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Hainanmycin sodium solution and preparation method thereof
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A technology of Hainanmycin sodium and solution, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., to achieve the effects of improving breeding efficiency, significant curative effect and low cost
Inactive Publication Date: 2015-02-18
SHANDONG DEZHOU SHENNIU ANIMAL HEALTH PROD CO LTD
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[0004] In order to solve the problem that the hainamycin sodium premix is difficult to mix in the process of preventing and treating diseases by mixing materials, the present invention provides a kind of Hainanmycin sodium solution, which is group-administered, convenient to produce, has definite curative effect, and adapts to the habit of large-scale drinking water for poultry
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Embodiment 1
[0029] Example 1, A hainanmycin sodium solution containing the following components:
[0032] (1) Take 95% ethanol, add Hainanmycin Sodium, Anluoxue and stir to dissolve completely;
[0033] (2) Then add Tween-80, stir to completely dissolve the mixture;
[0034] (3) 1g of thiourea is completely dissolved in 20g of propylene glycol, added to the mixed solution prepared in step (2), and stirred to completely dissolve;
[0035] (4) Add the remaining propylene glycol, stir to dissolve completely, and filter to obtain.
[0036] Use 0.22-0.45μm organic filter membrane for filtration.
[0040] The solution was prepared using the following method:
[0041] (1) Take 95% ethanol, add Hainanmycin Sodium, Anluoxue and stir to dissolve completely;
[0042] (2) Then add Tween-80, stir to completely dissolve the mixture;
[0043] (3) 2g of sodium thiosulfate is completely dissolved in 25g of propylene glycol, added to the mixture prepared in step (2), and stirred to completely dissolve;
[0044] (4) Add the remaining propylene glycol, stir to dissolve completely, and filter to obtain.
[0045] Use 0.22-0.45μm organic filter membrane for filtration.
[0046] Sterilize after filtration, fill with nitrogen, and pack.
Embodiment 3
[0047] Example 3. A kind of Hainanmycin sodium solution
[0049] The solution was prepared using the following method:
[0050] (1) Take 95% ethanol, add Hainanmycin Sodium, Anluoxue and stir to dissolve completely;
[0051] (2) Then add Tween-80, stir to completely dissolve the mixture;
[0052] (3) 2g of sodium bisulfite is completely dissolved in 30g of propylene glycol, added to the mixed solution prepared in step (2), and stirred to completely dissolve;
[0053] (4) Add the remaining propylene glycol, stir to dissolve completely, and filter to obtain.
[0054] Use 0.22-0.45μm organic filter membrane for filtration.
[0055] Sterilize after filtration, fill with nitrogen, and pack.
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Abstract
The present invention relates to the technical field of hainanmycin sodium, in particular to a solution of hainanmycin sodium, hainanmycin sodium, Anluoxue, 95% ethanol, antioxidant, Tween-80 and propylene glycol in a mass ratio of 0.5 to 10: 0.5~2.5: 20~50: 0.5~5: 5~20: 20~70. The solution of the present invention is a uniform and stable system, can be dissolved in water in any proportion, and can be applied to the prevention and treatment of various coccidiosis in broilers. It is quick-acting, long-acting, high-efficiency, low-toxic and less irritating to local tissues. The bioavailability of the product, and its ability to adapt to the habit of large-scale drinking water for poultry, is very popular among farmers; the preparation method of the invention is simple and controllable, with low cost, significant curative effect, convenient clinical use, and is beneficial to the prevention and treatment of poultry coccidiosis. Prevention and control can reduce the labor cost of farmers and improve breeding efficiency.
Description
technical field [0001] The invention relates to the technical field of hainanmycin sodium, in particular to a hainanmycin sodium solution, and also to a preparation method of the hainanmycin sodium solution. Background technique [0002] Hainanmycin Sodium is a monovalent glycoside polyether ionophore antibiotic. It is a polyether antibiotic extracted from the culture medium of a Streptomyces clusus var. orientalis isolated from the soil of Hainan Island in my country. An original anti-coccidiosisdrug with intellectual property rights. It has a broad antibacterial spectrum against Gram-positive bacteria such as bacillus and cocci. It is effective against anaerobic and certain plant pathogens, rice sheath blight and rape sclerotinia. Fungi such as fungi also have antibacterial effects, and have significant effects on preventing coccidiosis infection in chickens and improving feed conversion rates in ruminants. Coccidiosis is a parasitic disease that damages the intestinal t...
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Application Information
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