Method for simultaneously determining content of 1,2-propylene glycol, menthol, diethylene glycol, glycerin and triethylene glycol in electronic cigarette juice

A technology for e-cigarette liquid and propylene glycol, which is applied to measurement devices, instruments, scientific instruments, etc., can solve the problems such as the content of triethylene glycol and menthol in e-cigarette liquid that have not yet been measured, and achieve universality and ease of use. Good effect of promotion, repeatability and recovery rate

Active Publication Date: 2014-05-21
CHINA NAT TOBACCO QUALITY SUPERVISION & TEST CENT
View PDF3 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there has been no report on the determination of triethylene glycol and menthol in e-cigarette liquid

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for simultaneously determining content of 1,2-propylene glycol, menthol, diethylene glycol, glycerin and triethylene glycol in electronic cigarette juice
  • Method for simultaneously determining content of 1,2-propylene glycol, menthol, diethylene glycol, glycerin and triethylene glycol in electronic cigarette juice
  • Method for simultaneously determining content of 1,2-propylene glycol, menthol, diethylene glycol, glycerin and triethylene glycol in electronic cigarette juice

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] 1. Instruments, reagents and instrument working conditions

[0033] 1) Instrument

[0034] SCION 456-GC gas chromatograph with hydrogen flame ionization detector (GC-FID, Bruker Daltonic, USA); AE163 electronic balance (sensitivity: 0.0001 g, Mettler, Switzerland); ultrasonic generator (KQ-700DB CNC ultrasonic cleaner).

[0035] 2) Reagents

[0036] 1,3-butanediol (internal standard, CAS: 107-88-0), 1,2-propanediol (CAS: 57-55-6), menthol (CAS: 89-78-1) diethylene glycol ( CAS: 111-46-6), glycerol (CAS: 56-81-5), triethylene glycol (CAS: 112-27-6), n-heptadecane (629-78-7), 1, 4-Butanediol (110-63-4), all standard; Methanol (chromatographically pure, TEDIA, USA); Electronic cigarette samples were purchased online.

[0037] 3) Gas chromatography conditions. Chromatographic column: 30 m × 0.25 mmid × 0.25 μmdf polyethylene glycol elastic capillary column (DB-WAX column or other equivalent column); inlet temperature: 250 ° C; carrier gas: nitrogen (purity ≥ 99.999%) , ...

Embodiment 2

[0057] According to the method described in Example 1, an electronic cigarette liquid B was selected, and the contents of 1,2-propanediol, menthol and glycerol were measured to be 71.39%, 1.15% and 14.86%, respectively, and diethylene glycol and triethylene glycol None were detected.

Embodiment 3

[0059] According to the method described in Example 1, an electronic cigarette liquid C was selected, and the contents of 1,2-propanediol, glycerol and triethylene glycol were measured to be 61.31%, 25.98% and 0.37%, respectively, and menthol and diethylene glycol Alcohol was not detected.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
recovery rateaaaaaaaaaa
Login to view more

Abstract

The invention provides a method for simultaneously determining the content of 1,2-propylene glycol, menthol, diethylene glycol, glycerin and triethylene glycol in electronic cigarette juice. The method is characterized by comprising the following steps: preparing a sample solution to be tested by adopting an ultrasonic extraction method and a mixed standard working solution with the 7-grade concentration gradient, analyzing by using a gas chromatograph provided with a hydrogen flame ionization detector, and quantifying by using an internal standard method. Results show that when the concentration of the 1,2- propylene glycol, the menthol, the diethylene glycol, the glycerin and the triethylene glycol is in the range of 0.001-1.0mg / mL, the linear relationship among the 1,2-propylene glycol, the menthol, the diethylene glycol, the glycerin and the triethylene glycol is good (R<2> is greater than 0.999), the limit of detection (LOD) is 0.0028-0.0057%, the average recovery rate of thee labeling levels is in the range of 94.8%-104.4%, and the relative standard deviation (DSR) is less than 4.96%, and according to the method, the sensitivity is high in sensitivity, and repeatability and recovery rate are good.

Description

technical field [0001] The invention relates to the technical field of physical and chemical inspection of electronic cigarette products, in particular to a gas chromatography method for simultaneously measuring the contents of 1,2-propanediol, menthol, diethylene glycol, glycerol and triethylene glycol in electronic cigarette liquid. Background technique [0002] In recent years, the topic of smoking and health has been widely concerned by people, and smoking is harmful to health has been generally recognized by people. In 2005, China signed the "Framework Convention on Tobacco Control", which provided a legal basis for tobacco control. In 2012, the Chinese government issued the "China Tobacco Control Plan (2012-2015)", proposing to create a smoke-free environment and implement a comprehensive ban on smoking in public places. Electronic cigarettes (e-cigarettes), also known as electronic nicotine delivery systems (ENDS), are a new form of nicotine intake that looks similar ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02
Inventor 韩书磊陈欢刘彤吴帅宾侯宏卫胡清源
Owner CHINA NAT TOBACCO QUALITY SUPERVISION & TEST CENT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap