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Compound medicine for treating autoimmunity thrombocytopenic purpura

An autoimmune, platelet technology, used in drug combinations, blood diseases, pharmaceutical formulations, etc., can solve the problems of poor compliance with side effects, poor efficacy, and unsatisfactory efficacy in thrombocytopenic purpura. quick results

Inactive Publication Date: 2014-05-14
徐艳艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment often has poor compliance due to side effects caused by repeated application of prednisone and other immunosuppressants, and the longer the course of the disease, the worse the curative effect
Chinese patent 200910075890.1 discloses a drug for treating allergic purpura. Radix Paeoniae Rubra, Raw Glycyrrhiza and other components, the drug has heat-clearing and cooling blood, blood stasis, hemostasis and anti-allergic effects, can treat allergic purpura, but the curative effect on autoimmune thrombocytopenic purpura is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: The preparation method of the compound medicine of autoimmune thrombocytopenic purpura comprises the following steps,

[0036] Step 1) Take Rehmannia glutinosa 9, Shengdi 15, Chrysanthemum notoginseng 19, Scrophulariaceae 15, Scutellaria baicalensis 12, Forsythia 8, Small thistle 13, Gardenia 10 according to the weight ratio, and weigh each medicinal ingredient and each component, Dried at 80°C to 95°C, crushed into the finest powder, and passed through a 50-mesh sieve; according to the weight ratio, take 12 mountain bean root, 13 Digupi 13, 45 Imperata rhizome, 8 velvet grass, 13 buffalo horn, and 9 Alisma , Rubia 12, Angelica 10, Cortex Moutan 10, dried at 60°C to 70°C, crushed into the finest powder, and passed through an 80-mesh sieve;

[0037] Step 2) Decoct the sieved fine powder of each active ingredient and each component obtained in step 1) and add 12 times the mass of water until the decoction is filtered and the filtrate is concentrated to an oi...

Embodiment 2

[0040] Embodiment 2: The preparation method of the compound medicine of autoimmune thrombocytopenic purpura comprises the following steps,

[0041]Step 1) Take rehmannia glutinosa 6, rehmannia glutinosa 20, chrysanthemum notoginseng 10, scrophulariae scrophulariae 20, scutellaria baicalensis 9, forsythia 10, small thistle 12, and gardenia 15 according to the weight ratio, weigh each medicinal component and each component, and weigh them in the Dried at 80°C to 95°C, crushed into the finest powder, and sieved through a 50-mesh sieve; according to the proportions by weight, take 9 root of mountain bean root, 15 bark of Digupi 15, 30 root of Imperata piloscens, 10 velvet grass, 10 buffalo horn, and 12 Alisma. , yam 15, madder 15, angelica 6, moutan bark 15, dried at 60°C to 70°C, crushed into the finest powder, and passed through a 80-mesh sieve;

[0042] Step 2) decoct the sieved fine powder of each active ingredient and each component obtained in step 1) and add 14 times the ma...

Embodiment 3

[0045] Embodiment 3: The preparation method of the compound medicine of autoimmune thrombocytopenic purpura comprises the following steps,

[0046] Step 1) Take Rehmannia glutinosa 12, Shengdi 10, Chrysanthemum notoginseng 25, Scrophulariae scrophulariae 10, Scutellaria baicalensis 9, Forsythia 10, Small thistle 12, Gardenia 15 according to the weight ratio, weigh each medicinal ingredient and each component, Dried at 80°C to 95°C, crushed into the finest powder, and passed through a 50-mesh sieve; according to the weight ratio, take 9 to 15 pea root, 10 to 15 stem bark, 30 Imperata rhizome, 10 velvet grass, 10 buffalo horn, Alisma 12, Yam 15, Rubia 15, Angelica 6, Moutan bark 15, dried at 60°C-70°C, crushed into the finest powder, passed through 80-mesh sieve;

[0047] Step 2) decoct the sieved fine powder of each active ingredient and each component obtained in step 1) and add 10 times the mass of water until the decoction is filtered and the filtrate is concentrated to an o...

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Abstract

The invention relates to a compound medicine for treating autoimmunity thrombocytopenic purpura. The compound medicine comprises effective ingredients and adjuvant ingredients, wherein the effective ingredients are prepared from the following components in parts by weight: 6-12 parts of processed Rehmannia glutinosa, 10-20 parts of Rehmannia glutinosa, 10-25 parts of Gynura japonica, 10-20 parts of Scrophularia ningpoensis, 9-15 parts of Scutellaria baicalensis, 5-10 parts of Forsythia suspensa, 12-15 parts of Cirsium setosum and 9-15 parts of Gardenia jasminoides fruit. The adjuvant ingredients are prepared from the following components in parts by weight: 9-15 parts of Sophora tonkinensis root,10-15 parts of Cortex Lycii (Lycium chinense and / or Lycium barbarum), 30-60 parts of Imperata cylindrica root, 5-10 parts of Monochasma sheareri, 10-20 parts of Bubalus bubalis horn, 6-12 parts of Alisma orientalis, 10-15 parts of Rubia cordifolia, 6-12 parts of Angelica sinensis, and 6-15 parts of Paeonia suffruticosa root bark. The components of the effective ingredient and the adjuvant ingredient are reasonably compounded to take synergistic effect. Chinese medicinal materials with effects of eliminating pathogenic heat from the blood and promoting blood circulation are used. The compound medicine can be used for treating autoimmunity thrombocytopenic purpura and has the advantages of quick action, stable therapeutic effect, and so on.

Description

technical field [0001] The invention relates to a compound medicine for treating autoimmune thrombocytopenic purpura. Background technique [0002] Autoimmune thrombocytopenic purpura is a clinical syndrome of increased platelet destruction due to immune mechanism, also known as idiopathic thrombocytopenic purpura, which is a relatively common bleeding disease, characterized by peripheral thrombocytopenia and shortened platelet life span. Bone marrow megakaryocytes are normal or increased, and the platelet turnover rate is accelerated. According to clinical manifestations, age of onset, duration of thrombocytopenia and treatment effect, it is divided into acute type and chronic type. The acute type is more common in children and is often self-limiting, while the chronic type is more common in young women. The vast majority of patients with chronic autoimmune thrombocytopenic purpura have no prodromal symptoms or etiology. The incidence rate of women is higher than that of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P7/04A61K35/32
Inventor 徐艳艳
Owner 徐艳艳
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