraction: use 80-100 kilograms of methanol to ultrasonically extract at room temperature twice, each time for 20-40 minutes, filter through a 500-800 mesh filter cloth, combine the filtrates, recover methanol under vacuum and decompression, and obtain the B extract of the raw material weight;

[0054] C extraction: extract water and ethyl acetate in equal proportions, filter to obtain ethyl acetate extract, recover ethyl acetate under reduced pressure, and obtain C extract with a weight of 100-150 grams of raw materials;

[0055] D Loading separation: C extract is accompanied by 200-300 grams of silica gel, then put on a silica gel column, moisten the column with petroleum ether, and elute with a volume ratio of petroleu...

Embodiment 3

[0058] The preferred preparation method of ganoderma lucidum extract provided in this embodiment comprises the following steps:

[0059] A pre-treatment: wash the raw ganoderma lucidum with water, crush it, sieve it to 30-60 mesh, and weigh 100 kg;

[0060] B extraction: use 800-1000 kilograms of methanol to ultrasonically extract at room temperature twice, each time for 20-40 minutes, filter with a 500-800 mesh filter cloth, combine the filtrate, recover methanol under vacuum and decompression, and obtain B extract of raw material weight;

[0061] C extraction: extract water and ethyl acetate in an equal volume ratio, filter to obtain ethyl acetate extract, recover ethyl acetate under reduced pressure, and obtain C extract with a weight of 1000-1500 grams of raw materials;

[0062] D sample separation: C extract with 2000-3000 grams of silica gel, then put on a silica gel column, moisten the column with petroleum ether, and elute with the ratio of petroleum ether: ethyl aceta...

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Abstract

The invention discloses application of ganoderma lucidum extract in preparation of health-care foods or cosmetics with anti-radiation and anti-aging effects. The ganoderma lucidum extract has the effect of anti-UVA (ultraviolet A) radiation, can remarkably reduce cell injury caused by UV (ultraviolet) radiation, has a remarkable inhibition effect on macrophage inflammatory factor expression, can play anti-inflammation and anti-aging effects. The invention also explains the anti-UV radiation and anti-aging effects of ganoderma lucidum extract on the aspects of cell and molecular level. Furthermore, the invention also discloses an optional method for preparing the ganoderma lucidum extract with anti-radiation and anti-aging effects.

Description

technical field [0001] The invention belongs to the technical field of ganoderma lucidum, and specifically relates to the application of ganoderma lucidum extract in preparing health food or cosmetics with anti-radiation and anti-aging effects. technical background [0002] In recent years, active ingredients derived from plants have been increasingly used in compositions for medicinal, therapeutic, and cosmetic purposes. At present, plant Ganoderma lucidum extract is used in various medicine and health care. [0003] Aging is a physiological phenomenon, and its physiological manifestation is the decline of the functions of various organs, leading to the occurrence of various aging diseases. And the most intuitive evidence is the aging of the skin. At the molecular level, it is manifested as cellular senescence, which is a gradual event that accompanies the aging of the body. Aging not only leads to the degradation of the body's physiological functions, but also the gradu...

Claims

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Application Information

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IPC IPC(8): A23L1/28A23L1/29A61K8/99A61Q19/08A61Q17/04A23L31/00
CPCA23L31/00A23L33/105A23V2002/00A61K8/99A61Q17/04A61Q19/08A23V2200/30
Inventor 赵宏伟王一飞吴志韻袁晓邹士玉马忠华
Owner INFINITUS (CHINA) CO LTD
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