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Preparation method and use of spine date seed extract having effects of protecting liver and bladder and improving immunity

A technology of jujube seed extract, liver protection and gallbladder protection, applied in medical preparations containing active ingredients, application, animal feed, etc., can solve the problems of destroying the benign situation of poultry export and damaging the economic benefits of farmers

Inactive Publication Date: 2014-03-12
TIANJIN REBATE SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It damages the economic benefits of farmers and destroys the benign situation of poultry export

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The preparation of embodiment 1 Suanzaoren extract

[0012] Dry 150g Ziziphus jujube kernels in a microwave oven at 60°C for 2 hours, then crush them through a 10-mesh sieve, add 5 times the amount of petroleum ether to the screened matter, soak and degrease for 5 hours, evaporate the petroleum ether after the degreasing is complete, and then add 5 times the amount to the residue of Zizinus jujube kernels Soak in 75% ethanol for 2 hours, extract continuously for 5 times, remove the alcohol from the obtained extract, add 3 times the amount of water and stir evenly, then add 5 times the amount of ethyl acetate for continuous extraction 4 times, concentrate and dry, and obtain 8.5g jujube seed extract Paste, its extraction rate is 5.67%.

Embodiment 2

[0013] The preparation of embodiment 2 Suanzaoren extract

[0014] Dry 100g Ziziphus jujube kernels in a microwave oven at 60°C for 1.5 hours, then crush them through a 10-mesh sieve, add 3 times the amount of petroleum ether to the sieved matter, soak and degrease for 2 hours, evaporate the petroleum ether after the degreasing is complete, and then add 3 times Soak in 80% ethanol for 0.5h, extract 2 times continuously, remove alcohol from the obtained extract, add 2 times the amount of water and stir evenly, then add 1.5 times the amount of ethyl acetate, extract continuously 3 times, concentrate and dry, and obtain 5.8g Ziziphus jujube Ren extract, its extraction rate is 5.8%.

Embodiment 3

[0015] The preparation of embodiment 3 Suanzaoren extract

[0016] Dry 150g Ziziphus jujube kernels in a microwave oven at 60°C for 3 hours, then crush them through a 10-mesh sieve, add 9 times the amount of petroleum ether to the screened matter, soak and degrease for 8 hours, evaporate the petroleum ether after the degreasing is complete, and then add 9 times the amount to the residue of Zizinus jujube kernels Soak in 95% ethanol for 3 hours, extract 8 times continuously, remove the alcohol from the obtained extract, add 5 times the amount of water and stir evenly, then add 6 times the amount of ethyl acetate to extract 5 times continuously, concentrate and dry, and obtain 9.6g jujube seed extract Cream, its extraction rate is 6.4%.

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Abstract

The invention relates to spine date seed extract having effects of protecting liver and bladder and improving immunity and its preparation method and use. The preparation method of the spine date seed extract comprises the following steps of drying spine date seeds by microwave, carrying out crushing and sieving, carrying out degreasing, carrying out immersion extraction by ethanol, carrying out extraction by ethyl acetate, and carrying out pressure reduction distillation drying. The spine date seed extract can be processed by the conventional methods to form tablets, granules, a freeze-dried powder injection and an oral solution. The spine date seed extract can be used for preparation of a traditional Chinese medicine composition having effects of protecting liver and bladder and improving immunity, and can replace antibiotics for production practices of prevention and treatment on livestock and poultry diseases thereby preventing drug residues, guaranteeing animal source food safety and eliminating the animal product export trade barrier.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, in particular to a preparation method and application of jujube seed extract, which has the functions of protecting liver and gallbladder and enhancing body immunity. Background technique [0002] With the continuous development of my country's poultry industry and the increase of feed additives, poultry liver and gallbladder and other diseases have also increased, especially broiler yellow and white scours, which are often accompanied by a decline in the body's immunity. Reduce the survival rate of poultry. It has damaged the economic benefits of farmers and destroyed the benign situation of poultry export. The jujube seed extract, which has the functions of protecting the liver and gallbladder and enhancing the body's immunity, has the effects of calming down, protecting the liver, protecting the gallbladder and enhancing immunity. After oral administration, it can promote the digestion of yo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61P1/16A61P37/04A23K1/16
Inventor 安同伟陈庆忠李迎梅黄树霞
Owner TIANJIN REBATE SCI & TECH DEV
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