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Pharmaceutical composition for treating hyperlipemia

A composition and a technology for hyperlipidemia, applied in the field of medicine, can solve the problems of unclear curative effect, excessive prescription, rare and rare, and achieve the effects of good curative effect, small side effects and low manufacturing cost.

Inactive Publication Date: 2014-06-04
QINGDAO TUMOR HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But among them, some of the prescriptions are too large and the curative effect is not clear, and some of them are expensive because of the use of precious medicinal materials in the prescriptions, and the drugs that can be successfully marketed are even rarer.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Accurately weigh 240g of Sanleng, 120g of Leulu, 60g of Gynostemma, 480g of Eucommia, 360g of Polygonum multiflorum, 360g of Radix Vermilione, 480g of Turmeric, 240g of Burdock, 180g of Centella asiatica, 160g of Licorice, dry, crush, pass through a 200-mesh sieve, and Bacteria, filled with size 0 capsules.

Embodiment 2

[0035] Accurately weigh 180g of Sanleng, 60g of Leulu, 40g of Gynostemma, 400g of Eucommia, 300g of Polygonum multiflorum, 240g of Vermilion, 400g of Turmeric, 300g of Burdock, 120g of Centella asiatica, 120g of Licorice, dry, crush, pass through a 200-mesh sieve, and Bacteria, filled with size 0 capsules.

Embodiment 3

[0036] Embodiment 3, animal acute toxicity test of the present invention

[0037] Medicine: the prescription of embodiment 3 of the present invention.

[0038] Experimental animals: 12 normal-grade NIH mice, weighing 18g±2g, half male and half male.

[0039] Method and Results:

[0040] 1) Drug preparation: take the prescription of Example 1, and prepare 200g / L suspension with physiological saline containing 2% gum arabic:

[0041] 2) The experiment adopts intragastric administration. One-time administration, volume 2ml / 100g body weight, close observation for 8 hours and record, continue observation for 7 days;

[0042] 3) In 7 days, the mice did not die, their behaviors were active, their food intake was normal, their coat color was bright without looseness and dirt, they had no convulsions and salivation, no abnormal secretions from eyes, mouth, nose, ears and perianal area, and no broken tails and toes. Choose 5 to put to death, see with the naked eye: important viscera...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating hyperlipemia, which is characterized by being prepared from the following traditional Chinese medicines in parts by weight: 12-24 parts of rhizoma sparganii, 6-12 parts of uniflower swisscentaury root, 4-8 parts of fiveleaf gynostemma herb, 40-60 parts of cortex eucommiae, 30-60 parts of polygonum multiflorum, 20-40 parts of herba potentillae discoloris, 40-60 parts of rhizoma curcumae longae, 20-60 parts of fructus arctii, 12-24 parts of herba centellae and 12-18 parts of liquoric root. The traditional Chinese medicine composition provided by the invention has the advantages of obvious curative effect, little side effect, high effective rate and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating hyperlipidemia. Background technique [0002] Hyperlipidemia is a common and frequently-occurring disease in middle-aged and elderly people. With the improvement of people's living standards and changes in living habits, the incidence of this disease has increased significantly, and the age of onset has also advanced. Atherosclerosis caused by hyperlipidemia is the main cause of coronary heart disease, hypertension and cerebrovascular disease. Therefore, the treatment of hyperlipidemia is very important, which has attracted great attention from all mankind. The ultimate goal of treating hyperlipidemia is to inhibit the further development of arteriosclerosis, thereby preventing death caused by diseases such as cardiovascular and cerebrovascular diseases. [0003] At present, Western medicine is mainly used for the treatment of hyperlip...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P3/06A61P9/10A61P7/02
Inventor 刘雨
Owner QINGDAO TUMOR HOSPITAL
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